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Antitrypsin Related Protein (ATR)
Antitrypsin Related Protein (ATR)
SERPINA2; ARGS; PIL; Putative alpha-1-antitrypsin-related; Protease inhibitor 1-like; Serine(Cysteine)Proteinase Inhibitor,Clade A(Alpha-1 Antiproteinase,Antitrypsin)Member 2
The nucleotide sequence of the ATR gene showed extensive homology with the authentic AAT gene in the introns as well as exons. The conservation of all RNA splice sites and lack of internal termination codons in the exons suggested that it may not be a classic pseudogene. If expressed, it would result in a protein of 420 amino acid residues, exhibiting a 70% overall homology with AAT. The signal peptide sequence was well conserved, but the active site of protease inhibition (met-ser) in AAT had been changed to trp-ser. The findings suggested that the putative protein is a secretory serine protease inhibitor with an altered substrate specificity. Since even the introns showed 65% nucleotide sequence homology with the authentic AAT gene, ATR appears to have been derived from a recent duplication of the AAT gene.
Organism species: Homo sapiens (Human)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
T034Hu01
Recombinant Antitrypsin Related Protein (ATR) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Antitrypsin Related Protein (ATR) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Antitrypsin Related Protein (ATR) WB; IHC; ICC; IP.
PT034Hu01
Polyclonal Antibody to Antitrypsin Related Protein (ATR) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Antitrypsin Related Protein (ATR) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Antitrypsin Related Protein (ATR) CLIA assay for Antigen Detection
Organism species: Mus musculus (Mouse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Antitrypsin Related Protein (ATR) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Antitrypsin Related Protein (ATR) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Antitrypsin Related Protein (ATR) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Antitrypsin Related Protein (ATR) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Antitrypsin Related Protein (ATR) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Antitrypsin Related Protein (ATR) CLIA assay for Antigen Detection
Organism species: Rattus norvegicus (Rat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Antitrypsin Related Protein (ATR) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Antitrypsin Related Protein (ATR) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Antitrypsin Related Protein (ATR) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Antitrypsin Related Protein (ATR) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Antitrypsin Related Protein (ATR) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Antitrypsin Related Protein (ATR) CLIA assay for Antigen Detection
Organism species: Canis familiaris; Canine (Dog)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Antitrypsin Related Protein (ATR) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Antitrypsin Related Protein (ATR) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Antitrypsin Related Protein (ATR) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Antitrypsin Related Protein (ATR) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Antitrypsin Related Protein (ATR) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Antitrypsin Related Protein (ATR) CLIA assay for Antigen Detection
Organism species: Sus scrofa; Porcine (Pig)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Antitrypsin Related Protein (ATR) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Antitrypsin Related Protein (ATR) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Antitrypsin Related Protein (ATR) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Antitrypsin Related Protein (ATR) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Antitrypsin Related Protein (ATR) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Antitrypsin Related Protein (ATR) CLIA assay for Antigen Detection
Organism species: Bos taurus; Bovine (Cattle)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Antitrypsin Related Protein (ATR) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Antitrypsin Related Protein (ATR) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Antitrypsin Related Protein (ATR) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Antitrypsin Related Protein (ATR) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Antitrypsin Related Protein (ATR) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Antitrypsin Related Protein (ATR) CLIA assay for Antigen Detection
Organism species: Rhesus monkey (Simian)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Antitrypsin Related Protein (ATR) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Antitrypsin Related Protein (ATR) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Antitrypsin Related Protein (ATR) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Antitrypsin Related Protein (ATR) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Antitrypsin Related Protein (ATR) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Antitrypsin Related Protein (ATR) CLIA assay for Antigen Detection
Organism species: Chicken (Gallus)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Antitrypsin Related Protein (ATR) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Antitrypsin Related Protein (ATR) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Antitrypsin Related Protein (ATR) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Antitrypsin Related Protein (ATR) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Antitrypsin Related Protein (ATR) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Antitrypsin Related Protein (ATR) CLIA assay for Antigen Detection
Organism species: Ovis aries; Ovine (Sheep)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Antitrypsin Related Protein (ATR) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Antitrypsin Related Protein (ATR) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Antitrypsin Related Protein (ATR) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Antitrypsin Related Protein (ATR) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Antitrypsin Related Protein (ATR) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Antitrypsin Related Protein (ATR) CLIA assay for Antigen Detection
Organism species: Oryctolagus cuniculus (Rabbit)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Antitrypsin Related Protein (ATR) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Antitrypsin Related Protein (ATR) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Antitrypsin Related Protein (ATR) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Antitrypsin Related Protein (ATR) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Antitrypsin Related Protein (ATR) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Antitrypsin Related Protein (ATR) CLIA assay for Antigen Detection
Organism species: Cavia (Guinea pig )
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Antitrypsin Related Protein (ATR) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Antitrypsin Related Protein (ATR) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Antitrypsin Related Protein (ATR) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Antitrypsin Related Protein (ATR) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Antitrypsin Related Protein (ATR) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Antitrypsin Related Protein (ATR) CLIA assay for Antigen Detection
Organism species: Equus caballus; Equine (Horse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Antitrypsin Related Protein (ATR) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Antitrypsin Related Protein (ATR) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Antitrypsin Related Protein (ATR) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Antitrypsin Related Protein (ATR) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Antitrypsin Related Protein (ATR) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Antitrypsin Related Protein (ATR) CLIA assay for Antigen Detection
Organism species: Capra hircus; Caprine (Goat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Antitrypsin Related Protein (ATR) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Antitrypsin Related Protein (ATR) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Antitrypsin Related Protein (ATR) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Antitrypsin Related Protein (ATR) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Antitrypsin Related Protein (ATR) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Antitrypsin Related Protein (ATR) CLIA assay for Antigen Detection
Organism species: Pan-species (General)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Antitrypsin Related Protein (ATR) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Antitrypsin Related Protein (ATR) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Antitrypsin Related Protein (ATR) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Antitrypsin Related Protein (ATR) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Antitrypsin Related Protein (ATR) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Antitrypsin Related Protein (ATR) CLIA assay for Antigen Detection
Reference
"Molecular structure and sequence homology of a gene related to alpha 1-antitrypsin in the human genome." Genomics 2:165-173(1988) [PubMed ] [Europe PMC ] [Abstract ]
"Molecular linkage of the human alpha 1-antitrypsin and corticosteroid-binding globulin genes on chromosome 14q32.1." Mamm. Genome 8:913-916(1997) [PubMed ] [Europe PMC ] [Abstract ]
"Sequence diversity at the proximal 14q32.1 SERPIN subcluster: evidence for natural selection favoring the pseudogenization of SERPINA2." Mol. Biol. Evol. 24:587-598(2007) [PubMed ] [Europe PMC ] [Abstract ]
"SERPINA2 is a novel gene with a divergent function from SERPINA1." PLoS ONE 8:E66889-E66889(2013) [PubMed ] [Europe PMC ] [Abstract ]