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Isoleucyl tRNA Synthetase (IARS)

IARS1; ILRS; OJ; IleRS; IRS; Isoleucine tRNA Ligase 1,Cytoplasmic

Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution.
Isoleucine-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family and has been identified as a target of autoantibodies in the autoimmune disease polymyositis/dermatomyositis. Two alternatively spliced variants have been isolated that represent alternate 5' UTRs.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Isoleucyl tRNA Synthetase (IARS) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Isoleucyl tRNA Synthetase (IARS) Bioactivity
Antibodies MT779Hu21 Monoclonal Antibody to Isoleucyl tRNA Synthetase (IARS) WB; IHC; ICC; IP.
PT779Hu01 Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) Flow Cytometry;ICC/IF
Assay Kits KET779Hu ELISA Kit for Isoleucyl tRNA Synthetase (IARS) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Isoleucyl tRNA Synthetase (IARS) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Isoleucyl tRNA Synthetase (IARS) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Isoleucyl tRNA Synthetase (IARS) Bioactivity
Antibodies NONE Monoclonal Antibody to Isoleucyl tRNA Synthetase (IARS) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Isoleucyl tRNA Synthetase (IARS) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Isoleucyl tRNA Synthetase (IARS) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Isoleucyl tRNA Synthetase (IARS) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Isoleucyl tRNA Synthetase (IARS) Bioactivity
Antibodies NONE Monoclonal Antibody to Isoleucyl tRNA Synthetase (IARS) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Isoleucyl tRNA Synthetase (IARS) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Isoleucyl tRNA Synthetase (IARS) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Isoleucyl tRNA Synthetase (IARS) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Isoleucyl tRNA Synthetase (IARS) Bioactivity
Antibodies NONE Monoclonal Antibody to Isoleucyl tRNA Synthetase (IARS) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Isoleucyl tRNA Synthetase (IARS) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Isoleucyl tRNA Synthetase (IARS) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Isoleucyl tRNA Synthetase (IARS) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Isoleucyl tRNA Synthetase (IARS) Bioactivity
Antibodies NONE Monoclonal Antibody to Isoleucyl tRNA Synthetase (IARS) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Isoleucyl tRNA Synthetase (IARS) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Isoleucyl tRNA Synthetase (IARS) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Isoleucyl tRNA Synthetase (IARS) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Isoleucyl tRNA Synthetase (IARS) Bioactivity
Antibodies NONE Monoclonal Antibody to Isoleucyl tRNA Synthetase (IARS) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Isoleucyl tRNA Synthetase (IARS) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Isoleucyl tRNA Synthetase (IARS) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Isoleucyl tRNA Synthetase (IARS) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Isoleucyl tRNA Synthetase (IARS) Bioactivity
Antibodies NONE Monoclonal Antibody to Isoleucyl tRNA Synthetase (IARS) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Isoleucyl tRNA Synthetase (IARS) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Isoleucyl tRNA Synthetase (IARS) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Isoleucyl tRNA Synthetase (IARS) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Isoleucyl tRNA Synthetase (IARS) Bioactivity
Antibodies NONE Monoclonal Antibody to Isoleucyl tRNA Synthetase (IARS) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Isoleucyl tRNA Synthetase (IARS) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Isoleucyl tRNA Synthetase (IARS) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Isoleucyl tRNA Synthetase (IARS) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Isoleucyl tRNA Synthetase (IARS) Bioactivity
Antibodies NONE Monoclonal Antibody to Isoleucyl tRNA Synthetase (IARS) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Isoleucyl tRNA Synthetase (IARS) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Isoleucyl tRNA Synthetase (IARS) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Isoleucyl tRNA Synthetase (IARS) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Isoleucyl tRNA Synthetase (IARS) Bioactivity
Antibodies NONE Monoclonal Antibody to Isoleucyl tRNA Synthetase (IARS) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Isoleucyl tRNA Synthetase (IARS) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Isoleucyl tRNA Synthetase (IARS) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Isoleucyl tRNA Synthetase (IARS) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Isoleucyl tRNA Synthetase (IARS) Bioactivity
Antibodies NONE Monoclonal Antibody to Isoleucyl tRNA Synthetase (IARS) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Isoleucyl tRNA Synthetase (IARS) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Isoleucyl tRNA Synthetase (IARS) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Isoleucyl tRNA Synthetase (IARS) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Isoleucyl tRNA Synthetase (IARS) Bioactivity
Antibodies NONE Monoclonal Antibody to Isoleucyl tRNA Synthetase (IARS) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Isoleucyl tRNA Synthetase (IARS) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Isoleucyl tRNA Synthetase (IARS) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Isoleucyl tRNA Synthetase (IARS) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Isoleucyl tRNA Synthetase (IARS) Bioactivity
Antibodies NONE Monoclonal Antibody to Isoleucyl tRNA Synthetase (IARS) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Isoleucyl tRNA Synthetase (IARS) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Isoleucyl tRNA Synthetase (IARS) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Isoleucyl tRNA Synthetase (IARS) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Isoleucyl tRNA Synthetase (IARS) Bioactivity
Antibodies NONE Monoclonal Antibody to Isoleucyl tRNA Synthetase (IARS) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Isoleucyl tRNA Synthetase (IARS) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Isoleucyl tRNA Synthetase (IARS) CLIA assay for Antigen Detection

Reference

"Human cytoplasmic isoleucyl-tRNA synthetase: selective divergence of the anticodon-binding domain and acquisition of a new structural unit."
Proc. Natl. Acad. Sci. U.S.A. 91:7435-7439(1994) [PubMed] [Europe PMC] [Abstract]

"Human isoleucyl-tRNA synthetase: sequence of the cDNA, alternative mRNA splicing, and the characteristics of an unusually long C-terminal extension."
Gene 155:299-304(1995) [PubMed] [Europe PMC] [Abstract]

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"The full-ORF clone resource of the German cDNA consortium."
BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]

"DNA sequence and analysis of human chromosome 9."
Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]

"A quantitative atlas of mitotic phosphorylation."
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]

"Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]

"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]

"Initial characterization of the human central proteome."
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

"System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]

"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]

"Mutations in the enzyme glutathione peroxidase 4 cause Sedaghatian-type spondylometaphyseal dysplasia."
J. Med. Genet. 51:470-474(2014) [PubMed] [Europe PMC] [Abstract]