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Neuropeptide S Receptor (NPSR)

ASRT2; GPR154; GPRA; NPSR1; PGR14; VRR1; G Protein-Coupled Receptor For Asthma Susceptibility; G Protein-Coupled Receptor 154; G-protein coupled receptor PGR14

The NPSR) is a member of the G-protein coupled receptor superfamily of integral membrane proteins which binds neuropeptide S (NPS). It was formally an orphan receptor, GPR154, until the discovery of neuropeptide S as the endogenous ligand.In the CNS, activation of the NPSR by NPS promotes arousal and anxiolytic-like effects.
In addition, mututations in NPSR have been linked to a susceptibility to asthma. Hence NPSR has also been called GPRA (G protein-coupled receptor for asthma susceptibility). Activation of NPSR in the airway epithelium has a number of effects including upregulation of matrix metalloproteinases which are involved in the pathogenesis of asthma.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Neuropeptide S Receptor (NPSR) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Neuropeptide S Receptor (NPSR) Bioactivity
Antibodies MT896Hu21 Monoclonal Antibody to Neuropeptide S Receptor (NPSR) WB; IHC; ICC; IP.
PT896Hu01 Polyclonal Antibody to Neuropeptide S Receptor (NPSR) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) Flow Cytometry;ICC/IF
Assay Kits KET896Hu ELISA Kit for Neuropeptide S Receptor (NPSR) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Neuropeptide S Receptor (NPSR) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Neuropeptide S Receptor (NPSR) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Neuropeptide S Receptor (NPSR) Bioactivity
Antibodies NONE Monoclonal Antibody to Neuropeptide S Receptor (NPSR) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Neuropeptide S Receptor (NPSR) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Neuropeptide S Receptor (NPSR) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Neuropeptide S Receptor (NPSR) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Neuropeptide S Receptor (NPSR) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Neuropeptide S Receptor (NPSR) Bioactivity
Antibodies NONE Monoclonal Antibody to Neuropeptide S Receptor (NPSR) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Neuropeptide S Receptor (NPSR) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Neuropeptide S Receptor (NPSR) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Neuropeptide S Receptor (NPSR) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Neuropeptide S Receptor (NPSR) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Neuropeptide S Receptor (NPSR) Bioactivity
Antibodies NONE Monoclonal Antibody to Neuropeptide S Receptor (NPSR) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Neuropeptide S Receptor (NPSR) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Neuropeptide S Receptor (NPSR) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Neuropeptide S Receptor (NPSR) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Neuropeptide S Receptor (NPSR) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Neuropeptide S Receptor (NPSR) Bioactivity
Antibodies NONE Monoclonal Antibody to Neuropeptide S Receptor (NPSR) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Neuropeptide S Receptor (NPSR) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Neuropeptide S Receptor (NPSR) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Neuropeptide S Receptor (NPSR) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Neuropeptide S Receptor (NPSR) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Neuropeptide S Receptor (NPSR) Bioactivity
Antibodies NONE Monoclonal Antibody to Neuropeptide S Receptor (NPSR) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Neuropeptide S Receptor (NPSR) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Neuropeptide S Receptor (NPSR) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Neuropeptide S Receptor (NPSR) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Neuropeptide S Receptor (NPSR) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Neuropeptide S Receptor (NPSR) Bioactivity
Antibodies NONE Monoclonal Antibody to Neuropeptide S Receptor (NPSR) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Neuropeptide S Receptor (NPSR) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Neuropeptide S Receptor (NPSR) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Neuropeptide S Receptor (NPSR) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Neuropeptide S Receptor (NPSR) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Neuropeptide S Receptor (NPSR) Bioactivity
Antibodies NONE Monoclonal Antibody to Neuropeptide S Receptor (NPSR) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Neuropeptide S Receptor (NPSR) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Neuropeptide S Receptor (NPSR) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Neuropeptide S Receptor (NPSR) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Neuropeptide S Receptor (NPSR) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Neuropeptide S Receptor (NPSR) Bioactivity
Antibodies NONE Monoclonal Antibody to Neuropeptide S Receptor (NPSR) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Neuropeptide S Receptor (NPSR) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Neuropeptide S Receptor (NPSR) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Neuropeptide S Receptor (NPSR) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Neuropeptide S Receptor (NPSR) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Neuropeptide S Receptor (NPSR) Bioactivity
Antibodies NONE Monoclonal Antibody to Neuropeptide S Receptor (NPSR) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Neuropeptide S Receptor (NPSR) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Neuropeptide S Receptor (NPSR) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Neuropeptide S Receptor (NPSR) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Neuropeptide S Receptor (NPSR) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Neuropeptide S Receptor (NPSR) Bioactivity
Antibodies NONE Monoclonal Antibody to Neuropeptide S Receptor (NPSR) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Neuropeptide S Receptor (NPSR) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Neuropeptide S Receptor (NPSR) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Neuropeptide S Receptor (NPSR) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Neuropeptide S Receptor (NPSR) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Neuropeptide S Receptor (NPSR) Bioactivity
Antibodies NONE Monoclonal Antibody to Neuropeptide S Receptor (NPSR) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Neuropeptide S Receptor (NPSR) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Neuropeptide S Receptor (NPSR) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Neuropeptide S Receptor (NPSR) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Neuropeptide S Receptor (NPSR) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Neuropeptide S Receptor (NPSR) Bioactivity
Antibodies NONE Monoclonal Antibody to Neuropeptide S Receptor (NPSR) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Neuropeptide S Receptor (NPSR) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Neuropeptide S Receptor (NPSR) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Neuropeptide S Receptor (NPSR) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Neuropeptide S Receptor (NPSR) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Neuropeptide S Receptor (NPSR) Bioactivity
Antibodies NONE Monoclonal Antibody to Neuropeptide S Receptor (NPSR) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Neuropeptide S Receptor (NPSR) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Neuropeptide S Receptor (NPSR) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Neuropeptide S Receptor (NPSR) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Neuropeptide S Receptor (NPSR) CLIA assay for Antigen Detection

Reference

"Characterization of a common susceptibility locus for asthma-related traits."
Science 304:300-304(2004) [PubMed] [Europe PMC] [Abstract]

"Characterization of GPRA, a novel G protein-coupled receptor related to asthma."
Am. J. Respir. Cell Mol. Biol. 33:262-270(2005) [PubMed] [Europe PMC] [Abstract]

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Neuropeptide S: a neuropeptide promoting arousal and anxiolytic-like effects."
Neuron 43:487-497(2004) [PubMed] [Europe PMC] [Abstract]

"Haplotypes of G protein-coupled receptor 154 are associated with childhood allergy and asthma."
Am. J. Respir. Crit. Care Med. 171:1089-1095(2005) [PubMed] [Europe PMC] [Abstract]

"G-protein-coupled receptor polymorphisms are associated with asthma in a large German population."
Am. J. Respir. Crit. Care Med. 171:1358-1362(2005) [PubMed] [Europe PMC] [Abstract]

"Structure-function relationships in the neuropeptide S receptor: molecular consequences of the asthma-associated mutation N107I."
J. Biol. Chem. 281:24704-24712(2006) [PubMed] [Europe PMC] [Abstract]