Glutamine synthetase (GS)
GLNS; GLUL; Glutamate-Ammonia Ligase; Glutamate decarboxylase
Glutamine is a main source of energy and is involved in cell proliferation, inhibition of apoptosis, and cell signaling. Fetal glutamine requirements are very high and depend largely on active glutamine synthesis and the release of glutamine into the fetal circulation by the placenta. Glutamine synthetase belongs to the glutamine synthetase family. It catalyzes the synthesis of glutamine from glutamate and ammonia. Glutamine is a main source of energy and is involved in cell proliferation, inhibition of apoptosis, and cell signaling. This gene is expressed during early fetal stages, and plays an important role in controlling body pH by removing ammonia from circulation. Mutations in this gene are associated with congenital glutamine deficiency. Several alternatively spliced transcript variants have been found for this gene.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | T024Hu01 | Recombinant Glutamine synthetase (GS) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Glutamine synthetase (GS) | Bioactivity | |
| Antibodies | MT024Hu21 | Monoclonal Antibody to Glutamine synthetase (GS) | WB; IHC; ICC; IP. |
| PT024Hu01 | Polyclonal Antibody to Glutamine synthetase (GS) | WB; IHC; ICC; IF. | |
| LT024Hu71 | Biotin Linked-Polyclonal Antibody to Glutamine synthetase (GS) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Glutamine synthetase (GS) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Glutamine synthetase (GS) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Glutamine synthetase (GS) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Glutamine synthetase (GS) | Flow Cytometry;ICC/IF | |
| Assay Kits | KET024Hu | ELISA Kit for Glutamine synthetase (GS) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Glutamine synthetase (GS) | CLIA assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | T024Mu01 | Recombinant Glutamine synthetase (GS) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Glutamine synthetase (GS) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Glutamine synthetase (GS) | WB; IHC; ICC; IP. |
| PT024Mu01 | Polyclonal Antibody to Glutamine synthetase (GS) | WB; IHC; ICC; IF. | |
| LT024Mu71 | Biotin Linked-Polyclonal Antibody to Glutamine synthetase (GS) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Glutamine synthetase (GS) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Glutamine synthetase (GS) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Glutamine synthetase (GS) | Flow Cytometry | |
| LT024Mu81 | FITC Linked-Polyclonal Antibody to Glutamine synthetase (GS) | Flow Cytometry;ICC/IF | |
| Assay Kits | KET024Mu | ELISA Kit for Glutamine synthetase (GS) | Enzyme-linked immunosorbent assay for Antigen Detection |
| KCT024Mu | CLIA kit for Glutamine synthetase (GS) | CLIA assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | T024Ra01 | Recombinant Glutamine synthetase (GS) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Glutamine synthetase (GS) | Bioactivity | |
| Antibodies | MT024Ra21 | Monoclonal Antibody to Glutamine synthetase (GS) | WB; IHC; ICC; IP. |
| PT024Ra01 | Polyclonal Antibody to Glutamine synthetase (GS) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Glutamine synthetase (GS) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Glutamine synthetase (GS) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Glutamine synthetase (GS) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Glutamine synthetase (GS) | Flow Cytometry | |
| LT024Ra81 | FITC Linked-Polyclonal Antibody to Glutamine synthetase (GS) | Flow Cytometry;ICC/IF | |
| Assay Kits | KET024Ra | ELISA Kit for Glutamine synthetase (GS) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Glutamine synthetase (GS) | CLIA assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Glutamine synthetase (GS) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Glutamine synthetase (GS) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Glutamine synthetase (GS) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Glutamine synthetase (GS) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Glutamine synthetase (GS) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Glutamine synthetase (GS) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Glutamine synthetase (GS) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Glutamine synthetase (GS) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Glutamine synthetase (GS) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Glutamine synthetase (GS) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Glutamine synthetase (GS) | CLIA assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Glutamine synthetase (GS) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Glutamine synthetase (GS) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Glutamine synthetase (GS) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Glutamine synthetase (GS) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Glutamine synthetase (GS) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Glutamine synthetase (GS) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Glutamine synthetase (GS) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Glutamine synthetase (GS) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Glutamine synthetase (GS) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Glutamine synthetase (GS) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Glutamine synthetase (GS) | CLIA assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Glutamine synthetase (GS) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Glutamine synthetase (GS) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Glutamine synthetase (GS) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Glutamine synthetase (GS) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Glutamine synthetase (GS) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Glutamine synthetase (GS) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Glutamine synthetase (GS) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Glutamine synthetase (GS) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Glutamine synthetase (GS) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Glutamine synthetase (GS) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Glutamine synthetase (GS) | CLIA assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Glutamine synthetase (GS) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Glutamine synthetase (GS) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Glutamine synthetase (GS) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Glutamine synthetase (GS) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Glutamine synthetase (GS) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Glutamine synthetase (GS) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Glutamine synthetase (GS) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Glutamine synthetase (GS) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Glutamine synthetase (GS) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Glutamine synthetase (GS) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Glutamine synthetase (GS) | CLIA assay for Antigen Detection |
Organism species: Chicken (Gallus)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Glutamine synthetase (GS) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Glutamine synthetase (GS) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Glutamine synthetase (GS) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Glutamine synthetase (GS) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Glutamine synthetase (GS) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Glutamine synthetase (GS) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Glutamine synthetase (GS) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Glutamine synthetase (GS) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Glutamine synthetase (GS) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Glutamine synthetase (GS) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Glutamine synthetase (GS) | CLIA assay for Antigen Detection |
Organism species: Ovis aries; Ovine (Sheep)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Glutamine synthetase (GS) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Glutamine synthetase (GS) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Glutamine synthetase (GS) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Glutamine synthetase (GS) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Glutamine synthetase (GS) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Glutamine synthetase (GS) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Glutamine synthetase (GS) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Glutamine synthetase (GS) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Glutamine synthetase (GS) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Glutamine synthetase (GS) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Glutamine synthetase (GS) | CLIA assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Glutamine synthetase (GS) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Glutamine synthetase (GS) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Glutamine synthetase (GS) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Glutamine synthetase (GS) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Glutamine synthetase (GS) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Glutamine synthetase (GS) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Glutamine synthetase (GS) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Glutamine synthetase (GS) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Glutamine synthetase (GS) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Glutamine synthetase (GS) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Glutamine synthetase (GS) | CLIA assay for Antigen Detection |
Organism species: Cavia (Guinea pig )
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Glutamine synthetase (GS) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Glutamine synthetase (GS) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Glutamine synthetase (GS) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Glutamine synthetase (GS) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Glutamine synthetase (GS) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Glutamine synthetase (GS) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Glutamine synthetase (GS) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Glutamine synthetase (GS) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Glutamine synthetase (GS) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Glutamine synthetase (GS) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Glutamine synthetase (GS) | CLIA assay for Antigen Detection |
Organism species: Equus caballus; Equine (Horse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Glutamine synthetase (GS) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Glutamine synthetase (GS) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Glutamine synthetase (GS) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Glutamine synthetase (GS) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Glutamine synthetase (GS) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Glutamine synthetase (GS) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Glutamine synthetase (GS) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Glutamine synthetase (GS) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Glutamine synthetase (GS) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Glutamine synthetase (GS) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Glutamine synthetase (GS) | CLIA assay for Antigen Detection |
Organism species: Capra hircus; Caprine (Goat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Glutamine synthetase (GS) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Glutamine synthetase (GS) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Glutamine synthetase (GS) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Glutamine synthetase (GS) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Glutamine synthetase (GS) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Glutamine synthetase (GS) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Glutamine synthetase (GS) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Glutamine synthetase (GS) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Glutamine synthetase (GS) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Glutamine synthetase (GS) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Glutamine synthetase (GS) | CLIA assay for Antigen Detection |
Organism species: Pan-species (General)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Glutamine synthetase (GS) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Glutamine synthetase (GS) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Glutamine synthetase (GS) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Glutamine synthetase (GS) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Glutamine synthetase (GS) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Glutamine synthetase (GS) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Glutamine synthetase (GS) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Glutamine synthetase (GS) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Glutamine synthetase (GS) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Glutamine synthetase (GS) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Glutamine synthetase (GS) | CLIA assay for Antigen Detection |
Reference
"Sequence of a human glutamine synthetase cDNA."
Nucleic Acids Res. 15:6293-6293(1987) [PubMed] [Europe PMC] [Abstract]
"cDNA sequence of the long mRNA for human glutamine synthase."
Biochim. Biophys. Acta 1090:249-251(1991) [PubMed] [Europe PMC] [Abstract]
"Overexpression of glutamine synthetase in human primary liver cancer."
Gastroenterology 106:1312-1320(1994) [PubMed] [Europe PMC] [Abstract]
"The full-ORF clone resource of the German cDNA consortium."
BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
"The DNA sequence and biological annotation of human chromosome 1."
Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Glutamine synthetase isolated from human brain: octameric structure and homology of partial primary structure with human liver glutamine synthetase."
Biochemistry (Mosc.) 67:1012-1020(2002) [PubMed] [Europe PMC] [Abstract]
"Glutamine synthetase is essential for proliferation of fetal skin fibroblasts."
Arch. Biochem. Biophys. 478:96-102(2008) [PubMed] [Europe PMC] [Abstract]
"Wnt and steroid pathways control glutamate signalling by regulating glutamine synthetase activity in osteoblastic cells."
Bone 43:483-493(2008) [PubMed] [Europe PMC] [Abstract]
"Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
"Initial characterization of the human central proteome."
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
"Congenital glutamine deficiency with glutamine synthetase mutations."
N. Engl. J. Med. 353:1926-1933(2005) [PubMed] [Europe PMC] [Abstract]