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Paraoxonase 3 (PON3)

Serum paraoxonase/lactonase 3

Members of the paraoxonase (EC 3.1.1.2) gene family, such as PON3, encode high density lipoprotein (HDL)-related glycoproteins with multienzymatic properties. (Lu et al., 2006).Lu et al. (2006) cloned PON3 from a fetal liver cDNA library. The deduced mature protein has 354 amino acids and a calculated molecular mass of 39.6 kD. It contains 3 cysteines that are conserved in PON1 and PON2. Cys41 and cys351 are predicted to form an intramolecular disulfide bond, and cys283 is predicted to be involved in antioxidant activity. Using nondenaturing PAGE, Draganov et al. (2005) observed native recombinant PON3 at an apparent molecular mass of 94.9 kD, suggesting that it probably forms dimers. Glycosidase treatment of human serum PON3 suggested that the secreted form of PON3 contains complex carbohydrates.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins T604Hu01 Recombinant Paraoxonase 3 (PON3) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Paraoxonase 3 (PON3) Bioactivity
Antibodies MT604Hu21 Monoclonal Antibody to Paraoxonase 3 (PON3) WB; IHC; ICC; IP.
PT604Hu01 Polyclonal Antibody to Paraoxonase 3 (PON3) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) Flow Cytometry;ICC/IF
Assay Kits KET604Hu ELISA Kit for Paraoxonase 3 (PON3) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Paraoxonase 3 (PON3) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Paraoxonase 3 (PON3) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Paraoxonase 3 (PON3) Bioactivity
Antibodies NONE Monoclonal Antibody to Paraoxonase 3 (PON3) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Paraoxonase 3 (PON3) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Paraoxonase 3 (PON3) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Paraoxonase 3 (PON3) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Paraoxonase 3 (PON3) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Paraoxonase 3 (PON3) Bioactivity
Antibodies NONE Monoclonal Antibody to Paraoxonase 3 (PON3) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Paraoxonase 3 (PON3) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Paraoxonase 3 (PON3) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Paraoxonase 3 (PON3) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Paraoxonase 3 (PON3) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Paraoxonase 3 (PON3) Bioactivity
Antibodies NONE Monoclonal Antibody to Paraoxonase 3 (PON3) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Paraoxonase 3 (PON3) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Paraoxonase 3 (PON3) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Paraoxonase 3 (PON3) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Paraoxonase 3 (PON3) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Paraoxonase 3 (PON3) Bioactivity
Antibodies NONE Monoclonal Antibody to Paraoxonase 3 (PON3) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Paraoxonase 3 (PON3) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Paraoxonase 3 (PON3) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Paraoxonase 3 (PON3) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Paraoxonase 3 (PON3) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Paraoxonase 3 (PON3) Bioactivity
Antibodies NONE Monoclonal Antibody to Paraoxonase 3 (PON3) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Paraoxonase 3 (PON3) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Paraoxonase 3 (PON3) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Paraoxonase 3 (PON3) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Paraoxonase 3 (PON3) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Paraoxonase 3 (PON3) Bioactivity
Antibodies NONE Monoclonal Antibody to Paraoxonase 3 (PON3) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Paraoxonase 3 (PON3) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Paraoxonase 3 (PON3) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Paraoxonase 3 (PON3) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Paraoxonase 3 (PON3) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Paraoxonase 3 (PON3) Bioactivity
Antibodies NONE Monoclonal Antibody to Paraoxonase 3 (PON3) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Paraoxonase 3 (PON3) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Paraoxonase 3 (PON3) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Paraoxonase 3 (PON3) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Paraoxonase 3 (PON3) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Paraoxonase 3 (PON3) Bioactivity
Antibodies NONE Monoclonal Antibody to Paraoxonase 3 (PON3) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Paraoxonase 3 (PON3) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Paraoxonase 3 (PON3) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Paraoxonase 3 (PON3) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Paraoxonase 3 (PON3) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Paraoxonase 3 (PON3) Bioactivity
Antibodies NONE Monoclonal Antibody to Paraoxonase 3 (PON3) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Paraoxonase 3 (PON3) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Paraoxonase 3 (PON3) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Paraoxonase 3 (PON3) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Paraoxonase 3 (PON3) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Paraoxonase 3 (PON3) Bioactivity
Antibodies NONE Monoclonal Antibody to Paraoxonase 3 (PON3) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Paraoxonase 3 (PON3) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Paraoxonase 3 (PON3) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Paraoxonase 3 (PON3) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Paraoxonase 3 (PON3) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Paraoxonase 3 (PON3) Bioactivity
Antibodies NONE Monoclonal Antibody to Paraoxonase 3 (PON3) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Paraoxonase 3 (PON3) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Paraoxonase 3 (PON3) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Paraoxonase 3 (PON3) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Paraoxonase 3 (PON3) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Paraoxonase 3 (PON3) Bioactivity
Antibodies NONE Monoclonal Antibody to Paraoxonase 3 (PON3) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Paraoxonase 3 (PON3) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Paraoxonase 3 (PON3) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Paraoxonase 3 (PON3) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Paraoxonase 3 (PON3) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Paraoxonase 3 (PON3) Bioactivity
Antibodies NONE Monoclonal Antibody to Paraoxonase 3 (PON3) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Paraoxonase 3 (PON3) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Paraoxonase 3 (PON3) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Paraoxonase 3 (PON3) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Paraoxonase 3 (PON3) CLIA assay for Antigen Detection

Reference

"Human chromosome 7: DNA sequence and biology."
Science 300:767-772(2003) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence of human chromosome 7."
Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"The human serum paraoxonase/arylesterase gene (PON1) is one member of a multigene family."
Genomics 33:498-507(1996) [PubMed] [Europe PMC] [Abstract]

"Human paraoxonases (PON1, PON2, and PON3) are lactonases with overlapping and distinct substrate specificities."
J. Lipid Res. 46:1239-1247(2005) [PubMed] [Europe PMC] [Abstract]

"Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."
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"Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]

"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]