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Protease Activated Receptor 4 (PAR4)

F2RL3; PAR-4; Coagulation Factor II Thrombin Receptor-Like 3; Coagulation factor II receptor-like 3

Protease-activated receptors 1 (PAR1), 2 (PAR2), and 3 (PAR3) are members of a unique G protein-coupled receptor family. They are characterized by a tethered peptide ligand at the extracellular amino terminus that is generated by minor proteolysis.By fluorescence in situ hybridization, Xu et al. (1998) mapped the PAR4 gene to 19p12.
Coagulation factor II (thrombin) receptor-like 3 (F2RL3) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL3 is also a member of the protease-activated receptor family. F2RL3 is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. F2RL3 is activated by thrombin and trypsin.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins T829Hu01 Recombinant Protease Activated Receptor 4 (PAR4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Protease Activated Receptor 4 (PAR4) Bioactivity
Antibodies MT829Hu22 Monoclonal Antibody to Protease Activated Receptor 4 (PAR4) WB; IHC; ICC; IP.
PT829Hu01 Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) Flow Cytometry;ICC/IF
Assay Kits KET829Hu ELISA Kit for Protease Activated Receptor 4 (PAR4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Protease Activated Receptor 4 (PAR4) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Protease Activated Receptor 4 (PAR4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Protease Activated Receptor 4 (PAR4) Bioactivity
Antibodies NONE Monoclonal Antibody to Protease Activated Receptor 4 (PAR4) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Protease Activated Receptor 4 (PAR4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Protease Activated Receptor 4 (PAR4) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins T829Ra01 Recombinant Protease Activated Receptor 4 (PAR4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Protease Activated Receptor 4 (PAR4) Bioactivity
Antibodies MT829Ra21 Monoclonal Antibody to Protease Activated Receptor 4 (PAR4) WB; IHC; ICC; IP.
PT829Ra01 Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) Flow Cytometry;ICC/IF
Assay Kits KET829Ra ELISA Kit for Protease Activated Receptor 4 (PAR4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Protease Activated Receptor 4 (PAR4) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Protease Activated Receptor 4 (PAR4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Protease Activated Receptor 4 (PAR4) Bioactivity
Antibodies NONE Monoclonal Antibody to Protease Activated Receptor 4 (PAR4) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Protease Activated Receptor 4 (PAR4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Protease Activated Receptor 4 (PAR4) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Protease Activated Receptor 4 (PAR4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Protease Activated Receptor 4 (PAR4) Bioactivity
Antibodies NONE Monoclonal Antibody to Protease Activated Receptor 4 (PAR4) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Protease Activated Receptor 4 (PAR4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Protease Activated Receptor 4 (PAR4) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Protease Activated Receptor 4 (PAR4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Protease Activated Receptor 4 (PAR4) Bioactivity
Antibodies NONE Monoclonal Antibody to Protease Activated Receptor 4 (PAR4) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Protease Activated Receptor 4 (PAR4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Protease Activated Receptor 4 (PAR4) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Protease Activated Receptor 4 (PAR4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Protease Activated Receptor 4 (PAR4) Bioactivity
Antibodies NONE Monoclonal Antibody to Protease Activated Receptor 4 (PAR4) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Protease Activated Receptor 4 (PAR4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Protease Activated Receptor 4 (PAR4) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Protease Activated Receptor 4 (PAR4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Protease Activated Receptor 4 (PAR4) Bioactivity
Antibodies NONE Monoclonal Antibody to Protease Activated Receptor 4 (PAR4) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Protease Activated Receptor 4 (PAR4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Protease Activated Receptor 4 (PAR4) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Protease Activated Receptor 4 (PAR4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Protease Activated Receptor 4 (PAR4) Bioactivity
Antibodies NONE Monoclonal Antibody to Protease Activated Receptor 4 (PAR4) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Protease Activated Receptor 4 (PAR4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Protease Activated Receptor 4 (PAR4) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Protease Activated Receptor 4 (PAR4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Protease Activated Receptor 4 (PAR4) Bioactivity
Antibodies NONE Monoclonal Antibody to Protease Activated Receptor 4 (PAR4) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Protease Activated Receptor 4 (PAR4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Protease Activated Receptor 4 (PAR4) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Protease Activated Receptor 4 (PAR4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Protease Activated Receptor 4 (PAR4) Bioactivity
Antibodies NONE Monoclonal Antibody to Protease Activated Receptor 4 (PAR4) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Protease Activated Receptor 4 (PAR4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Protease Activated Receptor 4 (PAR4) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Protease Activated Receptor 4 (PAR4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Protease Activated Receptor 4 (PAR4) Bioactivity
Antibodies NONE Monoclonal Antibody to Protease Activated Receptor 4 (PAR4) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Protease Activated Receptor 4 (PAR4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Protease Activated Receptor 4 (PAR4) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Protease Activated Receptor 4 (PAR4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Protease Activated Receptor 4 (PAR4) Bioactivity
Antibodies NONE Monoclonal Antibody to Protease Activated Receptor 4 (PAR4) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Protease Activated Receptor 4 (PAR4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Protease Activated Receptor 4 (PAR4) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Protease Activated Receptor 4 (PAR4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Protease Activated Receptor 4 (PAR4) Bioactivity
Antibodies NONE Monoclonal Antibody to Protease Activated Receptor 4 (PAR4) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Protease Activated Receptor 4 (PAR4) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Protease Activated Receptor 4 (PAR4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Protease Activated Receptor 4 (PAR4) CLIA assay for Antigen Detection

Reference

"Gene and locus structure and chromosomal localization of the protease-activated receptor gene family."
J. Biol. Chem. 273:23290-23296(1998) [PubMed] [Europe PMC] [Abstract]

"A dual thrombin receptor system for platelet activation."
Nature 394:690-694(1998) [PubMed] [Europe PMC] [Abstract]

"Cloning and characterization of human protease-activated receptor 4."
Proc. Natl. Acad. Sci. U.S.A. 95:6642-6646(1998) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Protease-activated receptors 1 and 4 mediate activation of human platelets by thrombin."
J. Clin. Invest. 103:879-887(1999) [PubMed] [Europe PMC] [Abstract]