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Ribonuclease A4 (RNASE4)

RNS4; Rnase-A4; Ribonuclease,RNase A Family 4

Rosenberg and Dyer (1995) referred to the protein as ribonuclease 4 (RNase4). By PCR analysis of human/hamster somatic cell hybrids, they determined that the gene encoding the protein resides in a single exon found on human chromosome 14.By Northern analysis, mRNA for the gene was detected in human pancreas, lung, skeletal muscle, heart, kidney, and placenta, but not brain; liver represented the most abundant source. The authors noted that the mRNA encoding this ribonuclease is approximately 2 kb in length, or approximately twice as long as the mRNAs encoding other members of this gene family. They also detected a larger (approximately 2.4 kb), second transcript in hepatic, pancreatic and renal tissues. At the time of creation of this entry, 1 other protein had the name ribonuclease 4: RNS4, which is located on chromosome 1

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins T592Hu01 Recombinant Ribonuclease A4 (RNASE4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ribonuclease A4 (RNASE4) Bioactivity
Antibodies NONE Monoclonal Antibody to Ribonuclease A4 (RNASE4) WB; IHC; ICC; IP.
PT592Hu01 Polyclonal Antibody to Ribonuclease A4 (RNASE4) WB; IHC; ICC; IF.
LT592Hu71 Biotin Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Ribonuclease A4 (RNASE4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ribonuclease A4 (RNASE4) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Ribonuclease A4 (RNASE4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ribonuclease A4 (RNASE4) Bioactivity
Antibodies NONE Monoclonal Antibody to Ribonuclease A4 (RNASE4) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Ribonuclease A4 (RNASE4) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Ribonuclease A4 (RNASE4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ribonuclease A4 (RNASE4) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Ribonuclease A4 (RNASE4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ribonuclease A4 (RNASE4) Bioactivity
Antibodies NONE Monoclonal Antibody to Ribonuclease A4 (RNASE4) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Ribonuclease A4 (RNASE4) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Ribonuclease A4 (RNASE4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ribonuclease A4 (RNASE4) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Ribonuclease A4 (RNASE4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ribonuclease A4 (RNASE4) Bioactivity
Antibodies NONE Monoclonal Antibody to Ribonuclease A4 (RNASE4) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Ribonuclease A4 (RNASE4) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Ribonuclease A4 (RNASE4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ribonuclease A4 (RNASE4) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Ribonuclease A4 (RNASE4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ribonuclease A4 (RNASE4) Bioactivity
Antibodies NONE Monoclonal Antibody to Ribonuclease A4 (RNASE4) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Ribonuclease A4 (RNASE4) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Ribonuclease A4 (RNASE4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ribonuclease A4 (RNASE4) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Ribonuclease A4 (RNASE4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ribonuclease A4 (RNASE4) Bioactivity
Antibodies NONE Monoclonal Antibody to Ribonuclease A4 (RNASE4) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Ribonuclease A4 (RNASE4) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Ribonuclease A4 (RNASE4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ribonuclease A4 (RNASE4) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Ribonuclease A4 (RNASE4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ribonuclease A4 (RNASE4) Bioactivity
Antibodies NONE Monoclonal Antibody to Ribonuclease A4 (RNASE4) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Ribonuclease A4 (RNASE4) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Ribonuclease A4 (RNASE4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ribonuclease A4 (RNASE4) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Ribonuclease A4 (RNASE4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ribonuclease A4 (RNASE4) Bioactivity
Antibodies NONE Monoclonal Antibody to Ribonuclease A4 (RNASE4) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Ribonuclease A4 (RNASE4) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Ribonuclease A4 (RNASE4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ribonuclease A4 (RNASE4) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Ribonuclease A4 (RNASE4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ribonuclease A4 (RNASE4) Bioactivity
Antibodies NONE Monoclonal Antibody to Ribonuclease A4 (RNASE4) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Ribonuclease A4 (RNASE4) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Ribonuclease A4 (RNASE4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ribonuclease A4 (RNASE4) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Ribonuclease A4 (RNASE4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ribonuclease A4 (RNASE4) Bioactivity
Antibodies NONE Monoclonal Antibody to Ribonuclease A4 (RNASE4) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Ribonuclease A4 (RNASE4) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Ribonuclease A4 (RNASE4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ribonuclease A4 (RNASE4) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Ribonuclease A4 (RNASE4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ribonuclease A4 (RNASE4) Bioactivity
Antibodies NONE Monoclonal Antibody to Ribonuclease A4 (RNASE4) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Ribonuclease A4 (RNASE4) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Ribonuclease A4 (RNASE4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ribonuclease A4 (RNASE4) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Ribonuclease A4 (RNASE4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ribonuclease A4 (RNASE4) Bioactivity
Antibodies NONE Monoclonal Antibody to Ribonuclease A4 (RNASE4) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Ribonuclease A4 (RNASE4) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Ribonuclease A4 (RNASE4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ribonuclease A4 (RNASE4) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Ribonuclease A4 (RNASE4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ribonuclease A4 (RNASE4) Bioactivity
Antibodies NONE Monoclonal Antibody to Ribonuclease A4 (RNASE4) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Ribonuclease A4 (RNASE4) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Ribonuclease A4 (RNASE4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ribonuclease A4 (RNASE4) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Ribonuclease A4 (RNASE4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Ribonuclease A4 (RNASE4) Bioactivity
Antibodies NONE Monoclonal Antibody to Ribonuclease A4 (RNASE4) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Ribonuclease A4 (RNASE4) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Ribonuclease A4 (RNASE4) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Ribonuclease A4 (RNASE4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Ribonuclease A4 (RNASE4) CLIA assay for Antigen Detection

Reference

"Molecular cloning and expression of human ribonuclease 4 cDNA."
Biochim. Biophys. Acta 1261:424-426(1995) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Human ribonuclease 4 (RNase 4): coding sequence, chromosomal localization and identification of two distinct transcripts in human somatic tissues."
Nucleic Acids Res. 23:4290-4295(1995) [PubMed] [Europe PMC] [Abstract]

"The amino acid sequence of human ribonuclease 4, a highly conserved ribonuclease that cleaves specifically on the 3' side of uridine."
Eur. J. Biochem. 217:401-410(1993) [PubMed] [Europe PMC] [Abstract]

"Isolation and characterization of a human colon carcinoma-secreted enzyme with pancreatic ribonuclease-like activity."
Biochemistry 25:7255-7264(1986) [PubMed] [Europe PMC] [Abstract]

"The three-dimensional structure of human RNase 4, unliganded and complexed with d(Up), reveals the basis for its uridine selectivity."
J. Mol. Biol. 285:205-214(1999) [PubMed] [Europe PMC] [Abstract]