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Histidyl tRNA Synthetase (HARS)
Histidyl tRNA Synthetase (HARS)
HRS; Jo1; Jo-1; HisRS; Histidine tRNA Ligase 1,Cytoplasmic
Histidyl-tRNA synthetase (HARS) also known as histidine-tRNA ligase, is an enzyme which in humans is encoded by the HARS gene.Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is a cytoplasmic enzyme which belongs to the class II family of aminoacyl tRNA synthetases.
The enzyme is responsible for the synthesis of histidyl-transfer RNA, which is essential for the incorporation of histidine into proteins. The gene is located in a head-to-head orientation with HARSL on chromosome five, where the homologous genes share a bidirectional promoter.TISSUE SPECIFICITY: Brain, heart, liver and kidney.
Organism species: Homo sapiens (Human)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
T784Hu01
Recombinant Histidyl tRNA Synthetase (HARS) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Histidyl tRNA Synthetase (HARS) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Histidyl tRNA Synthetase (HARS) WB; IHC; ICC; IP.
PT784Hu01
Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Histidyl tRNA Synthetase (HARS) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Histidyl tRNA Synthetase (HARS) CLIA assay for Antigen Detection
Organism species: Mus musculus (Mouse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Histidyl tRNA Synthetase (HARS) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Histidyl tRNA Synthetase (HARS) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Histidyl tRNA Synthetase (HARS) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Histidyl tRNA Synthetase (HARS) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Histidyl tRNA Synthetase (HARS) CLIA assay for Antigen Detection
Organism species: Rattus norvegicus (Rat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Histidyl tRNA Synthetase (HARS) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Histidyl tRNA Synthetase (HARS) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Histidyl tRNA Synthetase (HARS) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Histidyl tRNA Synthetase (HARS) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Histidyl tRNA Synthetase (HARS) CLIA assay for Antigen Detection
Organism species: Canis familiaris; Canine (Dog)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Histidyl tRNA Synthetase (HARS) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Histidyl tRNA Synthetase (HARS) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Histidyl tRNA Synthetase (HARS) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Histidyl tRNA Synthetase (HARS) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Histidyl tRNA Synthetase (HARS) CLIA assay for Antigen Detection
Organism species: Sus scrofa; Porcine (Pig)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Histidyl tRNA Synthetase (HARS) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Histidyl tRNA Synthetase (HARS) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Histidyl tRNA Synthetase (HARS) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Histidyl tRNA Synthetase (HARS) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Histidyl tRNA Synthetase (HARS) CLIA assay for Antigen Detection
Organism species: Bos taurus; Bovine (Cattle)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Histidyl tRNA Synthetase (HARS) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Histidyl tRNA Synthetase (HARS) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Histidyl tRNA Synthetase (HARS) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Histidyl tRNA Synthetase (HARS) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Histidyl tRNA Synthetase (HARS) CLIA assay for Antigen Detection
Organism species: Rhesus monkey (Simian)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Histidyl tRNA Synthetase (HARS) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Histidyl tRNA Synthetase (HARS) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Histidyl tRNA Synthetase (HARS) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Histidyl tRNA Synthetase (HARS) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Histidyl tRNA Synthetase (HARS) CLIA assay for Antigen Detection
Organism species: Chicken (Gallus)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Histidyl tRNA Synthetase (HARS) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Histidyl tRNA Synthetase (HARS) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Histidyl tRNA Synthetase (HARS) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Histidyl tRNA Synthetase (HARS) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Histidyl tRNA Synthetase (HARS) CLIA assay for Antigen Detection
Organism species: Ovis aries; Ovine (Sheep)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Histidyl tRNA Synthetase (HARS) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Histidyl tRNA Synthetase (HARS) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Histidyl tRNA Synthetase (HARS) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Histidyl tRNA Synthetase (HARS) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Histidyl tRNA Synthetase (HARS) CLIA assay for Antigen Detection
Organism species: Oryctolagus cuniculus (Rabbit)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Histidyl tRNA Synthetase (HARS) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Histidyl tRNA Synthetase (HARS) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Histidyl tRNA Synthetase (HARS) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Histidyl tRNA Synthetase (HARS) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Histidyl tRNA Synthetase (HARS) CLIA assay for Antigen Detection
Organism species: Cavia (Guinea pig )
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Histidyl tRNA Synthetase (HARS) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Histidyl tRNA Synthetase (HARS) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Histidyl tRNA Synthetase (HARS) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Histidyl tRNA Synthetase (HARS) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Histidyl tRNA Synthetase (HARS) CLIA assay for Antigen Detection
Organism species: Equus caballus; Equine (Horse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Histidyl tRNA Synthetase (HARS) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Histidyl tRNA Synthetase (HARS) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Histidyl tRNA Synthetase (HARS) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Histidyl tRNA Synthetase (HARS) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Histidyl tRNA Synthetase (HARS) CLIA assay for Antigen Detection
Organism species: Capra hircus; Caprine (Goat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Histidyl tRNA Synthetase (HARS) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Histidyl tRNA Synthetase (HARS) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Histidyl tRNA Synthetase (HARS) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Histidyl tRNA Synthetase (HARS) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Histidyl tRNA Synthetase (HARS) CLIA assay for Antigen Detection
Organism species: Pan-species (General)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Histidyl tRNA Synthetase (HARS) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Histidyl tRNA Synthetase (HARS) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Histidyl tRNA Synthetase (HARS) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Histidyl tRNA Synthetase (HARS) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Histidyl tRNA Synthetase (HARS) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Histidyl tRNA Synthetase (HARS) CLIA assay for Antigen Detection
Reference
"Human histidyl-tRNA synthetase: recognition of amino acid signature regions in class 2a aminoacyl-tRNA synthetases." Nucleic Acids Res. 20:1075-1081(1992) [PubMed ] [Europe PMC ] [Abstract ]
"Isolation, structure and expression of mammalian genes for histidyl-tRNA synthetase." Nucleic Acids Res. 15:3349-3367(1987) [PubMed ] [Europe PMC ] [Abstract ]
"Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed ] [Europe PMC ] [Abstract ]
"The DNA sequence and comparative analysis of human chromosome 5." Nature 431:268-274(2004) [PubMed ] [Europe PMC ] [Abstract ]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." Genome Res. 14:2121-2127(2004) [PubMed ] [Europe PMC ] [Abstract ]
"Transcriptional analyses of the gene region that encodes human histidyl-tRNA synthetase: identification of a novel bidirectional regulatory element." Gene 131:201-208(1993) [PubMed ] [Europe PMC ] [Abstract ]
"A novel gene oriented in a head-to-head configuration with the human histidyl-tRNA synthetase (HRS) gene encodes an mRNA that predicts a polypeptide homologous to HRS." Biochem. Biophys. Res. Commun. 210:556-566(1995) [PubMed ] [Europe PMC ] [Abstract ]
"Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach." Anal. Chem. 81:4493-4501(2009) [PubMed ] [Europe PMC ] [Abstract ]
"Initial characterization of the human central proteome." BMC Syst. Biol. 5:17-17(2011) [PubMed ] [Europe PMC ] [Abstract ]
"A loss-of-function variant in the human histidyl-tRNA synthetase (HARS) gene is neurotoxic in vivo." Hum. Mutat. 34:191-199(2013) [PubMed ] [Europe PMC ] [Abstract ]
"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome." J. Proteomics 96:253-262(2014) [PubMed ] [Europe PMC ] [Abstract ]
"Solution structures of the WHEP-TRS domain of human histidyl-tRNA synthetase." Submitted (NOV-2005) to the PDB data bank
"Genetic mapping and exome sequencing identify variants associated with five novel diseases." PLoS ONE 7:E28936-E28936(2012) [PubMed ] [Europe PMC ] [Abstract ]