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5'-Nucleotidase, Cytosolic II (NT5C2)

NT5B; PNT5; GMP; cN-II; NT5CP; Purine 5' Nucleotidase; 5'-Nucleotidase(Purine),Cytosolic Type B; Cytosolic purine 5'-nucleotidase

5' nucleotidases cleave off the phosphate from the 5' end of the sugar moiety. They can be classified into various kinds depending on their substrate preferences and subcellular localization. Membrane bound 5' nucleotidases displays specificity towards adenosine monophosphates and are predominantly involved in the salvage of preformed nucleotides and in signal transduction cascades involving purinergic receptors.Purine 5-prime-nucleotidase (EC 3.1.3.5) preferentially hydrolyzes inosine 5-prime-monophosphate (IMP) and other purine nucleotides, and is allosterically activated by various compounds, including ATP. NT5C2 is exclusively located in the cytoplasmic matrix of cells and may have a critical role in the maintenance of a constant composition of intracellular purine/pyrimidine nucleotides in cooperation with other nucleotidases.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPS848Hu01 Recombinant 5'-Nucleotidase, Cytosolic II (NT5C2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAS848Hu01 Monoclonal Antibody to 5'-Nucleotidase, Cytosolic II (NT5C2) WB; IHC; ICC; IP.
PAS848Hu01 Polyclonal Antibody to 5'-Nucleotidase, Cytosolic II (NT5C2) WB; IHC; ICC; IF.
Assay Kits CLS848Hu01 CLIA Kit for 5'-Nucleotidase, Cytosolic II (NT5C2) CLIA assay for Antigen Detection
ELS848Hu01 ELISA Kit for 5'-Nucleotidase, Cytosolic II (NT5C2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPS848Mu01 Recombinant 5'-Nucleotidase, Cytosolic II (NT5C2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAS848Mu01 Monoclonal Antibody to 5'-Nucleotidase, Cytosolic II (NT5C2) WB; IHC; ICC; IP.
PAS848Mu01 Polyclonal Antibody to 5'-Nucleotidase, Cytosolic II (NT5C2) WB; IHC; ICC; IF.
Assay Kits CLS848Mu01 CLIA Kit for 5'-Nucleotidase, Cytosolic II (NT5C2) CLIA assay for Antigen Detection
ELS848Mu01 ELISA Kit for 5'-Nucleotidase, Cytosolic II (NT5C2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPS848Ra01 Recombinant 5'-Nucleotidase, Cytosolic II (NT5C2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAS848Ra01 Monoclonal Antibody to 5'-Nucleotidase, Cytosolic II (NT5C2) WB; IHC; ICC; IP.
PAS848Ra01 Polyclonal Antibody to 5'-Nucleotidase, Cytosolic II (NT5C2) WB; IHC; ICC; IF.
Assay Kits CLS848Ra01 CLIA Kit for 5'-Nucleotidase, Cytosolic II (NT5C2) CLIA assay for Antigen Detection
ELS848Ra01 ELISA Kit for 5'-Nucleotidase, Cytosolic II (NT5C2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPS848Ca01 Recombinant 5'-Nucleotidase, Cytosolic II (NT5C2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAS848Ca01 Monoclonal Antibody to 5'-Nucleotidase, Cytosolic II (NT5C2) WB; IHC; ICC; IP.
PAS848Ca01 Polyclonal Antibody to 5'-Nucleotidase, Cytosolic II (NT5C2) WB; IHC; ICC; IF.
Assay Kits CLS848Ca01 CLIA Kit for 5'-Nucleotidase, Cytosolic II (NT5C2) CLIA assay for Antigen Detection
ELS848Ca01 ELISA Kit for 5'-Nucleotidase, Cytosolic II (NT5C2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPS848Po01 Recombinant 5'-Nucleotidase, Cytosolic II (NT5C2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAS848Po01 Monoclonal Antibody to 5'-Nucleotidase, Cytosolic II (NT5C2) WB; IHC; ICC; IP.
PAS848Po01 Polyclonal Antibody to 5'-Nucleotidase, Cytosolic II (NT5C2) WB; IHC; ICC; IF.
Assay Kits CLS848Po01 CLIA Kit for 5'-Nucleotidase, Cytosolic II (NT5C2) CLIA assay for Antigen Detection
ELS848Po01 ELISA Kit for 5'-Nucleotidase, Cytosolic II (NT5C2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPS848Bo01 Recombinant 5'-Nucleotidase, Cytosolic II (NT5C2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAS848Bo01 Monoclonal Antibody to 5'-Nucleotidase, Cytosolic II (NT5C2) WB; IHC; ICC; IP.
PAS848Bo01 Polyclonal Antibody to 5'-Nucleotidase, Cytosolic II (NT5C2) WB; IHC; ICC; IF.
Assay Kits CLS848Bo01 CLIA Kit for 5'-Nucleotidase, Cytosolic II (NT5C2) CLIA assay for Antigen Detection
ELS848Bo01 ELISA Kit for 5'-Nucleotidase, Cytosolic II (NT5C2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPS848Rb01 Recombinant 5'-Nucleotidase, Cytosolic II (NT5C2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAS848Rb01 Monoclonal Antibody to 5'-Nucleotidase, Cytosolic II (NT5C2) WB; IHC; ICC; IP.
PAS848Rb01 Polyclonal Antibody to 5'-Nucleotidase, Cytosolic II (NT5C2) WB; IHC; ICC; IF.
Assay Kits CLS848Rb01 CLIA Kit for 5'-Nucleotidase, Cytosolic II (NT5C2) CLIA assay for Antigen Detection
ELS848Rb01 ELISA Kit for 5'-Nucleotidase, Cytosolic II (NT5C2) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPS848Mo01 Recombinant 5'-Nucleotidase, Cytosolic II (NT5C2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAS848Mo01 Monoclonal Antibody to 5'-Nucleotidase, Cytosolic II (NT5C2) WB; IHC; ICC; IP.
PAS848Mo01 Polyclonal Antibody to 5'-Nucleotidase, Cytosolic II (NT5C2) WB; IHC; ICC; IF.
Assay Kits CLS848Mo01 CLIA Kit for 5'-Nucleotidase, Cytosolic II (NT5C2) CLIA assay for Antigen Detection
ELS848Mo01 ELISA Kit for 5'-Nucleotidase, Cytosolic II (NT5C2) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

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Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]

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"Initial characterization of the human central proteome."
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

"Exome sequencing links corticospinal motor neuron disease to common neurodegenerative disorders."
Science 343:506-511(2014) [PubMed] [Europe PMC] [Abstract]

"Crystal structure of human cytosolic 5'-nucleotidase II: insights into allosteric regulation and substrate recognition."
J. Biol. Chem. 282:17828-17836(2007) [PubMed] [Europe PMC] [Abstract]