Apolipoprotein L (APOL1)
Apo-L; APOL; APOL-I
Apolipoprotein L (APOL) proteins belong to the high density lipoprotein family, which plays a central role in cholesterol transport. The cholesterol content of membranes is important in cellular processes such as modulating gene transcription and signal transduction both in the adult brain and during neurodevelopment. The 6 APOL genes are clustered on chromosome 22q12.3.
The cDNA encodes a 383-amino acid polypeptide that includes a 12-amino acid secretory signal peptide. Northern blot analysis detected a 1.3-kb APOL transcript in the pancreas but not in any other human tissues. Affinity immunosorption showed that APOL is not free in the plasma, but is associated with lipoproteins containing APOA1. APOL was found in high density lipoprotein fractions.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | T043Hu01 | Recombinant Apolipoprotein L (APOL1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Apolipoprotein L (APOL1) | Bioactivity | |
| Antibodies | MT043Hu21 | Monoclonal Antibody to Apolipoprotein L (APOL1) | WB; IHC; ICC; IP. |
| PT043Hu01 | Polyclonal Antibody to Apolipoprotein L (APOL1) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | Flow Cytometry;ICC/IF | |
| Assay Kits | KET043Hu | ELISA Kit for Apolipoprotein L (APOL1) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Apolipoprotein L (APOL1) | CLIA assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Apolipoprotein L (APOL1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Apolipoprotein L (APOL1) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Apolipoprotein L (APOL1) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Apolipoprotein L (APOL1) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Apolipoprotein L (APOL1) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Apolipoprotein L (APOL1) | CLIA assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Apolipoprotein L (APOL1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Apolipoprotein L (APOL1) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Apolipoprotein L (APOL1) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Apolipoprotein L (APOL1) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Apolipoprotein L (APOL1) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Apolipoprotein L (APOL1) | CLIA assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Apolipoprotein L (APOL1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Apolipoprotein L (APOL1) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Apolipoprotein L (APOL1) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Apolipoprotein L (APOL1) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Apolipoprotein L (APOL1) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Apolipoprotein L (APOL1) | CLIA assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Apolipoprotein L (APOL1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Apolipoprotein L (APOL1) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Apolipoprotein L (APOL1) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Apolipoprotein L (APOL1) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Apolipoprotein L (APOL1) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Apolipoprotein L (APOL1) | CLIA assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Apolipoprotein L (APOL1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Apolipoprotein L (APOL1) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Apolipoprotein L (APOL1) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Apolipoprotein L (APOL1) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Apolipoprotein L (APOL1) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Apolipoprotein L (APOL1) | CLIA assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Apolipoprotein L (APOL1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Apolipoprotein L (APOL1) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Apolipoprotein L (APOL1) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Apolipoprotein L (APOL1) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Apolipoprotein L (APOL1) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Apolipoprotein L (APOL1) | CLIA assay for Antigen Detection |
Organism species: Chicken (Gallus)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Apolipoprotein L (APOL1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Apolipoprotein L (APOL1) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Apolipoprotein L (APOL1) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Apolipoprotein L (APOL1) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Apolipoprotein L (APOL1) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Apolipoprotein L (APOL1) | CLIA assay for Antigen Detection |
Organism species: Ovis aries; Ovine (Sheep)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Apolipoprotein L (APOL1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Apolipoprotein L (APOL1) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Apolipoprotein L (APOL1) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Apolipoprotein L (APOL1) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Apolipoprotein L (APOL1) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Apolipoprotein L (APOL1) | CLIA assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Apolipoprotein L (APOL1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Apolipoprotein L (APOL1) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Apolipoprotein L (APOL1) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Apolipoprotein L (APOL1) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Apolipoprotein L (APOL1) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Apolipoprotein L (APOL1) | CLIA assay for Antigen Detection |
Organism species: Cavia (Guinea pig )
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Apolipoprotein L (APOL1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Apolipoprotein L (APOL1) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Apolipoprotein L (APOL1) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Apolipoprotein L (APOL1) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Apolipoprotein L (APOL1) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Apolipoprotein L (APOL1) | CLIA assay for Antigen Detection |
Organism species: Equus caballus; Equine (Horse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Apolipoprotein L (APOL1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Apolipoprotein L (APOL1) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Apolipoprotein L (APOL1) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Apolipoprotein L (APOL1) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Apolipoprotein L (APOL1) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Apolipoprotein L (APOL1) | CLIA assay for Antigen Detection |
Organism species: Capra hircus; Caprine (Goat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Apolipoprotein L (APOL1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Apolipoprotein L (APOL1) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Apolipoprotein L (APOL1) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Apolipoprotein L (APOL1) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Apolipoprotein L (APOL1) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Apolipoprotein L (APOL1) | CLIA assay for Antigen Detection |
Organism species: Pan-species (General)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Apolipoprotein L (APOL1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Apolipoprotein L (APOL1) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Apolipoprotein L (APOL1) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Apolipoprotein L (APOL1) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Apolipoprotein L (APOL1) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Apolipoprotein L (APOL1) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Apolipoprotein L (APOL1) | CLIA assay for Antigen Detection |
Reference
"Apolipoprotein L, a new human high density lipoprotein apolipoprotein expressed by the pancreas. Identification, cloning, characterization, and plasma distribution of apolipoprotein L."
J. Biol. Chem. 272:25576-25582(1997) [PubMed] [Europe PMC] [Abstract]
"Apolipoprotein L gene family: tissue-specific expression, splicing, promoter regions; discovery of a new gene."
J. Lipid Res. 42:620-630(2001) [PubMed] [Europe PMC] [Abstract]
"The human apolipoprotein L gene cluster: identification, classification, and sites of distribution."
Genomics 74:71-78(2001) [PubMed] [Europe PMC] [Abstract]
"The apolipoprotein L gene cluster has emerged recently in evolution and is expressed in human vascular tissue."
Genomics 79:539-546(2002) [PubMed] [Europe PMC] [Abstract]
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
"The DNA sequence of human chromosome 22."
Nature 402:489-495(1999) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."
J. Proteome Res. 4:2070-2080(2005) [PubMed] [Europe PMC] [Abstract]
"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
"The consensus coding sequences of human breast and colorectal cancers."
Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]
"Missense mutations in the APOL1 gene are highly associated with end stage kidney disease risk previously attributed to the MYH9 gene."
Hum. Genet. 128:345-350(2010) [PubMed] [Europe PMC] [Abstract]
"Association of trypanolytic ApoL1 variants with kidney disease in African Americans."
Science 329:841-845(2010) [PubMed] [Europe PMC] [Abstract]