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Ribonuclease A7 (RNASE7)
Ribonuclease A7 (RNASE7)
SAP-2; Rnase-A7; Ribonuclease,RNase A Family 7; Skin-derived antimicrobial protein 2
RNASE7 is a member of the RNase A superfamily that has broad-spectrum antimicrobial activity and ribonuclease activity .Harder and Schroder showed that recombinant RNASE7 displayed catalytic activity against yeast tRNA. They found that RNASE7 exhibited broad-spectrum antimicrobial activity against several gram-positive and gram-negative bacteria, and against Candida albicans, as well as vancomycin-resistant E. faecium. RNASE7 expression was induced upon treatment with interferon gamma, interleukin-1-beta, and to a lesser extent by TNF-alpha. Zhang et al. also identified broad spectrum RNASE7 antimicrobial activity. However, they determined that RNASE7 did not display antiviral activity against respiratory syncytial virus infectivity for human epithelium cells using an in vitro assay. They confirmed that recombinant RNASE7 displayed catalytic activity against yeast tRNA.
Organism species: Homo sapiens (Human)
Organism species: Mus musculus (Mouse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Ribonuclease A7 (RNASE7) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Ribonuclease A7 (RNASE7) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Ribonuclease A7 (RNASE7) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Ribonuclease A7 (RNASE7) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Ribonuclease A7 (RNASE7) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Ribonuclease A7 (RNASE7) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Ribonuclease A7 (RNASE7) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Ribonuclease A7 (RNASE7) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Ribonuclease A7 (RNASE7) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Ribonuclease A7 (RNASE7) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Ribonuclease A7 (RNASE7) CLIA assay for Antigen Detection
Organism species: Rattus norvegicus (Rat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Ribonuclease A7 (RNASE7) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Ribonuclease A7 (RNASE7) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Ribonuclease A7 (RNASE7) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Ribonuclease A7 (RNASE7) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Ribonuclease A7 (RNASE7) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Ribonuclease A7 (RNASE7) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Ribonuclease A7 (RNASE7) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Ribonuclease A7 (RNASE7) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Ribonuclease A7 (RNASE7) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Ribonuclease A7 (RNASE7) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Ribonuclease A7 (RNASE7) CLIA assay for Antigen Detection
Organism species: Canis familiaris; Canine (Dog)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Ribonuclease A7 (RNASE7) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Ribonuclease A7 (RNASE7) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Ribonuclease A7 (RNASE7) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Ribonuclease A7 (RNASE7) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Ribonuclease A7 (RNASE7) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Ribonuclease A7 (RNASE7) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Ribonuclease A7 (RNASE7) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Ribonuclease A7 (RNASE7) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Ribonuclease A7 (RNASE7) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Ribonuclease A7 (RNASE7) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Ribonuclease A7 (RNASE7) CLIA assay for Antigen Detection
Organism species: Sus scrofa; Porcine (Pig)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Ribonuclease A7 (RNASE7) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Ribonuclease A7 (RNASE7) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Ribonuclease A7 (RNASE7) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Ribonuclease A7 (RNASE7) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Ribonuclease A7 (RNASE7) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Ribonuclease A7 (RNASE7) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Ribonuclease A7 (RNASE7) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Ribonuclease A7 (RNASE7) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Ribonuclease A7 (RNASE7) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Ribonuclease A7 (RNASE7) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Ribonuclease A7 (RNASE7) CLIA assay for Antigen Detection
Organism species: Bos taurus; Bovine (Cattle)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Ribonuclease A7 (RNASE7) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Ribonuclease A7 (RNASE7) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Ribonuclease A7 (RNASE7) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Ribonuclease A7 (RNASE7) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Ribonuclease A7 (RNASE7) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Ribonuclease A7 (RNASE7) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Ribonuclease A7 (RNASE7) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Ribonuclease A7 (RNASE7) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Ribonuclease A7 (RNASE7) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Ribonuclease A7 (RNASE7) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Ribonuclease A7 (RNASE7) CLIA assay for Antigen Detection
Organism species: Rhesus monkey (Simian)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Ribonuclease A7 (RNASE7) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Ribonuclease A7 (RNASE7) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Ribonuclease A7 (RNASE7) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Ribonuclease A7 (RNASE7) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Ribonuclease A7 (RNASE7) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Ribonuclease A7 (RNASE7) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Ribonuclease A7 (RNASE7) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Ribonuclease A7 (RNASE7) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Ribonuclease A7 (RNASE7) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Ribonuclease A7 (RNASE7) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Ribonuclease A7 (RNASE7) CLIA assay for Antigen Detection
Organism species: Chicken (Gallus)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Ribonuclease A7 (RNASE7) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Ribonuclease A7 (RNASE7) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Ribonuclease A7 (RNASE7) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Ribonuclease A7 (RNASE7) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Ribonuclease A7 (RNASE7) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Ribonuclease A7 (RNASE7) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Ribonuclease A7 (RNASE7) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Ribonuclease A7 (RNASE7) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Ribonuclease A7 (RNASE7) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Ribonuclease A7 (RNASE7) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Ribonuclease A7 (RNASE7) CLIA assay for Antigen Detection
Organism species: Ovis aries; Ovine (Sheep)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Ribonuclease A7 (RNASE7) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Ribonuclease A7 (RNASE7) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Ribonuclease A7 (RNASE7) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Ribonuclease A7 (RNASE7) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Ribonuclease A7 (RNASE7) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Ribonuclease A7 (RNASE7) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Ribonuclease A7 (RNASE7) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Ribonuclease A7 (RNASE7) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Ribonuclease A7 (RNASE7) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Ribonuclease A7 (RNASE7) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Ribonuclease A7 (RNASE7) CLIA assay for Antigen Detection
Organism species: Oryctolagus cuniculus (Rabbit)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Ribonuclease A7 (RNASE7) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Ribonuclease A7 (RNASE7) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Ribonuclease A7 (RNASE7) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Ribonuclease A7 (RNASE7) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Ribonuclease A7 (RNASE7) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Ribonuclease A7 (RNASE7) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Ribonuclease A7 (RNASE7) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Ribonuclease A7 (RNASE7) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Ribonuclease A7 (RNASE7) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Ribonuclease A7 (RNASE7) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Ribonuclease A7 (RNASE7) CLIA assay for Antigen Detection
Organism species: Cavia (Guinea pig )
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Ribonuclease A7 (RNASE7) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Ribonuclease A7 (RNASE7) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Ribonuclease A7 (RNASE7) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Ribonuclease A7 (RNASE7) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Ribonuclease A7 (RNASE7) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Ribonuclease A7 (RNASE7) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Ribonuclease A7 (RNASE7) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Ribonuclease A7 (RNASE7) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Ribonuclease A7 (RNASE7) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Ribonuclease A7 (RNASE7) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Ribonuclease A7 (RNASE7) CLIA assay for Antigen Detection
Organism species: Equus caballus; Equine (Horse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Ribonuclease A7 (RNASE7) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Ribonuclease A7 (RNASE7) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Ribonuclease A7 (RNASE7) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Ribonuclease A7 (RNASE7) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Ribonuclease A7 (RNASE7) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Ribonuclease A7 (RNASE7) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Ribonuclease A7 (RNASE7) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Ribonuclease A7 (RNASE7) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Ribonuclease A7 (RNASE7) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Ribonuclease A7 (RNASE7) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Ribonuclease A7 (RNASE7) CLIA assay for Antigen Detection
Organism species: Capra hircus; Caprine (Goat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Ribonuclease A7 (RNASE7) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Ribonuclease A7 (RNASE7) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Ribonuclease A7 (RNASE7) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Ribonuclease A7 (RNASE7) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Ribonuclease A7 (RNASE7) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Ribonuclease A7 (RNASE7) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Ribonuclease A7 (RNASE7) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Ribonuclease A7 (RNASE7) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Ribonuclease A7 (RNASE7) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Ribonuclease A7 (RNASE7) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Ribonuclease A7 (RNASE7) CLIA assay for Antigen Detection
Organism species: Pan-species (General)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Ribonuclease A7 (RNASE7) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Ribonuclease A7 (RNASE7) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Ribonuclease A7 (RNASE7) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Ribonuclease A7 (RNASE7) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Ribonuclease A7 (RNASE7) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Ribonuclease A7 (RNASE7) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Ribonuclease A7 (RNASE7) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Ribonuclease A7 (RNASE7) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Ribonuclease A7 (RNASE7) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Ribonuclease A7 (RNASE7) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Ribonuclease A7 (RNASE7) CLIA assay for Antigen Detection
Reference
"RNase 7, a novel innate immune defense antimicrobial protein of healthy human skin." J. Biol. Chem. 277:46779-46784(2002) [PubMed ] [Europe PMC ] [Abstract ]
"Human RNase 7: a new cationic ribonuclease of the RNase A superfamily." Nucleic Acids Res. 31:602-607(2003) [PubMed ] [Europe PMC ] [Abstract ]
"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed ] [Europe PMC ] [Abstract ]
"The DNA sequence and analysis of human chromosome 14." Nature 421:601-607(2003) [PubMed ] [Europe PMC ] [Abstract ]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." Genome Res. 14:2121-2127(2004) [PubMed ] [Europe PMC ] [Abstract ]
, Submitted (MAR-1997) to UniProtKB
"The flexible and clustered lysine residues of human ribonuclease 7 are critical for membrane permeability and antimicrobial activity." J. Biol. Chem. 282:4626-4633(2007) [PubMed ] [Europe PMC ] [Abstract ]
