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Relaxin 2 (RLN2)

H2; RLXH2; Relaxin H2; Prorelaxin H2; Relaxin,Ovarian,Of Pregnancy; Prorelaxin H2

SPN S906
HGNC 10027
MGI 97931
PubMed 23141816
UniProt P04090
Relaxins are known endocrine and autocrine/paracrine hormones, belonging to the insulin gene superfamily. In the human there are three non-allelic relaxin genes, RLN1, RLN2 and RLN3.RLN2 consists of an A chain and a B chain but their cleavage sites are not definitely described yet. Relaxin is produced by the ovary, and targets the mammalian reproductive system to ripen the cervix, elongate the pubic symphysis and inhibit uterine contraction. It may have additional roles in enhancing sperm motility, regulating blood pressure, controlling heart rate and releasing oxytocin and vasopressin. There are two alternatively spliced transcript variants encoding different isoforms described for this gene. Serelaxin, recombinant human relaxin-2, is a vasoactive peptide hormone with many biological and haemodynamic effects.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Relaxin 2 (RLN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Relaxin 2 (RLN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Relaxin 2 (RLN2) WB; IHC; ICC; IP.
PS906Hu01 Polyclonal Antibody to Relaxin 2 (RLN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Relaxin 2 (RLN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Relaxin 2 (RLN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Relaxin 2 (RLN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Relaxin 2 (RLN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Relaxin 2 (RLN2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Relaxin 2 (RLN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Relaxin 2 (RLN2) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Relaxin 2 (RLN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Relaxin 2 (RLN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Relaxin 2 (RLN2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Relaxin 2 (RLN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Relaxin 2 (RLN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Relaxin 2 (RLN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Relaxin 2 (RLN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Relaxin 2 (RLN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Relaxin 2 (RLN2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Relaxin 2 (RLN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Relaxin 2 (RLN2) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Relaxin 2 (RLN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Relaxin 2 (RLN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Relaxin 2 (RLN2) WB; IHC; ICC; IP.
PS906Ra01 Polyclonal Antibody to Relaxin 2 (RLN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Relaxin 2 (RLN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Relaxin 2 (RLN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Relaxin 2 (RLN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Relaxin 2 (RLN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Relaxin 2 (RLN2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Relaxin 2 (RLN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Relaxin 2 (RLN2) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Relaxin 2 (RLN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Relaxin 2 (RLN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Relaxin 2 (RLN2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Relaxin 2 (RLN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Relaxin 2 (RLN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Relaxin 2 (RLN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Relaxin 2 (RLN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Relaxin 2 (RLN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Relaxin 2 (RLN2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Relaxin 2 (RLN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Relaxin 2 (RLN2) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Relaxin 2 (RLN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Relaxin 2 (RLN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Relaxin 2 (RLN2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Relaxin 2 (RLN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Relaxin 2 (RLN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Relaxin 2 (RLN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Relaxin 2 (RLN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Relaxin 2 (RLN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Relaxin 2 (RLN2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Relaxin 2 (RLN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Relaxin 2 (RLN2) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Relaxin 2 (RLN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Relaxin 2 (RLN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Relaxin 2 (RLN2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Relaxin 2 (RLN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Relaxin 2 (RLN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Relaxin 2 (RLN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Relaxin 2 (RLN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Relaxin 2 (RLN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Relaxin 2 (RLN2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Relaxin 2 (RLN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Relaxin 2 (RLN2) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Relaxin 2 (RLN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Relaxin 2 (RLN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Relaxin 2 (RLN2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Relaxin 2 (RLN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Relaxin 2 (RLN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Relaxin 2 (RLN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Relaxin 2 (RLN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Relaxin 2 (RLN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Relaxin 2 (RLN2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Relaxin 2 (RLN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Relaxin 2 (RLN2) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Relaxin 2 (RLN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Relaxin 2 (RLN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Relaxin 2 (RLN2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Relaxin 2 (RLN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Relaxin 2 (RLN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Relaxin 2 (RLN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Relaxin 2 (RLN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Relaxin 2 (RLN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Relaxin 2 (RLN2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Relaxin 2 (RLN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Relaxin 2 (RLN2) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Relaxin 2 (RLN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Relaxin 2 (RLN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Relaxin 2 (RLN2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Relaxin 2 (RLN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Relaxin 2 (RLN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Relaxin 2 (RLN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Relaxin 2 (RLN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Relaxin 2 (RLN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Relaxin 2 (RLN2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Relaxin 2 (RLN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Relaxin 2 (RLN2) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Relaxin 2 (RLN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Relaxin 2 (RLN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Relaxin 2 (RLN2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Relaxin 2 (RLN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Relaxin 2 (RLN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Relaxin 2 (RLN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Relaxin 2 (RLN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Relaxin 2 (RLN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Relaxin 2 (RLN2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Relaxin 2 (RLN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Relaxin 2 (RLN2) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Relaxin 2 (RLN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Relaxin 2 (RLN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Relaxin 2 (RLN2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Relaxin 2 (RLN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Relaxin 2 (RLN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Relaxin 2 (RLN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Relaxin 2 (RLN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Relaxin 2 (RLN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Relaxin 2 (RLN2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Relaxin 2 (RLN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Relaxin 2 (RLN2) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Relaxin 2 (RLN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Relaxin 2 (RLN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Relaxin 2 (RLN2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Relaxin 2 (RLN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Relaxin 2 (RLN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Relaxin 2 (RLN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Relaxin 2 (RLN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Relaxin 2 (RLN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Relaxin 2 (RLN2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Relaxin 2 (RLN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Relaxin 2 (RLN2) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Relaxin 2 (RLN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Relaxin 2 (RLN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Relaxin 2 (RLN2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Relaxin 2 (RLN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Relaxin 2 (RLN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Relaxin 2 (RLN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Relaxin 2 (RLN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Relaxin 2 (RLN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Relaxin 2 (RLN2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Relaxin 2 (RLN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Relaxin 2 (RLN2) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Relaxin 2 (RLN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Relaxin 2 (RLN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Relaxin 2 (RLN2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Relaxin 2 (RLN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Relaxin 2 (RLN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Relaxin 2 (RLN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Relaxin 2 (RLN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Relaxin 2 (RLN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Relaxin 2 (RLN2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Relaxin 2 (RLN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Relaxin 2 (RLN2) CLIA assay for Antigen Detection

Reference

"Relaxin gene expression in human ovaries and the predicted structure of a human preprorelaxin by analysis of cDNA clones."
EMBO J. 3:2333-2339(1984) [PubMed] [Europe PMC] [Abstract]

"DNA sequence and analysis of human chromosome 9."
Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Expression of human relaxin genes: characterization of a novel alternatively-spliced human relaxin mRNA species."
Mol. Cell. Endocrinol. 118:85-94(1996) [PubMed] [Europe PMC] [Abstract]

"Analysis of the 5'-upstream regions of the human relaxin H1 and H2 genes and their chromosomal localization on chromosome 9p24.1 by radiation hybrid and breakpoint mapping."
J. Mol. Endocrinol. 23:355-365(1999) [PubMed] [Europe PMC] [Abstract]

"Human seminal relaxin is a product of the same gene as human luteal relaxin."
Endocrinology 130:2660-2668(1992) [PubMed] [Europe PMC] [Abstract]

"Structural characterization by mass spectrometry of native and recombinant human relaxin."
Biomed. Environ. Mass Spectrom. 19:655-664(1990) [PubMed] [Europe PMC] [Abstract]

"Total synthesis of human relaxin and human relaxin derivatives by solid-phase peptide synthesis and site-directed chain combination."
J. Biol. Chem. 266:10754-10761(1991) [PubMed] [Europe PMC] [Abstract]

"X-ray structure of human relaxin at 1.5 A. Comparison to insulin and implications for receptor binding determinants."
J. Mol. Biol. 221:15-21(1991) [PubMed] [Europe PMC] [Abstract]

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