Triadin (TRDN)
TDN; TRISK; TRISK51
Triadin, also known as TRDN, associated with the release of Calcium ions from the sarcoplasmic reticulum triggering muscular contraction through calcium-induced calcium release.
Triadin, a protein found in rabbit triadic junctions, is intrinsic to the terminal cisternae and is closely associated with the RYR1. The predicted 729-amino acid human protein shares 95% identity with rabbit triadin. Like the rabbit protein, human triadin contains a small cytoplasmic domain and a single transmembrane domain. Human triadin has a calculated pI of 9.3 and molecular mass of 82 kD. However, on Western blots, its apparent molecular mass is 117 kD.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT751Hu01 | Recombinant Triadin (TRDN) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT751Hu01 | Monoclonal Antibody to Triadin (TRDN) | WB; IHC; ICC; IP. |
| PAT751Hu01 | Polyclonal Antibody to Triadin (TRDN) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT751Hu01 | CLIA Kit for Triadin (TRDN) | CLIA assay for Antigen Detection |
| ELT751Hu01 | ELISA Kit for Triadin (TRDN) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT751Mu01 | Recombinant Triadin (TRDN) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT751Mu01 | Monoclonal Antibody to Triadin (TRDN) | WB; IHC; ICC; IP. |
| PAT751Mu01 | Polyclonal Antibody to Triadin (TRDN) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT751Mu01 | CLIA Kit for Triadin (TRDN) | CLIA assay for Antigen Detection |
| ELT751Mu01 | ELISA Kit for Triadin (TRDN) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT751Ra01 | Recombinant Triadin (TRDN) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT751Ra01 | Monoclonal Antibody to Triadin (TRDN) | WB; IHC; ICC; IP. |
| PAT751Ra01 | Polyclonal Antibody to Triadin (TRDN) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT751Ra01 | CLIA Kit for Triadin (TRDN) | CLIA assay for Antigen Detection |
| ELT751Ra01 | ELISA Kit for Triadin (TRDN) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT751Ca01 | Recombinant Triadin (TRDN) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT751Ca01 | Monoclonal Antibody to Triadin (TRDN) | WB; IHC; ICC; IP. |
| PAT751Ca01 | Polyclonal Antibody to Triadin (TRDN) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT751Ca01 | CLIA Kit for Triadin (TRDN) | CLIA assay for Antigen Detection |
| ELT751Ca01 | ELISA Kit for Triadin (TRDN) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT751Po01 | Recombinant Triadin (TRDN) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT751Po01 | Monoclonal Antibody to Triadin (TRDN) | WB; IHC; ICC; IP. |
| PAT751Po01 | Polyclonal Antibody to Triadin (TRDN) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT751Po01 | CLIA Kit for Triadin (TRDN) | CLIA assay for Antigen Detection |
| ELT751Po01 | ELISA Kit for Triadin (TRDN) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT751Bo01 | Recombinant Triadin (TRDN) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT751Bo01 | Monoclonal Antibody to Triadin (TRDN) | WB; IHC; ICC; IP. |
| PAT751Bo01 | Polyclonal Antibody to Triadin (TRDN) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT751Bo01 | CLIA Kit for Triadin (TRDN) | CLIA assay for Antigen Detection |
| ELT751Bo01 | ELISA Kit for Triadin (TRDN) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT751Rb01 | Recombinant Triadin (TRDN) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT751Rb01 | Monoclonal Antibody to Triadin (TRDN) | WB; IHC; ICC; IP. |
| PAT751Rb01 | Polyclonal Antibody to Triadin (TRDN) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT751Rb01 | CLIA Kit for Triadin (TRDN) | CLIA assay for Antigen Detection |
| ELT751Rb01 | ELISA Kit for Triadin (TRDN) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT751Mo01 | Recombinant Triadin (TRDN) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT751Mo01 | Monoclonal Antibody to Triadin (TRDN) | WB; IHC; ICC; IP. |
| PAT751Mo01 | Polyclonal Antibody to Triadin (TRDN) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT751Mo01 | CLIA Kit for Triadin (TRDN) | CLIA assay for Antigen Detection |
| ELT751Mo01 | ELISA Kit for Triadin (TRDN) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Molecular cloning of the cDNA encoding human skeletal muscle triadin and its localisation to chromosome 6q22-6q23."
Eur. J. Biochem. 233:258-265(1995) [PubMed] [Europe PMC] [Abstract]
"The DNA sequence and analysis of human chromosome 6."
Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Calsequestrin mutant D307H exhibits depressed binding to its protein targets and a depressed response to calcium."
Cardiovasc. Res. 64:227-233(2004) [PubMed] [Europe PMC] [Abstract]
"Absence of triadin, a protein of the calcium release complex, is responsible for cardiac arrhythmia with sudden death in human."
Hum. Mol. Genet. 21:2759-2767(2012) [PubMed] [Europe PMC] [Abstract]
"Distinct regions of triadin are required for targeting and retention at the junctional domain of the sarcoplasmic reticulum."
Biochem. J. 458:407-417(2014) [PubMed] [Europe PMC] [Abstract]