Regulator Of G Protein Signaling 6 (RGS6)
GAP; S914
Members of the RGS (regulator of G protein signaling) family have been shown to modulate the functioning of G proteins by activating the intrinsic GTPase activity of the alpha (guanine nucleotide-binding) subunits.
RGS6, The predicted 472-amino acid protein has a calculated molecular mass of 54.4 kD. It contains an N-terminal dishevelled /egl10/pleckstrin (DEP) domain, a central G protein gamma subunit (GNG2)-like (GGL) domain, and an RGS domain near the C terminus. The variants encode proteins with long or short N-terminal domains, complete or incomplete GGL domains, 7 distinct C-terminal domains, and a common internal domain that includes the RGS domain.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT078Hu01 | Recombinant Regulator Of G Protein Signaling 6 (RGS6) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT078Hu01 | Monoclonal Antibody to Regulator Of G Protein Signaling 6 (RGS6) | WB; IHC; ICC; IP. |
| PAT078Hu01 | Polyclonal Antibody to Regulator Of G Protein Signaling 6 (RGS6) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT078Hu01 | CLIA Kit for Regulator Of G Protein Signaling 6 (RGS6) | CLIA assay for Antigen Detection |
| ELT078Hu01 | ELISA Kit for Regulator Of G Protein Signaling 6 (RGS6) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT078Mu01 | Recombinant Regulator Of G Protein Signaling 6 (RGS6) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT078Mu01 | Monoclonal Antibody to Regulator Of G Protein Signaling 6 (RGS6) | WB; IHC; ICC; IP. |
| PAT078Mu01 | Polyclonal Antibody to Regulator Of G Protein Signaling 6 (RGS6) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT078Mu01 | CLIA Kit for Regulator Of G Protein Signaling 6 (RGS6) | CLIA assay for Antigen Detection |
| ELT078Mu01 | ELISA Kit for Regulator Of G Protein Signaling 6 (RGS6) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT078Ra01 | Recombinant Regulator Of G Protein Signaling 6 (RGS6) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT078Ra01 | Monoclonal Antibody to Regulator Of G Protein Signaling 6 (RGS6) | WB; IHC; ICC; IP. |
| PAT078Ra01 | Polyclonal Antibody to Regulator Of G Protein Signaling 6 (RGS6) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT078Ra01 | CLIA Kit for Regulator Of G Protein Signaling 6 (RGS6) | CLIA assay for Antigen Detection |
| ELT078Ra01 | ELISA Kit for Regulator Of G Protein Signaling 6 (RGS6) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT078Ca01 | Recombinant Regulator Of G Protein Signaling 6 (RGS6) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT078Ca01 | Monoclonal Antibody to Regulator Of G Protein Signaling 6 (RGS6) | WB; IHC; ICC; IP. |
| PAT078Ca01 | Polyclonal Antibody to Regulator Of G Protein Signaling 6 (RGS6) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT078Ca01 | CLIA Kit for Regulator Of G Protein Signaling 6 (RGS6) | CLIA assay for Antigen Detection |
| ELT078Ca01 | ELISA Kit for Regulator Of G Protein Signaling 6 (RGS6) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT078Po01 | Recombinant Regulator Of G Protein Signaling 6 (RGS6) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT078Po01 | Monoclonal Antibody to Regulator Of G Protein Signaling 6 (RGS6) | WB; IHC; ICC; IP. |
| PAT078Po01 | Polyclonal Antibody to Regulator Of G Protein Signaling 6 (RGS6) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT078Po01 | CLIA Kit for Regulator Of G Protein Signaling 6 (RGS6) | CLIA assay for Antigen Detection |
| ELT078Po01 | ELISA Kit for Regulator Of G Protein Signaling 6 (RGS6) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT078Bo01 | Recombinant Regulator Of G Protein Signaling 6 (RGS6) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT078Bo01 | Monoclonal Antibody to Regulator Of G Protein Signaling 6 (RGS6) | WB; IHC; ICC; IP. |
| PAT078Bo01 | Polyclonal Antibody to Regulator Of G Protein Signaling 6 (RGS6) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT078Bo01 | CLIA Kit for Regulator Of G Protein Signaling 6 (RGS6) | CLIA assay for Antigen Detection |
| ELT078Bo01 | ELISA Kit for Regulator Of G Protein Signaling 6 (RGS6) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT078Rb01 | Recombinant Regulator Of G Protein Signaling 6 (RGS6) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT078Rb01 | Monoclonal Antibody to Regulator Of G Protein Signaling 6 (RGS6) | WB; IHC; ICC; IP. |
| PAT078Rb01 | Polyclonal Antibody to Regulator Of G Protein Signaling 6 (RGS6) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT078Rb01 | CLIA Kit for Regulator Of G Protein Signaling 6 (RGS6) | CLIA assay for Antigen Detection |
| ELT078Rb01 | ELISA Kit for Regulator Of G Protein Signaling 6 (RGS6) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPT078Mo01 | Recombinant Regulator Of G Protein Signaling 6 (RGS6) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAT078Mo01 | Monoclonal Antibody to Regulator Of G Protein Signaling 6 (RGS6) | WB; IHC; ICC; IP. |
| PAT078Mo01 | Polyclonal Antibody to Regulator Of G Protein Signaling 6 (RGS6) | WB; IHC; ICC; IF. | |
| Assay Kits | CLT078Mo01 | CLIA Kit for Regulator Of G Protein Signaling 6 (RGS6) | CLIA assay for Antigen Detection |
| ELT078Mo01 | ELISA Kit for Regulator Of G Protein Signaling 6 (RGS6) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Human RGS6 gene structure, complex alternative splicing, and role of N terminus and G protein gamma-subunit-like (GGL) domain in subcellular localization of RGS6 splice variants."
J. Biol. Chem. 278:30261-30271(2003) [PubMed] [Europe PMC] [Abstract]
"Fidelity of G protein beta-subunit association by the G protein gamma-subunit-like domains of RGS6, RGS7, and RGS11."
Proc. Natl. Acad. Sci. U.S.A. 96:6489-6494(1999) [PubMed] [Europe PMC] [Abstract]
"Regulators of G protein signaling 6 and 7. Purification of complexes with gbeta5 and assessment of their effects on g protein-mediated signaling pathways."
J. Biol. Chem. 274:31087-31093(1999) [PubMed] [Europe PMC] [Abstract]
"The DNA sequence and analysis of human chromosome 14."
Nature 421:601-607(2003) [PubMed] [Europe PMC] [Abstract]
"Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease."
Nature 375:754-760(1995) [PubMed] [Europe PMC] [Abstract]
"Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits."
Proc. Natl. Acad. Sci. U.S.A. 105:6457-6462(2008) [PubMed] [Europe PMC] [Abstract]