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Ribonuclease A4 (RNASE4)
Ribonuclease A4 (RNASE4)
RNS4; Rnase-A4; Ribonuclease,RNase A Family 4
Rosenberg and Dyer (1995) referred to the protein as ribonuclease 4 (RNase4). By PCR analysis of human/hamster somatic cell hybrids, they determined that the gene encoding the protein resides in a single exon found on human chromosome 14.By Northern analysis, mRNA for the gene was detected in human pancreas, lung, skeletal muscle, heart, kidney, and placenta, but not brain; liver represented the most abundant source. The authors noted that the mRNA encoding this ribonuclease is approximately 2 kb in length, or approximately twice as long as the mRNAs encoding other members of this gene family. They also detected a larger (approximately 2.4 kb), second transcript in hepatic, pancreatic and renal tissues. At the time of creation of this entry, 1 other protein had the name ribonuclease 4: RNS4, which is located on chromosome 1
Organism species: Homo sapiens (Human)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
T592Hu01
Recombinant Ribonuclease A4 (RNASE4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Ribonuclease A4 (RNASE4) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Ribonuclease A4 (RNASE4) WB; IHC; ICC; IP.
PT592Hu01
Polyclonal Antibody to Ribonuclease A4 (RNASE4) WB; IHC; ICC; IF.
LT592Hu71
Biotin Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Ribonuclease A4 (RNASE4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Ribonuclease A4 (RNASE4) CLIA assay for Antigen Detection
Organism species: Mus musculus (Mouse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Ribonuclease A4 (RNASE4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Ribonuclease A4 (RNASE4) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Ribonuclease A4 (RNASE4) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Ribonuclease A4 (RNASE4) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Ribonuclease A4 (RNASE4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Ribonuclease A4 (RNASE4) CLIA assay for Antigen Detection
Organism species: Rattus norvegicus (Rat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Ribonuclease A4 (RNASE4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Ribonuclease A4 (RNASE4) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Ribonuclease A4 (RNASE4) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Ribonuclease A4 (RNASE4) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Ribonuclease A4 (RNASE4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Ribonuclease A4 (RNASE4) CLIA assay for Antigen Detection
Organism species: Canis familiaris; Canine (Dog)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Ribonuclease A4 (RNASE4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Ribonuclease A4 (RNASE4) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Ribonuclease A4 (RNASE4) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Ribonuclease A4 (RNASE4) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Ribonuclease A4 (RNASE4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Ribonuclease A4 (RNASE4) CLIA assay for Antigen Detection
Organism species: Sus scrofa; Porcine (Pig)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Ribonuclease A4 (RNASE4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Ribonuclease A4 (RNASE4) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Ribonuclease A4 (RNASE4) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Ribonuclease A4 (RNASE4) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Ribonuclease A4 (RNASE4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Ribonuclease A4 (RNASE4) CLIA assay for Antigen Detection
Organism species: Bos taurus; Bovine (Cattle)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Ribonuclease A4 (RNASE4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Ribonuclease A4 (RNASE4) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Ribonuclease A4 (RNASE4) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Ribonuclease A4 (RNASE4) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Ribonuclease A4 (RNASE4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Ribonuclease A4 (RNASE4) CLIA assay for Antigen Detection
Organism species: Rhesus monkey (Simian)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Ribonuclease A4 (RNASE4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Ribonuclease A4 (RNASE4) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Ribonuclease A4 (RNASE4) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Ribonuclease A4 (RNASE4) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Ribonuclease A4 (RNASE4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Ribonuclease A4 (RNASE4) CLIA assay for Antigen Detection
Organism species: Chicken (Gallus)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Ribonuclease A4 (RNASE4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Ribonuclease A4 (RNASE4) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Ribonuclease A4 (RNASE4) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Ribonuclease A4 (RNASE4) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Ribonuclease A4 (RNASE4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Ribonuclease A4 (RNASE4) CLIA assay for Antigen Detection
Organism species: Ovis aries; Ovine (Sheep)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Ribonuclease A4 (RNASE4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Ribonuclease A4 (RNASE4) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Ribonuclease A4 (RNASE4) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Ribonuclease A4 (RNASE4) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Ribonuclease A4 (RNASE4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Ribonuclease A4 (RNASE4) CLIA assay for Antigen Detection
Organism species: Oryctolagus cuniculus (Rabbit)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Ribonuclease A4 (RNASE4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Ribonuclease A4 (RNASE4) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Ribonuclease A4 (RNASE4) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Ribonuclease A4 (RNASE4) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Ribonuclease A4 (RNASE4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Ribonuclease A4 (RNASE4) CLIA assay for Antigen Detection
Organism species: Cavia (Guinea pig )
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Ribonuclease A4 (RNASE4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Ribonuclease A4 (RNASE4) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Ribonuclease A4 (RNASE4) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Ribonuclease A4 (RNASE4) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Ribonuclease A4 (RNASE4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Ribonuclease A4 (RNASE4) CLIA assay for Antigen Detection
Organism species: Equus caballus; Equine (Horse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Ribonuclease A4 (RNASE4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Ribonuclease A4 (RNASE4) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Ribonuclease A4 (RNASE4) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Ribonuclease A4 (RNASE4) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Ribonuclease A4 (RNASE4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Ribonuclease A4 (RNASE4) CLIA assay for Antigen Detection
Organism species: Capra hircus; Caprine (Goat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Ribonuclease A4 (RNASE4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Ribonuclease A4 (RNASE4) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Ribonuclease A4 (RNASE4) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Ribonuclease A4 (RNASE4) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Ribonuclease A4 (RNASE4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Ribonuclease A4 (RNASE4) CLIA assay for Antigen Detection
Organism species: Pan-species (General)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Ribonuclease A4 (RNASE4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Ribonuclease A4 (RNASE4) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Ribonuclease A4 (RNASE4) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Ribonuclease A4 (RNASE4) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Ribonuclease A4 (RNASE4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Ribonuclease A4 (RNASE4) CLIA assay for Antigen Detection
Reference
"Molecular cloning and expression of human ribonuclease 4 cDNA." Biochim. Biophys. Acta 1261:424-426(1995) [PubMed ] [Europe PMC ] [Abstract ]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." Genome Res. 14:2121-2127(2004) [PubMed ] [Europe PMC ] [Abstract ]
"Human ribonuclease 4 (RNase 4): coding sequence, chromosomal localization and identification of two distinct transcripts in human somatic tissues." Nucleic Acids Res. 23:4290-4295(1995) [PubMed ] [Europe PMC ] [Abstract ]
"The amino acid sequence of human ribonuclease 4, a highly conserved ribonuclease that cleaves specifically on the 3' side of uridine." Eur. J. Biochem. 217:401-410(1993) [PubMed ] [Europe PMC ] [Abstract ]
"Isolation and characterization of a human colon carcinoma-secreted enzyme with pancreatic ribonuclease-like activity." Biochemistry 25:7255-7264(1986) [PubMed ] [Europe PMC ] [Abstract ]
"The three-dimensional structure of human RNase 4, unliganded and complexed with d(Up), reveals the basis for its uridine selectivity." J. Mol. Biol. 285:205-214(1999) [PubMed ] [Europe PMC ] [Abstract ]