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Surfactant Associated Protein A2 (SPA2)

SFTPA2B; COLEC5; SP2A; SPA1 beta; SP-A2; SPAII; Collectin-5; Pulmonary Surfactant Protein A2; 35 kDa pulmonary surfactant-associated protein; Alveolar proteinosis protein

Pulmonary Surfactant Associated Protein A2 is one of several genes encoding pulmonary-surfactant associated proteins (SFTPA) located on chromosome 10. Mutations in this gene and a highly similar gene located nearby, which affect the highly conserved carbohydrate recognition domain, are associated with idiopathic pulmonary fibrosis. The current version of the assembly displays only a single centromeric SFTPA gene pair rather than the two gene pairs shown in the previous assembly which were thought to have resulted from a duplication.SPA2 transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPT262Hu01 Recombinant Surfactant Associated Protein A2 (SPA2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAT262Hu01 Monoclonal Antibody to Surfactant Associated Protein A2 (SPA2) WB; IHC; ICC; IP.
PAT262Hu01 Polyclonal Antibody to Surfactant Associated Protein A2 (SPA2) WB; IHC; ICC; IF.
Assay Kits CLT262Hu01 CLIA Kit for Surfactant Associated Protein A2 (SPA2) CLIA assay for Antigen Detection
ELT262Hu01 ELISA Kit for Surfactant Associated Protein A2 (SPA2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPT262Mu01 Recombinant Surfactant Associated Protein A2 (SPA2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAT262Mu01 Monoclonal Antibody to Surfactant Associated Protein A2 (SPA2) WB; IHC; ICC; IP.
PAT262Mu01 Polyclonal Antibody to Surfactant Associated Protein A2 (SPA2) WB; IHC; ICC; IF.
Assay Kits CLT262Mu01 CLIA Kit for Surfactant Associated Protein A2 (SPA2) CLIA assay for Antigen Detection
ELT262Mu01 ELISA Kit for Surfactant Associated Protein A2 (SPA2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPT262Ra01 Recombinant Surfactant Associated Protein A2 (SPA2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAT262Ra01 Monoclonal Antibody to Surfactant Associated Protein A2 (SPA2) WB; IHC; ICC; IP.
PAT262Ra01 Polyclonal Antibody to Surfactant Associated Protein A2 (SPA2) WB; IHC; ICC; IF.
Assay Kits CLT262Ra01 CLIA Kit for Surfactant Associated Protein A2 (SPA2) CLIA assay for Antigen Detection
ELT262Ra01 ELISA Kit for Surfactant Associated Protein A2 (SPA2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPT262Ca01 Recombinant Surfactant Associated Protein A2 (SPA2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAT262Ca01 Monoclonal Antibody to Surfactant Associated Protein A2 (SPA2) WB; IHC; ICC; IP.
PAT262Ca01 Polyclonal Antibody to Surfactant Associated Protein A2 (SPA2) WB; IHC; ICC; IF.
Assay Kits CLT262Ca01 CLIA Kit for Surfactant Associated Protein A2 (SPA2) CLIA assay for Antigen Detection
ELT262Ca01 ELISA Kit for Surfactant Associated Protein A2 (SPA2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPT262Po01 Recombinant Surfactant Associated Protein A2 (SPA2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAT262Po01 Monoclonal Antibody to Surfactant Associated Protein A2 (SPA2) WB; IHC; ICC; IP.
PAT262Po01 Polyclonal Antibody to Surfactant Associated Protein A2 (SPA2) WB; IHC; ICC; IF.
Assay Kits CLT262Po01 CLIA Kit for Surfactant Associated Protein A2 (SPA2) CLIA assay for Antigen Detection
ELT262Po01 ELISA Kit for Surfactant Associated Protein A2 (SPA2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPT262Bo01 Recombinant Surfactant Associated Protein A2 (SPA2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAT262Bo01 Monoclonal Antibody to Surfactant Associated Protein A2 (SPA2) WB; IHC; ICC; IP.
PAT262Bo01 Polyclonal Antibody to Surfactant Associated Protein A2 (SPA2) WB; IHC; ICC; IF.
Assay Kits CLT262Bo01 CLIA Kit for Surfactant Associated Protein A2 (SPA2) CLIA assay for Antigen Detection
ELT262Bo01 ELISA Kit for Surfactant Associated Protein A2 (SPA2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPT262Rb01 Recombinant Surfactant Associated Protein A2 (SPA2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAT262Rb01 Monoclonal Antibody to Surfactant Associated Protein A2 (SPA2) WB; IHC; ICC; IP.
PAT262Rb01 Polyclonal Antibody to Surfactant Associated Protein A2 (SPA2) WB; IHC; ICC; IF.
Assay Kits CLT262Rb01 CLIA Kit for Surfactant Associated Protein A2 (SPA2) CLIA assay for Antigen Detection
ELT262Rb01 ELISA Kit for Surfactant Associated Protein A2 (SPA2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPT262Mo01 Recombinant Surfactant Associated Protein A2 (SPA2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAT262Mo01 Monoclonal Antibody to Surfactant Associated Protein A2 (SPA2) WB; IHC; ICC; IP.
PAT262Mo01 Polyclonal Antibody to Surfactant Associated Protein A2 (SPA2) WB; IHC; ICC; IF.
Assay Kits CLT262Mo01 CLIA Kit for Surfactant Associated Protein A2 (SPA2) CLIA assay for Antigen Detection
ELT262Mo01 ELISA Kit for Surfactant Associated Protein A2 (SPA2) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"Isolation and characterization of cDNA clones for the 35-kDa pulmonary surfactant-associated protein."
J. Biol. Chem. 261:9029-9033(1986) [PubMed] [Europe PMC] [Abstract]

"Characterization of a second human pulmonary surfactant-associated protein SP-A gene."
Am. J. Respir. Cell Mol. Biol. 6:446-452(1992) [PubMed] [Europe PMC] [Abstract]

"Human SP-A1 (SFTPA1) variant-specific 3' UTRs and poly(A) tail differentially affect the in vitro translation of a reporter gene."
Am. J. Physiol. 299:L523-L534(2010) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence and comparative analysis of human chromosome 10."
Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Studies of the structure of lung surfactant protein SP-A."
Am. J. Physiol. 257:L421-L429(1989) [PubMed] [Europe PMC] [Abstract]

"Genetics of the hydrophilic surfactant proteins A and D."
Biochim. Biophys. Acta 1408:312-322(1998) [PubMed] [Europe PMC] [Abstract]

"Genetic defects in surfactant protein A2 are associated with pulmonary fibrosis and lung cancer."
Am. J. Hum. Genet. 84:52-59(2009) [PubMed] [Europe PMC] [Abstract]