Insulin Receptor Substrate 2 (IRS2)
Insulin receptor substrate 2 is a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment.. Mice lacking IRS2 have a diabetic phenotype as well as a 40% reduction in brain mass.Insulin receptor substrate-2 (IRS-2) is a multisite docking protein implicated in mitogenic signaling after activation of the insulin and insulin-like growth factor (IGF)-I receptors.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | S895Hu01 | Recombinant Insulin Receptor Substrate 2 (IRS2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Insulin Receptor Substrate 2 (IRS2) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | WB; IHC; ICC; IP. |
| PS895Hu01 | Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | Flow Cytometry;ICC/IF | |
| Assay Kits | KES895Hu | ELISA Kit for Insulin Receptor Substrate 2 (IRS2) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Insulin Receptor Substrate 2 (IRS2) | CLIA assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | S895Mu02 | Recombinant Insulin Receptor Substrate 2 (IRS2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Insulin Receptor Substrate 2 (IRS2) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | WB; IHC; ICC; IP. |
| PS895Mu01 | Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | Flow Cytometry;ICC/IF | |
| Assay Kits | KES895Mu | ELISA Kit for Insulin Receptor Substrate 2 (IRS2) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Insulin Receptor Substrate 2 (IRS2) | CLIA assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Insulin Receptor Substrate 2 (IRS2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Insulin Receptor Substrate 2 (IRS2) | Bioactivity | |
| Antibodies | MS895Ra21 | Monoclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | WB; IHC; ICC; IP. |
| PS895Ra01 | Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | Flow Cytometry;ICC/IF | |
| Assay Kits | KES895Ra | ELISA Kit for Insulin Receptor Substrate 2 (IRS2) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Insulin Receptor Substrate 2 (IRS2) | CLIA assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Insulin Receptor Substrate 2 (IRS2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Insulin Receptor Substrate 2 (IRS2) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Insulin Receptor Substrate 2 (IRS2) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Insulin Receptor Substrate 2 (IRS2) | CLIA assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Insulin Receptor Substrate 2 (IRS2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Insulin Receptor Substrate 2 (IRS2) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Insulin Receptor Substrate 2 (IRS2) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Insulin Receptor Substrate 2 (IRS2) | CLIA assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Insulin Receptor Substrate 2 (IRS2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Insulin Receptor Substrate 2 (IRS2) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Insulin Receptor Substrate 2 (IRS2) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Insulin Receptor Substrate 2 (IRS2) | CLIA assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Insulin Receptor Substrate 2 (IRS2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Insulin Receptor Substrate 2 (IRS2) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Insulin Receptor Substrate 2 (IRS2) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Insulin Receptor Substrate 2 (IRS2) | CLIA assay for Antigen Detection |
Organism species: Chicken (Gallus)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Insulin Receptor Substrate 2 (IRS2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Insulin Receptor Substrate 2 (IRS2) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Insulin Receptor Substrate 2 (IRS2) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Insulin Receptor Substrate 2 (IRS2) | CLIA assay for Antigen Detection |
Organism species: Ovis aries; Ovine (Sheep)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Insulin Receptor Substrate 2 (IRS2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Insulin Receptor Substrate 2 (IRS2) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Insulin Receptor Substrate 2 (IRS2) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Insulin Receptor Substrate 2 (IRS2) | CLIA assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Insulin Receptor Substrate 2 (IRS2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Insulin Receptor Substrate 2 (IRS2) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Insulin Receptor Substrate 2 (IRS2) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Insulin Receptor Substrate 2 (IRS2) | CLIA assay for Antigen Detection |
Organism species: Cavia (Guinea pig )
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Insulin Receptor Substrate 2 (IRS2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Insulin Receptor Substrate 2 (IRS2) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Insulin Receptor Substrate 2 (IRS2) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Insulin Receptor Substrate 2 (IRS2) | CLIA assay for Antigen Detection |
Organism species: Equus caballus; Equine (Horse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Insulin Receptor Substrate 2 (IRS2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Insulin Receptor Substrate 2 (IRS2) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Insulin Receptor Substrate 2 (IRS2) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Insulin Receptor Substrate 2 (IRS2) | CLIA assay for Antigen Detection |
Organism species: Capra hircus; Caprine (Goat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Insulin Receptor Substrate 2 (IRS2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Insulin Receptor Substrate 2 (IRS2) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Insulin Receptor Substrate 2 (IRS2) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Insulin Receptor Substrate 2 (IRS2) | CLIA assay for Antigen Detection |
Organism species: Pan-species (General)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Insulin Receptor Substrate 2 (IRS2) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Insulin Receptor Substrate 2 (IRS2) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Insulin Receptor Substrate 2 (IRS2) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Insulin Receptor Substrate 2 (IRS2) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Insulin Receptor Substrate 2 (IRS2) | CLIA assay for Antigen Detection |
Reference
"14-3-3 protein binds to insulin receptor substrate-1, one of the binding sites of which is in the phosphotyrosine binding domain."
J. Biol. Chem. 272:25267-25274(1997) [PubMed] [Europe PMC] [Abstract]
"Human insulin receptor substrate-2 (IRS-2) is a primary progesterone response gene."
Mol. Endocrinol. 13:485-494(1999) [PubMed] [Europe PMC] [Abstract]
"The DNA sequence and analysis of human chromosome 13."
Nature 428:522-528(2004) [PubMed] [Europe PMC] [Abstract]
"Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
"A probability-based approach for high-throughput protein phosphorylation analysis and site localization."
Nat. Biotechnol. 24:1285-1292(2006) [PubMed] [Europe PMC] [Abstract]
"Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis."
J. Proteome Res. 7:1346-1351(2008) [PubMed] [Europe PMC] [Abstract]
"Phosphoproteome of resting human platelets."
J. Proteome Res. 7:526-534(2008) [PubMed] [Europe PMC] [Abstract]
"A quantitative atlas of mitotic phosphorylation."
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
"Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
"Large-scale proteomics analysis of the human kinome."
Mol. Cell. Proteomics 8:1751-1764(2009) [PubMed] [Europe PMC] [Abstract]
"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
"Initial characterization of the human central proteome."
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
"System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
"Complex haplotypes of IRS2 gene are associated with severe obesity and reveal heterogeneity in the effect of Gly1057Asp mutation."
Hum. Genet. 113:34-43(2003) [PubMed] [Europe PMC] [Abstract]