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Antitrypsin Related Protein (ATR)

SERPINA2; ARGS; PIL; Putative alpha-1-antitrypsin-related; Protease inhibitor 1-like; Serine(Cysteine)Proteinase Inhibitor,Clade A(Alpha-1 Antiproteinase,Antitrypsin)Member 2

The nucleotide sequence of the ATR gene showed extensive homology with the authentic AAT gene in the introns as well as exons. The conservation of all RNA splice sites and lack of internal termination codons in the exons suggested that it may not be a classic pseudogene. If expressed, it would result in a protein of 420 amino acid residues, exhibiting a 70% overall homology with AAT. The signal peptide sequence was well conserved, but the active site of protease inhibition (met-ser) in AAT had been changed to trp-ser. The findings suggested that the putative protein is a secretory serine protease inhibitor with an altered substrate specificity. Since even the introns showed 65% nucleotide sequence homology with the authentic AAT gene, ATR appears to have been derived from a recent duplication of the AAT gene.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins T034Hu01 Recombinant Antitrypsin Related Protein (ATR) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Antitrypsin Related Protein (ATR) Bioactivity
Antibodies NONE Monoclonal Antibody to Antitrypsin Related Protein (ATR) WB; IHC; ICC; IP.
PT034Hu01 Polyclonal Antibody to Antitrypsin Related Protein (ATR) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Antitrypsin Related Protein (ATR) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Antitrypsin Related Protein (ATR) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Antitrypsin Related Protein (ATR) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Antitrypsin Related Protein (ATR) Bioactivity
Antibodies NONE Monoclonal Antibody to Antitrypsin Related Protein (ATR) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Antitrypsin Related Protein (ATR) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Antitrypsin Related Protein (ATR) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Antitrypsin Related Protein (ATR) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Antitrypsin Related Protein (ATR) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Antitrypsin Related Protein (ATR) Bioactivity
Antibodies NONE Monoclonal Antibody to Antitrypsin Related Protein (ATR) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Antitrypsin Related Protein (ATR) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Antitrypsin Related Protein (ATR) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Antitrypsin Related Protein (ATR) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Antitrypsin Related Protein (ATR) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Antitrypsin Related Protein (ATR) Bioactivity
Antibodies NONE Monoclonal Antibody to Antitrypsin Related Protein (ATR) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Antitrypsin Related Protein (ATR) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Antitrypsin Related Protein (ATR) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Antitrypsin Related Protein (ATR) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Antitrypsin Related Protein (ATR) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Antitrypsin Related Protein (ATR) Bioactivity
Antibodies NONE Monoclonal Antibody to Antitrypsin Related Protein (ATR) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Antitrypsin Related Protein (ATR) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Antitrypsin Related Protein (ATR) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Antitrypsin Related Protein (ATR) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Antitrypsin Related Protein (ATR) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Antitrypsin Related Protein (ATR) Bioactivity
Antibodies NONE Monoclonal Antibody to Antitrypsin Related Protein (ATR) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Antitrypsin Related Protein (ATR) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Antitrypsin Related Protein (ATR) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Antitrypsin Related Protein (ATR) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Antitrypsin Related Protein (ATR) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Antitrypsin Related Protein (ATR) Bioactivity
Antibodies NONE Monoclonal Antibody to Antitrypsin Related Protein (ATR) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Antitrypsin Related Protein (ATR) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Antitrypsin Related Protein (ATR) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Antitrypsin Related Protein (ATR) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Antitrypsin Related Protein (ATR) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Antitrypsin Related Protein (ATR) Bioactivity
Antibodies NONE Monoclonal Antibody to Antitrypsin Related Protein (ATR) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Antitrypsin Related Protein (ATR) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Antitrypsin Related Protein (ATR) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Antitrypsin Related Protein (ATR) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Antitrypsin Related Protein (ATR) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Antitrypsin Related Protein (ATR) Bioactivity
Antibodies NONE Monoclonal Antibody to Antitrypsin Related Protein (ATR) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Antitrypsin Related Protein (ATR) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Antitrypsin Related Protein (ATR) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Antitrypsin Related Protein (ATR) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Antitrypsin Related Protein (ATR) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Antitrypsin Related Protein (ATR) Bioactivity
Antibodies NONE Monoclonal Antibody to Antitrypsin Related Protein (ATR) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Antitrypsin Related Protein (ATR) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Antitrypsin Related Protein (ATR) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Antitrypsin Related Protein (ATR) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Antitrypsin Related Protein (ATR) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Antitrypsin Related Protein (ATR) Bioactivity
Antibodies NONE Monoclonal Antibody to Antitrypsin Related Protein (ATR) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Antitrypsin Related Protein (ATR) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Antitrypsin Related Protein (ATR) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Antitrypsin Related Protein (ATR) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Antitrypsin Related Protein (ATR) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Antitrypsin Related Protein (ATR) Bioactivity
Antibodies NONE Monoclonal Antibody to Antitrypsin Related Protein (ATR) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Antitrypsin Related Protein (ATR) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Antitrypsin Related Protein (ATR) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Antitrypsin Related Protein (ATR) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Antitrypsin Related Protein (ATR) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Antitrypsin Related Protein (ATR) Bioactivity
Antibodies NONE Monoclonal Antibody to Antitrypsin Related Protein (ATR) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Antitrypsin Related Protein (ATR) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Antitrypsin Related Protein (ATR) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Antitrypsin Related Protein (ATR) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Antitrypsin Related Protein (ATR) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Antitrypsin Related Protein (ATR) Bioactivity
Antibodies NONE Monoclonal Antibody to Antitrypsin Related Protein (ATR) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Antitrypsin Related Protein (ATR) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Antitrypsin Related Protein (ATR) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Antitrypsin Related Protein (ATR) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Antitrypsin Related Protein (ATR) CLIA assay for Antigen Detection

Reference

"Molecular structure and sequence homology of a gene related to alpha 1-antitrypsin in the human genome."
Genomics 2:165-173(1988) [PubMed] [Europe PMC] [Abstract]

"Molecular linkage of the human alpha 1-antitrypsin and corticosteroid-binding globulin genes on chromosome 14q32.1."
Mamm. Genome 8:913-916(1997) [PubMed] [Europe PMC] [Abstract]

"Sequence diversity at the proximal 14q32.1 SERPIN subcluster: evidence for natural selection favoring the pseudogenization of SERPINA2."
Mol. Biol. Evol. 24:587-598(2007) [PubMed] [Europe PMC] [Abstract]

"SERPINA2 is a novel gene with a divergent function from SERPINA1."
PLoS ONE 8:E66889-E66889(2013) [PubMed] [Europe PMC] [Abstract]