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Ephrin A1 (EFNA1)

B61; ECKLG; EFL1; EPLG1; LERK1; TNFAIP4; EPH-related receptor tyrosine kinase ligand 1; Tumor necrosis factor alpha-induced protein 4; Immediate early response protein B61

Ephrin-A1 is a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNA class ephrin which binds to the EPHA2, EPHA4, EPHA5, EPHA6, and EPHA7 receptors. Two transcript variants that encode different isoforms were identified through sequence analysis.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPS674Hu01 Recombinant Ephrin A1 (EFNA1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAS674Hu01 Monoclonal Antibody to Ephrin A1 (EFNA1) WB; IHC; ICC; IP.
PAS674Hu01 Polyclonal Antibody to Ephrin A1 (EFNA1) WB; IHC; ICC; IF.
Assay Kits CLS674Hu01 CLIA Kit for Ephrin A1 (EFNA1) CLIA assay for Antigen Detection
ELS674Hu01 ELISA Kit for Ephrin A1 (EFNA1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPS674Mu01 Recombinant Ephrin A1 (EFNA1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAS674Mu01 Monoclonal Antibody to Ephrin A1 (EFNA1) WB; IHC; ICC; IP.
PAS674Mu01 Polyclonal Antibody to Ephrin A1 (EFNA1) WB; IHC; ICC; IF.
Assay Kits CLS674Mu01 CLIA Kit for Ephrin A1 (EFNA1) CLIA assay for Antigen Detection
ELS674Mu01 ELISA Kit for Ephrin A1 (EFNA1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPS674Ra01 Recombinant Ephrin A1 (EFNA1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAS674Ra01 Monoclonal Antibody to Ephrin A1 (EFNA1) WB; IHC; ICC; IP.
PAS674Ra01 Polyclonal Antibody to Ephrin A1 (EFNA1) WB; IHC; ICC; IF.
Assay Kits CLS674Ra01 CLIA Kit for Ephrin A1 (EFNA1) CLIA assay for Antigen Detection
ELS674Ra01 ELISA Kit for Ephrin A1 (EFNA1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPS674Ca01 Recombinant Ephrin A1 (EFNA1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAS674Ca01 Monoclonal Antibody to Ephrin A1 (EFNA1) WB; IHC; ICC; IP.
PAS674Ca01 Polyclonal Antibody to Ephrin A1 (EFNA1) WB; IHC; ICC; IF.
Assay Kits CLS674Ca01 CLIA Kit for Ephrin A1 (EFNA1) CLIA assay for Antigen Detection
ELS674Ca01 ELISA Kit for Ephrin A1 (EFNA1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPS674Po01 Recombinant Ephrin A1 (EFNA1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAS674Po01 Monoclonal Antibody to Ephrin A1 (EFNA1) WB; IHC; ICC; IP.
PAS674Po01 Polyclonal Antibody to Ephrin A1 (EFNA1) WB; IHC; ICC; IF.
Assay Kits CLS674Po01 CLIA Kit for Ephrin A1 (EFNA1) CLIA assay for Antigen Detection
ELS674Po01 ELISA Kit for Ephrin A1 (EFNA1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPS674Bo01 Recombinant Ephrin A1 (EFNA1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAS674Bo01 Monoclonal Antibody to Ephrin A1 (EFNA1) WB; IHC; ICC; IP.
PAS674Bo01 Polyclonal Antibody to Ephrin A1 (EFNA1) WB; IHC; ICC; IF.
Assay Kits CLS674Bo01 CLIA Kit for Ephrin A1 (EFNA1) CLIA assay for Antigen Detection
ELS674Bo01 ELISA Kit for Ephrin A1 (EFNA1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPS674Rb01 Recombinant Ephrin A1 (EFNA1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAS674Rb01 Monoclonal Antibody to Ephrin A1 (EFNA1) WB; IHC; ICC; IP.
PAS674Rb01 Polyclonal Antibody to Ephrin A1 (EFNA1) WB; IHC; ICC; IF.
Assay Kits CLS674Rb01 CLIA Kit for Ephrin A1 (EFNA1) CLIA assay for Antigen Detection
ELS674Rb01 ELISA Kit for Ephrin A1 (EFNA1) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPS674Mo01 Recombinant Ephrin A1 (EFNA1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAS674Mo01 Monoclonal Antibody to Ephrin A1 (EFNA1) WB; IHC; ICC; IP.
PAS674Mo01 Polyclonal Antibody to Ephrin A1 (EFNA1) WB; IHC; ICC; IF.
Assay Kits CLS674Mo01 CLIA Kit for Ephrin A1 (EFNA1) CLIA assay for Antigen Detection
ELS674Mo01 ELISA Kit for Ephrin A1 (EFNA1) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"A novel immediate-early response gene of endothelium is induced by cytokines and encodes a secreted protein."
Mol. Cell. Biol. 10:5830-5838(1990) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence and biological annotation of human chromosome 1."
Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Signal peptide prediction based on analysis of experimentally verified cleavage sites."
Protein Sci. 13:2819-2824(2004) [PubMed] [Europe PMC] [Abstract]

"Ligands for the receptor tyrosine kinases hek and elk: isolation of cDNAs encoding a family of proteins."
Oncogene 10:299-306(1995) [PubMed] [Europe PMC] [Abstract]

"Ephrin-A1 is a negative regulator in glioma through down-regulation of EphA2 and FAK."
Int. J. Oncol. 30:865-871(2007) [PubMed] [Europe PMC] [Abstract]

"Soluble monomeric EphrinA1 is released from tumor cells and is a functional ligand for the EphA2 receptor."
Oncogene 27:7260-7273(2008) [PubMed] [Europe PMC] [Abstract]

"Biological and structural characterization of glycosylation on ephrin-A1, a preferred ligand for EphA2 receptor tyrosine kinase."
J. Biol. Chem. 288:18448-18457(2013) [PubMed] [Europe PMC] [Abstract]

"Ligand recognition by A-class Eph receptors: crystal structures of the EphA2 ligand-binding domain and the EphA2/ephrin-A1 complex."
EMBO Rep. 10:722-728(2009) [PubMed] [Europe PMC] [Abstract]

"Architecture of Eph receptor clusters."
Proc. Natl. Acad. Sci. U.S.A. 107:10860-10865(2010) [PubMed] [Europe PMC] [Abstract]