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Insulin Like Protein 5 (INSL5)

Insulin gene superfamily hormones regulate cell growth, metabolism, and tissue-specific functions. Members of this family are characterized by a signal peptide, a B chain, a connecting C chain, and an A chain.
By EST database searching for sequences related to relaxin (RLN1), Conklin et al. (1999) identified a cDNA encoding INSL5, also designated ZINS3. The deduced 135-amino acid protein, which shares 59% and 40% sequence identity with mouse Insl5 and human RLN1, respectively, has a dibasic cleavage site between the B and C chains. Northern blot analysis revealed expression of an approximately 1.0-kb transcript in uterus, rectum, and colon. By radiation hybrid analysis and the use of surrounding markers, Conklin et al. (1999) mapped the INSL5 gene to chromosome 1p31.1-p22.3.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins S900Hu01 Recombinant Insulin Like Protein 5 (INSL5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Insulin Like Protein 5 (INSL5) Bioactivity
Antibodies MS900Hu21 Monoclonal Antibody to Insulin Like Protein 5 (INSL5) WB; IHC; ICC; IP.
PS900Hu01 Polyclonal Antibody to Insulin Like Protein 5 (INSL5) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) Flow Cytometry;ICC/IF
Assay Kits KES900Hu ELISA Kit for Insulin Like Protein 5 (INSL5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Insulin Like Protein 5 (INSL5) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins S900Mu01 Recombinant Insulin Like Protein 5 (INSL5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Insulin Like Protein 5 (INSL5) Bioactivity
Antibodies NONE Monoclonal Antibody to Insulin Like Protein 5 (INSL5) WB; IHC; ICC; IP.
PS900Mu01 Polyclonal Antibody to Insulin Like Protein 5 (INSL5) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) Flow Cytometry;ICC/IF
Assay Kits KES900Mu ELISA Kit for Insulin Like Protein 5 (INSL5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Insulin Like Protein 5 (INSL5) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Insulin Like Protein 5 (INSL5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Insulin Like Protein 5 (INSL5) Bioactivity
Antibodies NONE Monoclonal Antibody to Insulin Like Protein 5 (INSL5) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Insulin Like Protein 5 (INSL5) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Insulin Like Protein 5 (INSL5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Insulin Like Protein 5 (INSL5) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Insulin Like Protein 5 (INSL5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Insulin Like Protein 5 (INSL5) Bioactivity
Antibodies NONE Monoclonal Antibody to Insulin Like Protein 5 (INSL5) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Insulin Like Protein 5 (INSL5) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Insulin Like Protein 5 (INSL5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Insulin Like Protein 5 (INSL5) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Insulin Like Protein 5 (INSL5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Insulin Like Protein 5 (INSL5) Bioactivity
Antibodies NONE Monoclonal Antibody to Insulin Like Protein 5 (INSL5) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Insulin Like Protein 5 (INSL5) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Insulin Like Protein 5 (INSL5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Insulin Like Protein 5 (INSL5) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Insulin Like Protein 5 (INSL5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Insulin Like Protein 5 (INSL5) Bioactivity
Antibodies NONE Monoclonal Antibody to Insulin Like Protein 5 (INSL5) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Insulin Like Protein 5 (INSL5) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Insulin Like Protein 5 (INSL5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Insulin Like Protein 5 (INSL5) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Insulin Like Protein 5 (INSL5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Insulin Like Protein 5 (INSL5) Bioactivity
Antibodies NONE Monoclonal Antibody to Insulin Like Protein 5 (INSL5) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Insulin Like Protein 5 (INSL5) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Insulin Like Protein 5 (INSL5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Insulin Like Protein 5 (INSL5) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Insulin Like Protein 5 (INSL5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Insulin Like Protein 5 (INSL5) Bioactivity
Antibodies NONE Monoclonal Antibody to Insulin Like Protein 5 (INSL5) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Insulin Like Protein 5 (INSL5) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Insulin Like Protein 5 (INSL5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Insulin Like Protein 5 (INSL5) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Insulin Like Protein 5 (INSL5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Insulin Like Protein 5 (INSL5) Bioactivity
Antibodies NONE Monoclonal Antibody to Insulin Like Protein 5 (INSL5) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Insulin Like Protein 5 (INSL5) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Insulin Like Protein 5 (INSL5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Insulin Like Protein 5 (INSL5) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Insulin Like Protein 5 (INSL5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Insulin Like Protein 5 (INSL5) Bioactivity
Antibodies NONE Monoclonal Antibody to Insulin Like Protein 5 (INSL5) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Insulin Like Protein 5 (INSL5) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Insulin Like Protein 5 (INSL5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Insulin Like Protein 5 (INSL5) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Insulin Like Protein 5 (INSL5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Insulin Like Protein 5 (INSL5) Bioactivity
Antibodies NONE Monoclonal Antibody to Insulin Like Protein 5 (INSL5) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Insulin Like Protein 5 (INSL5) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Insulin Like Protein 5 (INSL5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Insulin Like Protein 5 (INSL5) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Insulin Like Protein 5 (INSL5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Insulin Like Protein 5 (INSL5) Bioactivity
Antibodies NONE Monoclonal Antibody to Insulin Like Protein 5 (INSL5) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Insulin Like Protein 5 (INSL5) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Insulin Like Protein 5 (INSL5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Insulin Like Protein 5 (INSL5) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Insulin Like Protein 5 (INSL5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Insulin Like Protein 5 (INSL5) Bioactivity
Antibodies NONE Monoclonal Antibody to Insulin Like Protein 5 (INSL5) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Insulin Like Protein 5 (INSL5) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Insulin Like Protein 5 (INSL5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Insulin Like Protein 5 (INSL5) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Insulin Like Protein 5 (INSL5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Insulin Like Protein 5 (INSL5) Bioactivity
Antibodies NONE Monoclonal Antibody to Insulin Like Protein 5 (INSL5) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Insulin Like Protein 5 (INSL5) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Insulin Like Protein 5 (INSL5) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Insulin Like Protein 5 (INSL5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Insulin Like Protein 5 (INSL5) CLIA assay for Antigen Detection

Reference

"Identification of INSL5, a new member of the insulin superfamily."
Genomics 60:50-56(1999) [PubMed] [Europe PMC] [Abstract]

"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence and biological annotation of human chromosome 1."
Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Signal peptide prediction based on analysis of experimentally verified cleavage sites."
Protein Sci. 13:2819-2824(2004) [PubMed] [Europe PMC] [Abstract]

"INSL5 is a high affinity specific agonist for GPCR142 (GPR100)."
J. Biol. Chem. 280:292-300(2005) [PubMed] [Europe PMC] [Abstract]

"Synthesis, conformation, and activity of human insulin-like peptide 5 (INSL5)."
ChemBioChem 9:1816-1822(2008) [PubMed] [Europe PMC] [Abstract]

"Structure of human insulin-like peptide 5 and characterization of conserved hydrogen bonds and electrostatic interactions within the relaxin framework."
Biochem. J. 419:619-627(2009) [PubMed] [Europe PMC] [Abstract]