Troponin T Type 3, Fast Skeletal (TNNT3)
AMCD2B; DA2B; FSSV; fTnT; Troponin T3; Beta-TnTF; Fast skeletal muscle troponin T
Subunit T binds the troponin complex to the tropomyosin complex and is also required for Ca(2+)-mediated activation of actomyosin ATPase activity. There are 3 different troponin T genes that encode tissue-specific isoforms of subunit T for fast skeletal-, slow skeletal-, and cardiac-muscle. This gene encodes fast skeletal troponin T protein; also known as troponin T type 3. Alternative splicing results in multiple transcript variants encoding additional distinct troponin T type 3 isoforms. A developmentally regulated switch between fetal/neonatal and adult troponin T type 3 isoforms occurs. Additional splice variants have been described but their biological validity has not been established. Mutations in this gene may cause distal arthrogryposis multiplex congenita type 2B (DA2B).
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT548Hu01 | Recombinant Troponin T Type 3, Fast Skeletal (TNNT3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT548Hu01 | Monoclonal Antibody to Troponin T Type 3, Fast Skeletal (TNNT3) | WB; IHC; ICC; IP. |
| PAT548Hu01 | Polyclonal Antibody to Troponin T Type 3, Fast Skeletal (TNNT3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT548Hu01 | CLIA Kit for Troponin T Type 3, Fast Skeletal (TNNT3) | CLIA assay for Antigen Detection |
| ELT548Hu01 | ELISA Kit for Troponin T Type 3, Fast Skeletal (TNNT3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT548Mu01 | Recombinant Troponin T Type 3, Fast Skeletal (TNNT3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT548Mu01 | Monoclonal Antibody to Troponin T Type 3, Fast Skeletal (TNNT3) | WB; IHC; ICC; IP. |
| PAT548Mu01 | Polyclonal Antibody to Troponin T Type 3, Fast Skeletal (TNNT3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT548Mu01 | CLIA Kit for Troponin T Type 3, Fast Skeletal (TNNT3) | CLIA assay for Antigen Detection |
| ELT548Mu01 | ELISA Kit for Troponin T Type 3, Fast Skeletal (TNNT3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT548Ra01 | Recombinant Troponin T Type 3, Fast Skeletal (TNNT3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT548Ra01 | Monoclonal Antibody to Troponin T Type 3, Fast Skeletal (TNNT3) | WB; IHC; ICC; IP. |
| PAT548Ra01 | Polyclonal Antibody to Troponin T Type 3, Fast Skeletal (TNNT3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT548Ra01 | CLIA Kit for Troponin T Type 3, Fast Skeletal (TNNT3) | CLIA assay for Antigen Detection |
| ELT548Ra01 | ELISA Kit for Troponin T Type 3, Fast Skeletal (TNNT3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT548Ca01 | Recombinant Troponin T Type 3, Fast Skeletal (TNNT3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT548Ca01 | Monoclonal Antibody to Troponin T Type 3, Fast Skeletal (TNNT3) | WB; IHC; ICC; IP. |
| PAT548Ca01 | Polyclonal Antibody to Troponin T Type 3, Fast Skeletal (TNNT3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT548Ca01 | CLIA Kit for Troponin T Type 3, Fast Skeletal (TNNT3) | CLIA assay for Antigen Detection |
| ELT548Ca01 | ELISA Kit for Troponin T Type 3, Fast Skeletal (TNNT3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT548Po01 | Recombinant Troponin T Type 3, Fast Skeletal (TNNT3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT548Po01 | Monoclonal Antibody to Troponin T Type 3, Fast Skeletal (TNNT3) | WB; IHC; ICC; IP. |
| PAT548Po01 | Polyclonal Antibody to Troponin T Type 3, Fast Skeletal (TNNT3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT548Po01 | CLIA Kit for Troponin T Type 3, Fast Skeletal (TNNT3) | CLIA assay for Antigen Detection |
| ELT548Po01 | ELISA Kit for Troponin T Type 3, Fast Skeletal (TNNT3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT548Bo01 | Recombinant Troponin T Type 3, Fast Skeletal (TNNT3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT548Bo01 | Monoclonal Antibody to Troponin T Type 3, Fast Skeletal (TNNT3) | WB; IHC; ICC; IP. |
| PAT548Bo01 | Polyclonal Antibody to Troponin T Type 3, Fast Skeletal (TNNT3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT548Bo01 | CLIA Kit for Troponin T Type 3, Fast Skeletal (TNNT3) | CLIA assay for Antigen Detection |
| ELT548Bo01 | ELISA Kit for Troponin T Type 3, Fast Skeletal (TNNT3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT548Rb01 | Recombinant Troponin T Type 3, Fast Skeletal (TNNT3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT548Rb01 | Monoclonal Antibody to Troponin T Type 3, Fast Skeletal (TNNT3) | WB; IHC; ICC; IP. |
| PAT548Rb01 | Polyclonal Antibody to Troponin T Type 3, Fast Skeletal (TNNT3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT548Rb01 | CLIA Kit for Troponin T Type 3, Fast Skeletal (TNNT3) | CLIA assay for Antigen Detection |
| ELT548Rb01 | ELISA Kit for Troponin T Type 3, Fast Skeletal (TNNT3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT548Mo01 | Recombinant Troponin T Type 3, Fast Skeletal (TNNT3) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT548Mo01 | Monoclonal Antibody to Troponin T Type 3, Fast Skeletal (TNNT3) | WB; IHC; ICC; IP. |
| PAT548Mo01 | Polyclonal Antibody to Troponin T Type 3, Fast Skeletal (TNNT3) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT548Mo01 | CLIA Kit for Troponin T Type 3, Fast Skeletal (TNNT3) | CLIA assay for Antigen Detection |
| ELT548Mo01 | ELISA Kit for Troponin T Type 3, Fast Skeletal (TNNT3) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
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DNA Cell Biol. 13:217-233(1994) [PubMed] [Europe PMC] [Abstract]
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
"The full-ORF clone resource of the German cDNA consortium."
BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
"Human chromosome 11 DNA sequence and analysis including novel gene identification."
Nature 440:497-500(2006) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Identification of a fetal exon in the human fast troponin T gene."
FEBS Lett. 350:37-40(1994) [PubMed] [Europe PMC] [Abstract]
"Mutations in TNNT3 cause multiple congenital contractures: a second locus for distal arthrogryposis type 2B."
Am. J. Hum. Genet. 73:212-214(2003) [PubMed] [Europe PMC] [Abstract]