Myosin IE (MYO1E)
MYO1C; HuncM-IC; Myosin-Ic
Bement et al. (1994) cloned a human unconventional myosin gene, MYO1E, encoding a predicted 127-kD polypeptide of 1,109 amino acids. The gene, which they designated myosin IC, contains a characteristic N-terminal myosin head, a single 'IQ motif' predicted to bind a single myosin light chain, and a C-terminal tail with a putative membrane-binding site. They also noted the presence of a C-terminal src-homology domain, reminiscent of 'long-tailed' myosins I from amoeboid organisms. By Northern analysis, Bement et al. (1994) detected ubiquitous expression of MYO1E.MYO1E (formerly MYO1C), MYO1A, MYO1F , and MYO10. The MYO1E gene was found to be located on 15q21-q22 in the precise location predicted from its location on chromosome 9 of the mouse.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Myosin IE (MYO1E) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Myosin IE (MYO1E) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Myosin IE (MYO1E) | WB; IHC; ICC; IP. |
| PT348Hu01 | Polyclonal Antibody to Myosin IE (MYO1E) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Myosin IE (MYO1E) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Myosin IE (MYO1E) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Myosin IE (MYO1E) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Myosin IE (MYO1E) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Myosin IE (MYO1E) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Myosin IE (MYO1E) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Myosin IE (MYO1E) | CLIA assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Myosin IE (MYO1E) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Myosin IE (MYO1E) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Myosin IE (MYO1E) | WB; IHC; ICC; IP. |
| PT348Mu01 | Polyclonal Antibody to Myosin IE (MYO1E) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Myosin IE (MYO1E) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Myosin IE (MYO1E) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Myosin IE (MYO1E) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Myosin IE (MYO1E) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Myosin IE (MYO1E) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Myosin IE (MYO1E) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Myosin IE (MYO1E) | CLIA assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Myosin IE (MYO1E) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Myosin IE (MYO1E) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Myosin IE (MYO1E) | WB; IHC; ICC; IP. |
| PT348Ra01 | Polyclonal Antibody to Myosin IE (MYO1E) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Myosin IE (MYO1E) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Myosin IE (MYO1E) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Myosin IE (MYO1E) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Myosin IE (MYO1E) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Myosin IE (MYO1E) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Myosin IE (MYO1E) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Myosin IE (MYO1E) | CLIA assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Myosin IE (MYO1E) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Myosin IE (MYO1E) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Myosin IE (MYO1E) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Myosin IE (MYO1E) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Myosin IE (MYO1E) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Myosin IE (MYO1E) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Myosin IE (MYO1E) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Myosin IE (MYO1E) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Myosin IE (MYO1E) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Myosin IE (MYO1E) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Myosin IE (MYO1E) | CLIA assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Myosin IE (MYO1E) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Myosin IE (MYO1E) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Myosin IE (MYO1E) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Myosin IE (MYO1E) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Myosin IE (MYO1E) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Myosin IE (MYO1E) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Myosin IE (MYO1E) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Myosin IE (MYO1E) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Myosin IE (MYO1E) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Myosin IE (MYO1E) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Myosin IE (MYO1E) | CLIA assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Myosin IE (MYO1E) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Myosin IE (MYO1E) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Myosin IE (MYO1E) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Myosin IE (MYO1E) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Myosin IE (MYO1E) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Myosin IE (MYO1E) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Myosin IE (MYO1E) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Myosin IE (MYO1E) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Myosin IE (MYO1E) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Myosin IE (MYO1E) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Myosin IE (MYO1E) | CLIA assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Myosin IE (MYO1E) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Myosin IE (MYO1E) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Myosin IE (MYO1E) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Myosin IE (MYO1E) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Myosin IE (MYO1E) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Myosin IE (MYO1E) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Myosin IE (MYO1E) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Myosin IE (MYO1E) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Myosin IE (MYO1E) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Myosin IE (MYO1E) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Myosin IE (MYO1E) | CLIA assay for Antigen Detection |
Organism species: Chicken (Gallus)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Myosin IE (MYO1E) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Myosin IE (MYO1E) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Myosin IE (MYO1E) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Myosin IE (MYO1E) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Myosin IE (MYO1E) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Myosin IE (MYO1E) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Myosin IE (MYO1E) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Myosin IE (MYO1E) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Myosin IE (MYO1E) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Myosin IE (MYO1E) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Myosin IE (MYO1E) | CLIA assay for Antigen Detection |
Organism species: Ovis aries; Ovine (Sheep)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Myosin IE (MYO1E) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Myosin IE (MYO1E) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Myosin IE (MYO1E) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Myosin IE (MYO1E) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Myosin IE (MYO1E) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Myosin IE (MYO1E) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Myosin IE (MYO1E) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Myosin IE (MYO1E) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Myosin IE (MYO1E) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Myosin IE (MYO1E) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Myosin IE (MYO1E) | CLIA assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Myosin IE (MYO1E) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Myosin IE (MYO1E) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Myosin IE (MYO1E) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Myosin IE (MYO1E) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Myosin IE (MYO1E) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Myosin IE (MYO1E) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Myosin IE (MYO1E) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Myosin IE (MYO1E) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Myosin IE (MYO1E) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Myosin IE (MYO1E) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Myosin IE (MYO1E) | CLIA assay for Antigen Detection |
Organism species: Cavia (Guinea pig )
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Myosin IE (MYO1E) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Myosin IE (MYO1E) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Myosin IE (MYO1E) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Myosin IE (MYO1E) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Myosin IE (MYO1E) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Myosin IE (MYO1E) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Myosin IE (MYO1E) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Myosin IE (MYO1E) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Myosin IE (MYO1E) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Myosin IE (MYO1E) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Myosin IE (MYO1E) | CLIA assay for Antigen Detection |
Organism species: Equus caballus; Equine (Horse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Myosin IE (MYO1E) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Myosin IE (MYO1E) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Myosin IE (MYO1E) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Myosin IE (MYO1E) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Myosin IE (MYO1E) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Myosin IE (MYO1E) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Myosin IE (MYO1E) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Myosin IE (MYO1E) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Myosin IE (MYO1E) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Myosin IE (MYO1E) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Myosin IE (MYO1E) | CLIA assay for Antigen Detection |
Organism species: Capra hircus; Caprine (Goat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Myosin IE (MYO1E) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Myosin IE (MYO1E) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Myosin IE (MYO1E) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Myosin IE (MYO1E) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Myosin IE (MYO1E) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Myosin IE (MYO1E) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Myosin IE (MYO1E) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Myosin IE (MYO1E) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Myosin IE (MYO1E) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Myosin IE (MYO1E) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Myosin IE (MYO1E) | CLIA assay for Antigen Detection |
Organism species: Pan-species (General)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Myosin IE (MYO1E) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Myosin IE (MYO1E) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Myosin IE (MYO1E) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Myosin IE (MYO1E) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Myosin IE (MYO1E) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Myosin IE (MYO1E) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Myosin IE (MYO1E) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Myosin IE (MYO1E) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Myosin IE (MYO1E) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Myosin IE (MYO1E) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Myosin IE (MYO1E) | CLIA assay for Antigen Detection |
Reference
"Cloning and mRNA expression of human unconventional myosin-IC. A homologue of amoeboid myosins-I with a single IQ motif and an SH3 domain."
J. Mol. Biol. 243:356-363(1994) [PubMed] [Europe PMC] [Abstract]
"Analysis of the DNA sequence and duplication history of human chromosome 15."
Nature 440:671-675(2006) [PubMed] [Europe PMC] [Abstract]
"Identification and overlapping expression of multiple unconventional myosin genes in vertebrate cell types."
Proc. Natl. Acad. Sci. U.S.A. 91:6549-6553(1994) [PubMed] [Europe PMC] [Abstract]
Erratum
Proc. Natl. Acad. Sci. U.S.A. 91:11767-11767(1994) [PubMed] [Europe PMC] [Abstract]
"The kinetic mechanism of Myo1e (human myosin-IC)."
J. Biol. Chem. 277:21514-21521(2002) [PubMed] [Europe PMC] [Abstract]
"Myosin 1E interacts with synaptojanin-1 and dynamin and is involved in endocytosis."
FEBS Lett. 581:644-650(2007) [PubMed] [Europe PMC] [Abstract]
"A quantitative atlas of mitotic phosphorylation."
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
"Myo1e binds anionic phospholipids with high affinity."
Biochemistry 49:9353-9360(2010) [PubMed] [Europe PMC] [Abstract]
"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
"Initial characterization of the human central proteome."
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
"A Genome-wide multidimensional RNAi screen reveals pathways controlling MHC class II antigen presentation."
Cell 145:268-283(2011) [PubMed] [Europe PMC] [Abstract]
"MYO1E mutations and childhood familial focal segmental glomerulosclerosis."
N. Engl. J. Med. 365:295-306(2011) [PubMed] [Europe PMC] [Abstract]
"Exome sequencing identified MYO1E and NEIL1 as candidate genes for human autosomal recessive steroid-resistant nephrotic syndrome."
Kidney Int. 80:389-396(2011) [PubMed] [Europe PMC] [Abstract]