Epstein Barr Virus Induced Protein 3 (EBI3)
IL27B; IL27-B; Interleukin 27B; Epstein-Barr virus-induced gene 3 protein; EBV-induced gene 3 protein
Epstein-Barr virus induced gene 3was identified by the induction of its expression in B lymphocytes by Epstein-Barr virus infection. The protein encoded by this gene is a secreted glycoprotein, which is a member of the hematopoietin receptor family related to the p40 subunit of interleukin 12 (IL-12). It plays a role in regulating cell-mediated immune responses.EBI3 is a subunit in 2 distinct heterodimeric cytokines: interleukin-27 (IL27) and IL35.
IL27 is composed of p28 (IL27) and EBI3. IL27 can trigger signaling in T cells, B cells, and myeloid cells. IL35, an inhibitory cytokine involved in regulatory T-cell function, is composed of EBI3 and the p35 subunit of IL12.Interleukin-27 (IL-27)is composed of two subunits, Epstein-Barr virus (EBV)-induced gene 3 (EBI3) (IL-27B) and IL27-p28 (known as IL-30).
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT574Hu01 | Recombinant Epstein Barr Virus Induced Protein 3 (EBI3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT574Hu01 | Monoclonal Antibody to Epstein Barr Virus Induced Protein 3 (EBI3) | WB; IHC; ICC; IP. |
| PAT574Hu01 | Polyclonal Antibody to Epstein Barr Virus Induced Protein 3 (EBI3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT574Hu01 | CLIA Kit for Epstein Barr Virus Induced Protein 3 (EBI3) | CLIA assay for Antigen Detection |
| ELT574Hu01 | ELISA Kit for Epstein Barr Virus Induced Protein 3 (EBI3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT574Mu01 | Recombinant Epstein Barr Virus Induced Protein 3 (EBI3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT574Mu01 | Monoclonal Antibody to Epstein Barr Virus Induced Protein 3 (EBI3) | WB; IHC; ICC; IP. |
| PAT574Mu01 | Polyclonal Antibody to Epstein Barr Virus Induced Protein 3 (EBI3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT574Mu01 | CLIA Kit for Epstein Barr Virus Induced Protein 3 (EBI3) | CLIA assay for Antigen Detection |
| ELT574Mu01 | ELISA Kit for Epstein Barr Virus Induced Protein 3 (EBI3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT574Ra01 | Recombinant Epstein Barr Virus Induced Protein 3 (EBI3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT574Ra01 | Monoclonal Antibody to Epstein Barr Virus Induced Protein 3 (EBI3) | WB; IHC; ICC; IP. |
| PAT574Ra01 | Polyclonal Antibody to Epstein Barr Virus Induced Protein 3 (EBI3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT574Ra01 | CLIA Kit for Epstein Barr Virus Induced Protein 3 (EBI3) | CLIA assay for Antigen Detection |
| ELT574Ra01 | ELISA Kit for Epstein Barr Virus Induced Protein 3 (EBI3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT574Ca01 | Recombinant Epstein Barr Virus Induced Protein 3 (EBI3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT574Ca01 | Monoclonal Antibody to Epstein Barr Virus Induced Protein 3 (EBI3) | WB; IHC; ICC; IP. |
| PAT574Ca01 | Polyclonal Antibody to Epstein Barr Virus Induced Protein 3 (EBI3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT574Ca01 | CLIA Kit for Epstein Barr Virus Induced Protein 3 (EBI3) | CLIA assay for Antigen Detection |
| ELT574Ca01 | ELISA Kit for Epstein Barr Virus Induced Protein 3 (EBI3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT574Po01 | Recombinant Epstein Barr Virus Induced Protein 3 (EBI3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT574Po01 | Monoclonal Antibody to Epstein Barr Virus Induced Protein 3 (EBI3) | WB; IHC; ICC; IP. |
| PAT574Po01 | Polyclonal Antibody to Epstein Barr Virus Induced Protein 3 (EBI3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT574Po01 | CLIA Kit for Epstein Barr Virus Induced Protein 3 (EBI3) | CLIA assay for Antigen Detection |
| ELT574Po01 | ELISA Kit for Epstein Barr Virus Induced Protein 3 (EBI3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT574Bo01 | Recombinant Epstein Barr Virus Induced Protein 3 (EBI3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT574Bo01 | Monoclonal Antibody to Epstein Barr Virus Induced Protein 3 (EBI3) | WB; IHC; ICC; IP. |
| PAT574Bo01 | Polyclonal Antibody to Epstein Barr Virus Induced Protein 3 (EBI3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT574Bo01 | CLIA Kit for Epstein Barr Virus Induced Protein 3 (EBI3) | CLIA assay for Antigen Detection |
| ELT574Bo01 | ELISA Kit for Epstein Barr Virus Induced Protein 3 (EBI3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT574Rb01 | Recombinant Epstein Barr Virus Induced Protein 3 (EBI3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT574Rb01 | Monoclonal Antibody to Epstein Barr Virus Induced Protein 3 (EBI3) | WB; IHC; ICC; IP. |
| PAT574Rb01 | Polyclonal Antibody to Epstein Barr Virus Induced Protein 3 (EBI3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT574Rb01 | CLIA Kit for Epstein Barr Virus Induced Protein 3 (EBI3) | CLIA assay for Antigen Detection |
| ELT574Rb01 | ELISA Kit for Epstein Barr Virus Induced Protein 3 (EBI3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT574Mo01 | Recombinant Epstein Barr Virus Induced Protein 3 (EBI3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT574Mo01 | Monoclonal Antibody to Epstein Barr Virus Induced Protein 3 (EBI3) | WB; IHC; ICC; IP. |
| PAT574Mo01 | Polyclonal Antibody to Epstein Barr Virus Induced Protein 3 (EBI3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT574Mo01 | CLIA Kit for Epstein Barr Virus Induced Protein 3 (EBI3) | CLIA assay for Antigen Detection |
| ELT574Mo01 | ELISA Kit for Epstein Barr Virus Induced Protein 3 (EBI3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"A novel interleukin-12 p40-related protein induced by latent Epstein-Barr virus infection in B lymphocytes."
J. Virol. 70:1143-1153(1996) [PubMed] [Europe PMC] [Abstract]
"The DNA sequence and biology of human chromosome 19."
Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Epstein-Barr virus-induced gene 3 and the p35 subunit of interleukin 12 form a novel heterodimeric hematopoietin."
Proc. Natl. Acad. Sci. U.S.A. 94:12041-12046(1997) [PubMed] [Europe PMC] [Abstract]
"IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4(+) T cells."
Immunity 16:779-790(2002) [PubMed] [Europe PMC] [Abstract]
"The biology and therapeutic potential of interleukin 27."
J. Mol. Med. 85:661-672(2007) [PubMed] [Europe PMC] [Abstract]