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Cyclin Y (CCNY)

CCN-Y; CFP1; CBCP1; Cyclin box protein 1; Cyclin fold protein 1; cyclin-X

Cyclins, such as CCNY, control cell division cycles and regulate cyclin-dependent kinases By database analysis and PCR of a testis cDNA library.The deduced 287-amino acid protein has a central cyclin box and shares highest similarity with cyclin B3 (CCNB3). RT-PCR detected highest expression in testis and lower expression in all other tissues examined except brain and kidney. Fluorescence-tagged CCNX was expressed predominantly in the nucleus in a human nonsmall lung cancer cell line.Using mass spectrometry to identify proteins upregulated in metastatic versus nonmetastatic human colorectal adenocarcinoma cell lines, followed by database analysis, Zhang et al. (2005) identified an isoform of CCNY that they called CFP1 variant A. The deduced protein has a calculated molecular mass of 36.9 kD.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cyclin Y (CCNY) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cyclin Y (CCNY) Bioactivity
Antibodies MT511Hu21 Monoclonal Antibody to Cyclin Y (CCNY) WB; IHC; ICC; IP.
PT511Hu01 Polyclonal Antibody to Cyclin Y (CCNY) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cyclin Y (CCNY) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cyclin Y (CCNY) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cyclin Y (CCNY) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cyclin Y (CCNY) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cyclin Y (CCNY) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cyclin Y (CCNY) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cyclin Y (CCNY) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cyclin Y (CCNY) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cyclin Y (CCNY) Bioactivity
Antibodies NONE Monoclonal Antibody to Cyclin Y (CCNY) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cyclin Y (CCNY) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cyclin Y (CCNY) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cyclin Y (CCNY) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cyclin Y (CCNY) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cyclin Y (CCNY) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cyclin Y (CCNY) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cyclin Y (CCNY) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cyclin Y (CCNY) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cyclin Y (CCNY) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cyclin Y (CCNY) Bioactivity
Antibodies NONE Monoclonal Antibody to Cyclin Y (CCNY) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cyclin Y (CCNY) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cyclin Y (CCNY) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cyclin Y (CCNY) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cyclin Y (CCNY) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cyclin Y (CCNY) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cyclin Y (CCNY) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cyclin Y (CCNY) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cyclin Y (CCNY) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cyclin Y (CCNY) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cyclin Y (CCNY) Bioactivity
Antibodies NONE Monoclonal Antibody to Cyclin Y (CCNY) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cyclin Y (CCNY) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cyclin Y (CCNY) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cyclin Y (CCNY) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cyclin Y (CCNY) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cyclin Y (CCNY) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cyclin Y (CCNY) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cyclin Y (CCNY) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cyclin Y (CCNY) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cyclin Y (CCNY) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cyclin Y (CCNY) Bioactivity
Antibodies NONE Monoclonal Antibody to Cyclin Y (CCNY) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cyclin Y (CCNY) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cyclin Y (CCNY) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cyclin Y (CCNY) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cyclin Y (CCNY) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cyclin Y (CCNY) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cyclin Y (CCNY) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cyclin Y (CCNY) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cyclin Y (CCNY) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cyclin Y (CCNY) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cyclin Y (CCNY) Bioactivity
Antibodies NONE Monoclonal Antibody to Cyclin Y (CCNY) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cyclin Y (CCNY) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cyclin Y (CCNY) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cyclin Y (CCNY) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cyclin Y (CCNY) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cyclin Y (CCNY) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cyclin Y (CCNY) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cyclin Y (CCNY) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cyclin Y (CCNY) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cyclin Y (CCNY) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cyclin Y (CCNY) Bioactivity
Antibodies NONE Monoclonal Antibody to Cyclin Y (CCNY) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cyclin Y (CCNY) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cyclin Y (CCNY) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cyclin Y (CCNY) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cyclin Y (CCNY) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cyclin Y (CCNY) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cyclin Y (CCNY) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cyclin Y (CCNY) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cyclin Y (CCNY) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cyclin Y (CCNY) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cyclin Y (CCNY) Bioactivity
Antibodies NONE Monoclonal Antibody to Cyclin Y (CCNY) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cyclin Y (CCNY) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cyclin Y (CCNY) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cyclin Y (CCNY) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cyclin Y (CCNY) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cyclin Y (CCNY) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cyclin Y (CCNY) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cyclin Y (CCNY) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cyclin Y (CCNY) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cyclin Y (CCNY) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cyclin Y (CCNY) Bioactivity
Antibodies NONE Monoclonal Antibody to Cyclin Y (CCNY) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cyclin Y (CCNY) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cyclin Y (CCNY) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cyclin Y (CCNY) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cyclin Y (CCNY) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cyclin Y (CCNY) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cyclin Y (CCNY) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cyclin Y (CCNY) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cyclin Y (CCNY) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cyclin Y (CCNY) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cyclin Y (CCNY) Bioactivity
Antibodies NONE Monoclonal Antibody to Cyclin Y (CCNY) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cyclin Y (CCNY) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cyclin Y (CCNY) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cyclin Y (CCNY) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cyclin Y (CCNY) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cyclin Y (CCNY) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cyclin Y (CCNY) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cyclin Y (CCNY) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cyclin Y (CCNY) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cyclin Y (CCNY) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cyclin Y (CCNY) Bioactivity
Antibodies NONE Monoclonal Antibody to Cyclin Y (CCNY) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cyclin Y (CCNY) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cyclin Y (CCNY) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cyclin Y (CCNY) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cyclin Y (CCNY) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cyclin Y (CCNY) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cyclin Y (CCNY) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cyclin Y (CCNY) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cyclin Y (CCNY) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cyclin Y (CCNY) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cyclin Y (CCNY) Bioactivity
Antibodies NONE Monoclonal Antibody to Cyclin Y (CCNY) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cyclin Y (CCNY) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cyclin Y (CCNY) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cyclin Y (CCNY) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cyclin Y (CCNY) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cyclin Y (CCNY) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cyclin Y (CCNY) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cyclin Y (CCNY) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cyclin Y (CCNY) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cyclin Y (CCNY) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cyclin Y (CCNY) Bioactivity
Antibodies NONE Monoclonal Antibody to Cyclin Y (CCNY) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cyclin Y (CCNY) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cyclin Y (CCNY) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cyclin Y (CCNY) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cyclin Y (CCNY) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cyclin Y (CCNY) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cyclin Y (CCNY) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cyclin Y (CCNY) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cyclin Y (CCNY) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Cyclin Y (CCNY) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Cyclin Y (CCNY) Bioactivity
Antibodies NONE Monoclonal Antibody to Cyclin Y (CCNY) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Cyclin Y (CCNY) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Cyclin Y (CCNY) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Cyclin Y (CCNY) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Cyclin Y (CCNY) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Cyclin Y (CCNY) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Cyclin Y (CCNY) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Cyclin Y (CCNY) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Cyclin Y (CCNY) CLIA assay for Antigen Detection

Reference

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FEBS Lett. 583:2171-2178(2009) [PubMed] [Europe PMC] [Abstract]

"Identification and characterization of cyclin X which activates transcriptional activities of c-Myc."
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"The full-ORF clone resource of the German cDNA consortium."
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"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
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"Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]

"Phosphorylation analysis of primary human T lymphocytes using sequential IMAC and titanium oxide enrichment."
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"Phosphoproteome of resting human platelets."
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"A quantitative atlas of mitotic phosphorylation."
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"Cell cycle control of wnt receptor activation."
Dev. Cell 17:788-799(2009) [PubMed] [Europe PMC] [Abstract]

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"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
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"System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]

"Cyclin-dependent kinase 16/PCTAIRE kinase 1 is activated by cyclin Y and is essential for spermatogenesis."
Mol. Cell. Biol. 32:868-879(2012) [PubMed] [Europe PMC] [Abstract]

"Phosphorylation of cyclin Y by CDK14 induces its ubiquitination and degradation."
FEBS Lett. 588:1989-1996(2014) [PubMed] [Europe PMC] [Abstract]

"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]