Ephrin A2 (EFNA2)

ELF-1; EPLG6; HEK7-L; LERK6; EPH-related receptor tyrosine kinase ligand 6; HEK7 ligand

SPN	S673
HGNC	3222
MGI	102707
RGD	620389
UniProt	O43921
Wiki	EFNA2

Ephrin-A2 is a member of the ephrin family. The protein is composed of a signal sequence, a receptor-binding region, a spacer region, and a hydrophobic region. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system.

Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. Posttranslational modifications determine whether this protein localizes to the nucleus or the cytoplasm.

Organism species: Homo sapiens (Human)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPS673Hu01	Recombinant Ephrin A2 (EFNA2)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAS673Hu01	Monoclonal Antibody to Ephrin A2 (EFNA2)	WB; IHC; ICC; IP.
Antibodies	PAS673Hu01	Polyclonal Antibody to Ephrin A2 (EFNA2)	WB; IHC; ICC; IF.
Assay Kits	CLS673Hu01	CLIA Kit for Ephrin A2 (EFNA2)	CLIA assay for Antigen Detection
Assay Kits	ELS673Hu01	ELISA Kit for Ephrin A2 (EFNA2)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPS673Mu01	Recombinant Ephrin A2 (EFNA2)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAS673Mu01	Monoclonal Antibody to Ephrin A2 (EFNA2)	WB; IHC; ICC; IP.
Antibodies	PAS673Mu01	Polyclonal Antibody to Ephrin A2 (EFNA2)	WB; IHC; ICC; IF.
Assay Kits	CLS673Mu01	CLIA Kit for Ephrin A2 (EFNA2)	CLIA assay for Antigen Detection
Assay Kits	ELS673Mu01	ELISA Kit for Ephrin A2 (EFNA2)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPS673Ra01	Recombinant Ephrin A2 (EFNA2)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAS673Ra01	Monoclonal Antibody to Ephrin A2 (EFNA2)	WB; IHC; ICC; IP.
Antibodies	PAS673Ra01	Polyclonal Antibody to Ephrin A2 (EFNA2)	WB; IHC; ICC; IF.
Assay Kits	CLS673Ra01	CLIA Kit for Ephrin A2 (EFNA2)	CLIA assay for Antigen Detection
Assay Kits	ELS673Ra01	ELISA Kit for Ephrin A2 (EFNA2)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPS673Ca01	Recombinant Ephrin A2 (EFNA2)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAS673Ca01	Monoclonal Antibody to Ephrin A2 (EFNA2)	WB; IHC; ICC; IP.
Antibodies	PAS673Ca01	Polyclonal Antibody to Ephrin A2 (EFNA2)	WB; IHC; ICC; IF.
Assay Kits	CLS673Ca01	CLIA Kit for Ephrin A2 (EFNA2)	CLIA assay for Antigen Detection
Assay Kits	ELS673Ca01	ELISA Kit for Ephrin A2 (EFNA2)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPS673Po01	Recombinant Ephrin A2 (EFNA2)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAS673Po01	Monoclonal Antibody to Ephrin A2 (EFNA2)	WB; IHC; ICC; IP.
Antibodies	PAS673Po01	Polyclonal Antibody to Ephrin A2 (EFNA2)	WB; IHC; ICC; IF.
Assay Kits	CLS673Po01	CLIA Kit for Ephrin A2 (EFNA2)	CLIA assay for Antigen Detection
Assay Kits	ELS673Po01	ELISA Kit for Ephrin A2 (EFNA2)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPS673Bo01	Recombinant Ephrin A2 (EFNA2)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAS673Bo01	Monoclonal Antibody to Ephrin A2 (EFNA2)	WB; IHC; ICC; IP.
Antibodies	PAS673Bo01	Polyclonal Antibody to Ephrin A2 (EFNA2)	WB; IHC; ICC; IF.
Assay Kits	CLS673Bo01	CLIA Kit for Ephrin A2 (EFNA2)	CLIA assay for Antigen Detection
Assay Kits	ELS673Bo01	ELISA Kit for Ephrin A2 (EFNA2)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPS673Rb01	Recombinant Ephrin A2 (EFNA2)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAS673Rb01	Monoclonal Antibody to Ephrin A2 (EFNA2)	WB; IHC; ICC; IP.
Antibodies	PAS673Rb01	Polyclonal Antibody to Ephrin A2 (EFNA2)	WB; IHC; ICC; IF.
Assay Kits	CLS673Rb01	CLIA Kit for Ephrin A2 (EFNA2)	CLIA assay for Antigen Detection
Assay Kits	ELS673Rb01	ELISA Kit for Ephrin A2 (EFNA2)	Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	RPS673Mo01	Recombinant Ephrin A2 (EFNA2)	Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies	MAS673Mo01	Monoclonal Antibody to Ephrin A2 (EFNA2)	WB; IHC; ICC; IP.
Antibodies	PAS673Mo01	Polyclonal Antibody to Ephrin A2 (EFNA2)	WB; IHC; ICC; IF.
Assay Kits	CLS673Mo01	CLIA Kit for Ephrin A2 (EFNA2)	CLIA assay for Antigen Detection
Assay Kits	ELS673Mo01	ELISA Kit for Ephrin A2 (EFNA2)	Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"Characterization of the genes for mouse LERK-3/Ephrin-A3 (Epl3), mouse LERK-4/Ephrin-A4 (Epl4), and human LERK-6/Ephrin-A2 (EPLG6): conservation of intron/exon structure."
Genomics 47:131-135(1998) [PubMed] [Europe PMC] [Abstract]

"Cloning, chromosomal mapping, and tissue expression of the gene encoding the human Eph-family kinase ligand ephrin-A2."
Biochem. Biophys. Res. Commun. 252:378-382(1998) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence and biology of human chromosome 19."
Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]

"Structural plasticity of EPH receptor A4 facilitates cross-class ephrin signaling."
Structure 17:1386-1397(2009) [PubMed] [Europe PMC] [Abstract]