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Hexokinase 2 (HK2)
Hexokinase 2 (HK2)
HK II; Muscle form hexokinase
Hexokinase II is the major hexokinase expressed in skeletal muscle. Insulin has been shown to increase transcription of this gene. Lehto et al. (1993) described the isolation of genomic clones for human hexokinase-2. These clones were isolated by screening a human placental genomic library with a rat hexokinase-2 cDNA clone. A genomic clone derived from this screening was used in fluorescence in situ hybridization studies and was found to map to human chromosome 2p13.1. The human HK2 genomic clones were also screened for dinucleotide repeats. Primers were selected to amplify an approximately 224-bp CA-repeat-rich region. This repeat region was highly polymorphic; the level of heterozygosity was 0.63 in Caucasians and 0.51 in Chinese subjects.
Organism species: Homo sapiens (Human)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
T429Hu01
Recombinant Hexokinase 2 (HK2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Hexokinase 2 (HK2) Bioactivity
Antibodies
MT429Hu21
Monoclonal Antibody to Hexokinase 2 (HK2) WB; IHC; ICC; IP.
PT429Hu01
Polyclonal Antibody to Hexokinase 2 (HK2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Hexokinase 2 (HK2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Hexokinase 2 (HK2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Hexokinase 2 (HK2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Hexokinase 2 (HK2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Hexokinase 2 (HK2) Flow Cytometry;ICC/IF
Assay Kits
KET429Hu
ELISA Kit for Hexokinase 2 (HK2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Hexokinase 2 (HK2) CLIA assay for Antigen Detection
Organism species: Mus musculus (Mouse)
Organism species: Rattus norvegicus (Rat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Hexokinase 2 (HK2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Hexokinase 2 (HK2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Hexokinase 2 (HK2) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Hexokinase 2 (HK2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Hexokinase 2 (HK2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Hexokinase 2 (HK2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Hexokinase 2 (HK2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Hexokinase 2 (HK2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Hexokinase 2 (HK2) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Hexokinase 2 (HK2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Hexokinase 2 (HK2) CLIA assay for Antigen Detection
Organism species: Canis familiaris; Canine (Dog)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Hexokinase 2 (HK2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Hexokinase 2 (HK2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Hexokinase 2 (HK2) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Hexokinase 2 (HK2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Hexokinase 2 (HK2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Hexokinase 2 (HK2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Hexokinase 2 (HK2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Hexokinase 2 (HK2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Hexokinase 2 (HK2) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Hexokinase 2 (HK2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Hexokinase 2 (HK2) CLIA assay for Antigen Detection
Organism species: Sus scrofa; Porcine (Pig)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Hexokinase 2 (HK2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Hexokinase 2 (HK2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Hexokinase 2 (HK2) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Hexokinase 2 (HK2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Hexokinase 2 (HK2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Hexokinase 2 (HK2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Hexokinase 2 (HK2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Hexokinase 2 (HK2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Hexokinase 2 (HK2) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Hexokinase 2 (HK2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Hexokinase 2 (HK2) CLIA assay for Antigen Detection
Organism species: Bos taurus; Bovine (Cattle)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Hexokinase 2 (HK2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Hexokinase 2 (HK2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Hexokinase 2 (HK2) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Hexokinase 2 (HK2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Hexokinase 2 (HK2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Hexokinase 2 (HK2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Hexokinase 2 (HK2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Hexokinase 2 (HK2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Hexokinase 2 (HK2) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Hexokinase 2 (HK2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Hexokinase 2 (HK2) CLIA assay for Antigen Detection
Organism species: Rhesus monkey (Simian)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Hexokinase 2 (HK2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Hexokinase 2 (HK2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Hexokinase 2 (HK2) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Hexokinase 2 (HK2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Hexokinase 2 (HK2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Hexokinase 2 (HK2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Hexokinase 2 (HK2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Hexokinase 2 (HK2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Hexokinase 2 (HK2) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Hexokinase 2 (HK2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Hexokinase 2 (HK2) CLIA assay for Antigen Detection
Organism species: Chicken (Gallus)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Hexokinase 2 (HK2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Hexokinase 2 (HK2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Hexokinase 2 (HK2) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Hexokinase 2 (HK2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Hexokinase 2 (HK2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Hexokinase 2 (HK2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Hexokinase 2 (HK2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Hexokinase 2 (HK2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Hexokinase 2 (HK2) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Hexokinase 2 (HK2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Hexokinase 2 (HK2) CLIA assay for Antigen Detection
Organism species: Ovis aries; Ovine (Sheep)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Hexokinase 2 (HK2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Hexokinase 2 (HK2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Hexokinase 2 (HK2) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Hexokinase 2 (HK2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Hexokinase 2 (HK2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Hexokinase 2 (HK2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Hexokinase 2 (HK2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Hexokinase 2 (HK2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Hexokinase 2 (HK2) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Hexokinase 2 (HK2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Hexokinase 2 (HK2) CLIA assay for Antigen Detection
Organism species: Oryctolagus cuniculus (Rabbit)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Hexokinase 2 (HK2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Hexokinase 2 (HK2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Hexokinase 2 (HK2) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Hexokinase 2 (HK2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Hexokinase 2 (HK2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Hexokinase 2 (HK2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Hexokinase 2 (HK2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Hexokinase 2 (HK2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Hexokinase 2 (HK2) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Hexokinase 2 (HK2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Hexokinase 2 (HK2) CLIA assay for Antigen Detection
Organism species: Cavia (Guinea pig )
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Hexokinase 2 (HK2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Hexokinase 2 (HK2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Hexokinase 2 (HK2) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Hexokinase 2 (HK2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Hexokinase 2 (HK2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Hexokinase 2 (HK2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Hexokinase 2 (HK2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Hexokinase 2 (HK2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Hexokinase 2 (HK2) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Hexokinase 2 (HK2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Hexokinase 2 (HK2) CLIA assay for Antigen Detection
Organism species: Equus caballus; Equine (Horse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Hexokinase 2 (HK2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Hexokinase 2 (HK2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Hexokinase 2 (HK2) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Hexokinase 2 (HK2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Hexokinase 2 (HK2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Hexokinase 2 (HK2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Hexokinase 2 (HK2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Hexokinase 2 (HK2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Hexokinase 2 (HK2) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Hexokinase 2 (HK2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Hexokinase 2 (HK2) CLIA assay for Antigen Detection
Organism species: Capra hircus; Caprine (Goat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Hexokinase 2 (HK2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Hexokinase 2 (HK2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Hexokinase 2 (HK2) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Hexokinase 2 (HK2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Hexokinase 2 (HK2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Hexokinase 2 (HK2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Hexokinase 2 (HK2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Hexokinase 2 (HK2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Hexokinase 2 (HK2) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Hexokinase 2 (HK2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Hexokinase 2 (HK2) CLIA assay for Antigen Detection
Organism species: Pan-species (General)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Hexokinase 2 (HK2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Hexokinase 2 (HK2) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Hexokinase 2 (HK2) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Hexokinase 2 (HK2) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Hexokinase 2 (HK2) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Hexokinase 2 (HK2) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Hexokinase 2 (HK2) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Hexokinase 2 (HK2) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Hexokinase 2 (HK2) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Hexokinase 2 (HK2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Hexokinase 2 (HK2) CLIA assay for Antigen Detection
Reference
"Human hexokinase II: sequence and homology to other hexokinases." Biochem. Biophys. Res. Commun. 197:68-74(1993) [PubMed ] [Europe PMC ] [Abstract ]
"Human hexokinase II gene: exon-intron organization, mutation screening in NIDDM, and its relationship to muscle hexokinase activity." Diabetologia 38:1466-1474(1995) [PubMed ] [Europe PMC ] [Abstract ]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." Genome Res. 14:2121-2127(2004) [PubMed ] [Europe PMC ] [Abstract ]
"Steady state transcript levels of the type II hexokinase and type 1 glucose transporter in human tumor cell lines." Cancer Lett. 82:27-32(1994) [PubMed ] [Europe PMC ] [Abstract ]
"Initial characterization of the human central proteome." BMC Syst. Biol. 5:17-17(2011) [PubMed ] [Europe PMC ] [Abstract ]
"Crystal structure of human hexokinase II."
"Amino acid substitutions in hexokinase II among patients with NIDDM." Diabetes 44:330-334(1995) [PubMed ] [Europe PMC ] [Abstract ]
"Analysis of the hexokinase II gene in subjects with insulin resistance and NIDDM and detection of a Gln142-->His substitution." Diabetes 44:340-346(1995) [PubMed ] [Europe PMC ] [Abstract ]
"Identification of four amino acid substitutions in hexokinase II and studies of relationships to NIDDM, glucose effectiveness, and insulin sensitivity." Diabetes 44:347-353(1995) [PubMed ] [Europe PMC ] [Abstract ]
