Galectin 12 (GAL12)

LGALS12; GRIP1; Lectin,Galactoside-Binding Soluble 12; Galectin-related inhibitor of proliferation

SPN	T823
HGNC	15788
MGI	1929094
PubMed	15131127
RGD	1306914
UniProt	Q96DT0

Galectins constitute a family of proteins that bind to β-galactoside residues and have diverse physiological functions. Report on the identification of a galectin-like molecule, galectin-12, in a human adipose tissue cDNA library. The protein contained two potential carbohydrate-recognition domains with the second carbohydrate-recognition domain being less conserved compared with other galectins.

Galectin-12 mRNA was predominantly expressed in adipose tissue of human and mouse and in differentiated 3T3-L1 adipocytes. Caloric restriction and treatment of obese animals with troglitazone increased galectin-12 mRNA levels and decreased the average size of the cells in adipose tissue.

Organism species: Homo sapiens (Human)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPT823Hu01	Recombinant Galectin 12 (GAL12)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAT823Hu01	Monoclonal Antibody to Galectin 12 (GAL12)	WB; IHC; ICC; IP.
Antibodies	PAT823Hu01	Polyclonal Antibody to Galectin 12 (GAL12)	WB; IHC; ICC; IF.
Assay Kits	CLT823Hu01	CLIA Kit for Galectin 12 (GAL12)	CLIA assay for Antigen Detection
Assay Kits	ELT823Hu01	ELISA Kit for Galectin 12 (GAL12)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPT823Mu01	Recombinant Galectin 12 (GAL12)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAT823Mu01	Monoclonal Antibody to Galectin 12 (GAL12)	WB; IHC; ICC; IP.
Antibodies	PAT823Mu01	Polyclonal Antibody to Galectin 12 (GAL12)	WB; IHC; ICC; IF.
Assay Kits	CLT823Mu01	CLIA Kit for Galectin 12 (GAL12)	CLIA assay for Antigen Detection
Assay Kits	ELT823Mu01	ELISA Kit for Galectin 12 (GAL12)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPT823Ra01	Recombinant Galectin 12 (GAL12)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAT823Ra01	Monoclonal Antibody to Galectin 12 (GAL12)	WB; IHC; ICC; IP.
Antibodies	PAT823Ra01	Polyclonal Antibody to Galectin 12 (GAL12)	WB; IHC; ICC; IF.
Assay Kits	CLT823Ra01	CLIA Kit for Galectin 12 (GAL12)	CLIA assay for Antigen Detection
Assay Kits	ELT823Ra01	ELISA Kit for Galectin 12 (GAL12)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPT823Ca01	Recombinant Galectin 12 (GAL12)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAT823Ca01	Monoclonal Antibody to Galectin 12 (GAL12)	WB; IHC; ICC; IP.
Antibodies	PAT823Ca01	Polyclonal Antibody to Galectin 12 (GAL12)	WB; IHC; ICC; IF.
Assay Kits	CLT823Ca01	CLIA Kit for Galectin 12 (GAL12)	CLIA assay for Antigen Detection
Assay Kits	ELT823Ca01	ELISA Kit for Galectin 12 (GAL12)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPT823Po01	Recombinant Galectin 12 (GAL12)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAT823Po01	Monoclonal Antibody to Galectin 12 (GAL12)	WB; IHC; ICC; IP.
Antibodies	PAT823Po01	Polyclonal Antibody to Galectin 12 (GAL12)	WB; IHC; ICC; IF.
Assay Kits	CLT823Po01	CLIA Kit for Galectin 12 (GAL12)	CLIA assay for Antigen Detection
Assay Kits	ELT823Po01	ELISA Kit for Galectin 12 (GAL12)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPT823Bo01	Recombinant Galectin 12 (GAL12)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAT823Bo01	Monoclonal Antibody to Galectin 12 (GAL12)	WB; IHC; ICC; IP.
Antibodies	PAT823Bo01	Polyclonal Antibody to Galectin 12 (GAL12)	WB; IHC; ICC; IF.
Assay Kits	CLT823Bo01	CLIA Kit for Galectin 12 (GAL12)	CLIA assay for Antigen Detection
Assay Kits	ELT823Bo01	ELISA Kit for Galectin 12 (GAL12)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPT823Rb01	Recombinant Galectin 12 (GAL12)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAT823Rb01	Monoclonal Antibody to Galectin 12 (GAL12)	WB; IHC; ICC; IP.
Antibodies	PAT823Rb01	Polyclonal Antibody to Galectin 12 (GAL12)	WB; IHC; ICC; IF.
Assay Kits	CLT823Rb01	CLIA Kit for Galectin 12 (GAL12)	CLIA assay for Antigen Detection
Assay Kits	ELT823Rb01	ELISA Kit for Galectin 12 (GAL12)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPT823Mo01	Recombinant Galectin 12 (GAL12)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAT823Mo01	Monoclonal Antibody to Galectin 12 (GAL12)	WB; IHC; ICC; IP.
Antibodies	PAT823Mo01	Polyclonal Antibody to Galectin 12 (GAL12)	WB; IHC; ICC; IF.
Assay Kits	CLT823Mo01	CLIA Kit for Galectin 12 (GAL12)	CLIA assay for Antigen Detection
Assay Kits	ELT823Mo01	ELISA Kit for Galectin 12 (GAL12)	Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"Galectin-12, an adipose-expressed galectin-like molecule possessing apoptosis-inducing activity."
J. Biol. Chem. 276:34089-34097(2001) [PubMed] [Europe PMC] [Abstract]

"Cell cycle regulation by galectin-12, a new member of the galectin superfamily."
J. Biol. Chem. 276:20252-20260(2001) [PubMed] [Europe PMC] [Abstract]

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"Human chromosome 11 DNA sequence and analysis including novel gene identification."
Nature 440:497-500(2006) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]