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Arachidonate Lipoxygenase 3 (ALOXE3)

ALOX-E3; LOX3; eLOX3; E-LOX; Epidermis-Type Lipoxygenase 3; Hydroperoxy icosatetraenoate dehydratase; Hydroperoxide isomerase ALOXE3

LOX-3is a member of the lipoxygenase family, which are catabolized by arachidonic acid-derived compounds. The encoded enzyme is a hydroperoxide isomerase that synthesizes a unique type of epoxy alcohol (8R-hydroxy-11R,12R-epoxyeicosa-5Z,9E,14Z-trienoic acid) from 12R-hydroperoxyeicosatetraenoic acid (12R-HPETE).
This epoxy alcohol can activate the the nuclear receptor peroxisome proliferator-activated receptor alpha (PPARalpha), which is implicated in epidermal differentiation. Loss of function of the enzyme encoded by this gene results in ichthyosis, implicating the function of this gene in the differentiation of human skin. This gene is part of a cluster of lipoxygenase genes on 17p13.1. Mutations in this gene result in nonbullous congenital ichthyosiform erythroderma (NCIE).

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins T701Hu01 Recombinant Arachidonate Lipoxygenase 3 (ALOXE3) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Arachidonate Lipoxygenase 3 (ALOXE3) Bioactivity
Antibodies MT701Hu21 Monoclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) WB; IHC; ICC; IP.
PT701Hu01 Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) Flow Cytometry;ICC/IF
Assay Kits KET701Hu ELISA Kit for Arachidonate Lipoxygenase 3 (ALOXE3) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Arachidonate Lipoxygenase 3 (ALOXE3) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Arachidonate Lipoxygenase 3 (ALOXE3) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Arachidonate Lipoxygenase 3 (ALOXE3) Bioactivity
Antibodies NONE Monoclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Arachidonate Lipoxygenase 3 (ALOXE3) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Arachidonate Lipoxygenase 3 (ALOXE3) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Arachidonate Lipoxygenase 3 (ALOXE3) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Arachidonate Lipoxygenase 3 (ALOXE3) Bioactivity
Antibodies NONE Monoclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Arachidonate Lipoxygenase 3 (ALOXE3) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Arachidonate Lipoxygenase 3 (ALOXE3) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Arachidonate Lipoxygenase 3 (ALOXE3) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Arachidonate Lipoxygenase 3 (ALOXE3) Bioactivity
Antibodies NONE Monoclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Arachidonate Lipoxygenase 3 (ALOXE3) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Arachidonate Lipoxygenase 3 (ALOXE3) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Arachidonate Lipoxygenase 3 (ALOXE3) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Arachidonate Lipoxygenase 3 (ALOXE3) Bioactivity
Antibodies NONE Monoclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Arachidonate Lipoxygenase 3 (ALOXE3) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Arachidonate Lipoxygenase 3 (ALOXE3) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Arachidonate Lipoxygenase 3 (ALOXE3) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Arachidonate Lipoxygenase 3 (ALOXE3) Bioactivity
Antibodies NONE Monoclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Arachidonate Lipoxygenase 3 (ALOXE3) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Arachidonate Lipoxygenase 3 (ALOXE3) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Arachidonate Lipoxygenase 3 (ALOXE3) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Arachidonate Lipoxygenase 3 (ALOXE3) Bioactivity
Antibodies NONE Monoclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Arachidonate Lipoxygenase 3 (ALOXE3) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Arachidonate Lipoxygenase 3 (ALOXE3) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Arachidonate Lipoxygenase 3 (ALOXE3) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Arachidonate Lipoxygenase 3 (ALOXE3) Bioactivity
Antibodies NONE Monoclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Arachidonate Lipoxygenase 3 (ALOXE3) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Arachidonate Lipoxygenase 3 (ALOXE3) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Arachidonate Lipoxygenase 3 (ALOXE3) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Arachidonate Lipoxygenase 3 (ALOXE3) Bioactivity
Antibodies NONE Monoclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Arachidonate Lipoxygenase 3 (ALOXE3) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Arachidonate Lipoxygenase 3 (ALOXE3) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Arachidonate Lipoxygenase 3 (ALOXE3) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Arachidonate Lipoxygenase 3 (ALOXE3) Bioactivity
Antibodies NONE Monoclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Arachidonate Lipoxygenase 3 (ALOXE3) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Arachidonate Lipoxygenase 3 (ALOXE3) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Arachidonate Lipoxygenase 3 (ALOXE3) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Arachidonate Lipoxygenase 3 (ALOXE3) Bioactivity
Antibodies NONE Monoclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Arachidonate Lipoxygenase 3 (ALOXE3) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Arachidonate Lipoxygenase 3 (ALOXE3) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Arachidonate Lipoxygenase 3 (ALOXE3) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Arachidonate Lipoxygenase 3 (ALOXE3) Bioactivity
Antibodies NONE Monoclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Arachidonate Lipoxygenase 3 (ALOXE3) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Arachidonate Lipoxygenase 3 (ALOXE3) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Arachidonate Lipoxygenase 3 (ALOXE3) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Arachidonate Lipoxygenase 3 (ALOXE3) Bioactivity
Antibodies NONE Monoclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Arachidonate Lipoxygenase 3 (ALOXE3) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Arachidonate Lipoxygenase 3 (ALOXE3) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Arachidonate Lipoxygenase 3 (ALOXE3) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Arachidonate Lipoxygenase 3 (ALOXE3) Bioactivity
Antibodies NONE Monoclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Arachidonate Lipoxygenase 3 (ALOXE3) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Arachidonate Lipoxygenase 3 (ALOXE3) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Arachidonate Lipoxygenase 3 (ALOXE3) CLIA assay for Antigen Detection

Reference

"A gene cluster encoding human epidermis-type lipoxygenases at chromosome 17p13.1: cloning, physical mapping, and expression."
Genomics 73:323-330(2001) [PubMed] [Europe PMC] [Abstract]

"The lipoxygenase gene ALOXE3 implicated in skin differentiation encodes a hydroperoxide isomerase."
Proc. Natl. Acad. Sci. U.S.A. 100:9162-9167(2003) [PubMed] [Europe PMC] [Abstract]

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Human and mouse eLOX3 have distinct substrate specificities: implications for their linkage with lipoxygenases in skin."
Arch. Biochem. Biophys. 455:188-196(2006) [PubMed] [Europe PMC] [Abstract]

"Dioxygenase activity of epidermal lipoxygenase-3 unveiled: typical and atypical features of its catalytic activity with natural and synthetic polyunsaturated fatty acids."
J. Biol. Chem. 285:39866-39875(2010) [PubMed] [Europe PMC] [Abstract]

"On the role of molecular oxygen in lipoxygenase activation: comparison and contrast of epidermal lipoxygenase-3 with soybean lipoxygenase-1."
J. Biol. Chem. 285:39876-39887(2010) [PubMed] [Europe PMC] [Abstract]

"Lipoxygenases mediate the effect of essential fatty acid in skin barrier formation: a proposed role in releasing omega-hydroxyceramide for construction of the corneocyte lipid envelope."
J. Biol. Chem. 286:24046-24056(2011) [PubMed] [Europe PMC] [Abstract]

"Lipoxygenase-3 (ALOXE3) and 12(R)-lipoxygenase (ALOX12B) are mutated in non-bullous congenital ichthyosiform erythroderma (NCIE) linked to chromosome 17p13.1."
Hum. Mol. Genet. 11:107-113(2002) [PubMed] [Europe PMC] [Abstract]

"Mutations associated with a congenital form of ichthyosis (NCIE) inactivate the epidermal lipoxygenases 12R-LOX and eLOX3."
Biochim. Biophys. Acta 1686:238-247(2005) [PubMed] [Europe PMC] [Abstract]

"Mutation spectrum and functional analysis of epidermis-type lipoxygenases in patients with autosomal recessive congenital ichthyosis."
Hum. Mutat. 26:351-361(2005) [PubMed] [Europe PMC] [Abstract]

"Molecular analysis of 250 patients with autosomal recessive congenital ichthyosis: evidence for mutation hotspots in ALOXE3 and allelic heterogeneity in ALOX12B."
J. Invest. Dermatol. 129:1421-1428(2009) [PubMed] [Europe PMC] [Abstract]

"Genotypic and clinical spectrum of self-improving collodion ichthyosis: ALOX12B, ALOXE3, and TGM1 mutations in Scandinavian patients."
J. Invest. Dermatol. 130:438-443(2010) [PubMed] [Europe PMC] [Abstract]