Metallothionein 1E (MT1E)

MTD

SPN	S990
HGNC	7397
MGI	97171
PubMed	22843066
UniProt	P04732
Wiki	MT1E

Metallothionein-1E is a protein encoded by the MT1E gene. Metallothionein (MT) is a family of cysteine-rich, low molecular weight (MW ranging from 3500 to 14000 Da) proteins. MTs have the capacity to bind both physiological (such as zinc, copper, selenium) and xenobiotic (such as cadmium, mercury, silver, arsenic) heavy metals through the thiol group of its cysteine residues, which represents nearly the 30% of its amino acidic residues.
MT was discovered in 1957 by Vallee and Margoshe from purification of a Cd-binding protein from horse (equine) renal cortex . MTs function is not clear, but experimental data suggest MTs may provide protection against metal toxicity, be involved in regulation of physiological metals (Zn and Cu) and provide protection against oxidative stress.

Organism species: Homo sapiens (Human)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	S990Hu01	Recombinant Metallothionein 1E (MT1E)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Metallothionein 1E (MT1E)	Bioactivity
Antibodies	MS990Hu21	Monoclonal Antibody to Metallothionein 1E (MT1E)	WB; IHC; ICC; IP.
	PS990Hu01	Polyclonal Antibody to Metallothionein 1E (MT1E)	WB; IHC; ICC; IF.
	LS990Hu71	Biotin Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	Flow Cytometry
	LS990Hu81	FITC Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	Flow Cytometry;ICC/IF
Assay Kits	KES990Hu	ELISA Kit for Metallothionein 1E (MT1E)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Metallothionein 1E (MT1E)	CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Metallothionein 1E (MT1E)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Metallothionein 1E (MT1E)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Metallothionein 1E (MT1E)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Metallothionein 1E (MT1E)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Metallothionein 1E (MT1E)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Metallothionein 1E (MT1E)	CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Metallothionein 1E (MT1E)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Metallothionein 1E (MT1E)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Metallothionein 1E (MT1E)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Metallothionein 1E (MT1E)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Metallothionein 1E (MT1E)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Metallothionein 1E (MT1E)	CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Metallothionein 1E (MT1E)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Metallothionein 1E (MT1E)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Metallothionein 1E (MT1E)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Metallothionein 1E (MT1E)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Metallothionein 1E (MT1E)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Metallothionein 1E (MT1E)	CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Metallothionein 1E (MT1E)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Metallothionein 1E (MT1E)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Metallothionein 1E (MT1E)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Metallothionein 1E (MT1E)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Metallothionein 1E (MT1E)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Metallothionein 1E (MT1E)	CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Metallothionein 1E (MT1E)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Metallothionein 1E (MT1E)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Metallothionein 1E (MT1E)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Metallothionein 1E (MT1E)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Metallothionein 1E (MT1E)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Metallothionein 1E (MT1E)	CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Metallothionein 1E (MT1E)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Metallothionein 1E (MT1E)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Metallothionein 1E (MT1E)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Metallothionein 1E (MT1E)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Metallothionein 1E (MT1E)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Metallothionein 1E (MT1E)	CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Metallothionein 1E (MT1E)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Metallothionein 1E (MT1E)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Metallothionein 1E (MT1E)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Metallothionein 1E (MT1E)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Metallothionein 1E (MT1E)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Metallothionein 1E (MT1E)	CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Metallothionein 1E (MT1E)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Metallothionein 1E (MT1E)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Metallothionein 1E (MT1E)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Metallothionein 1E (MT1E)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Metallothionein 1E (MT1E)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Metallothionein 1E (MT1E)	CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Metallothionein 1E (MT1E)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Metallothionein 1E (MT1E)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Metallothionein 1E (MT1E)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Metallothionein 1E (MT1E)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Metallothionein 1E (MT1E)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Metallothionein 1E (MT1E)	CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Metallothionein 1E (MT1E)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Metallothionein 1E (MT1E)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Metallothionein 1E (MT1E)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Metallothionein 1E (MT1E)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Metallothionein 1E (MT1E)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Metallothionein 1E (MT1E)	CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Metallothionein 1E (MT1E)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Metallothionein 1E (MT1E)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Metallothionein 1E (MT1E)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Metallothionein 1E (MT1E)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Metallothionein 1E (MT1E)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Metallothionein 1E (MT1E)	CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Metallothionein 1E (MT1E)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Metallothionein 1E (MT1E)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Metallothionein 1E (MT1E)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Metallothionein 1E (MT1E)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Metallothionein 1E (MT1E)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Metallothionein 1E (MT1E)	CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Metallothionein 1E (MT1E)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Metallothionein 1E (MT1E)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Metallothionein 1E (MT1E)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Metallothionein 1E (MT1E)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Metallothionein 1E (MT1E)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Metallothionein 1E (MT1E)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Metallothionein 1E (MT1E)	CLIA assay for Antigen Detection

Reference

"Structure and expression of two human metallothionein-I isoform genes and a related pseudogene."
J. Biol. Chem. 260:7731-7737(1985) [PubMed] [Europe PMC] [Abstract]

"Amino acid sequence determination."
Methods Enzymol. 205:421-426(1991) [PubMed] [Europe PMC] [Abstract]

"The sequence and analysis of duplication-rich human chromosome 16."
Nature 432:988-994(2004) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Induction by zinc of specific metallothionein isoforms in human monocytes."
Eur. J. Biochem. 220:105-110(1994) [PubMed] [Europe PMC] [Abstract]