Ephrin Type A Receptor 5 (EPHA5)
TYRO4; CEK7; EHK1; HEK7; Brain-specific kinase; EPH homology kinase 1; EPH-like kinase 7
EPH receptor A5 is a protein belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.Almost exclusively expressed in the nervous system.Unlike most other receptor PTKs, HEK7 has a restricted pattern of expression; Fox et al. (1995) observed 6-kb and 9-kb mRNAs in human brain and weak expression of the 9-kb mRNA in placenta.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS657Hu01 | Recombinant Ephrin Type A Receptor 5 (EPHA5) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS657Hu01 | Monoclonal Antibody to Ephrin Type A Receptor 5 (EPHA5) | WB; IHC; ICC; IP. |
| PAS657Hu01 | Polyclonal Antibody to Ephrin Type A Receptor 5 (EPHA5) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS657Hu01 | CLIA Kit for Ephrin Type A Receptor 5 (EPHA5) | CLIA assay for Antigen Detection |
| ELS657Hu01 | ELISA Kit for Ephrin Type A Receptor 5 (EPHA5) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS657Mu01 | Recombinant Ephrin Type A Receptor 5 (EPHA5) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS657Mu01 | Monoclonal Antibody to Ephrin Type A Receptor 5 (EPHA5) | WB; IHC; ICC; IP. |
| PAS657Mu01 | Polyclonal Antibody to Ephrin Type A Receptor 5 (EPHA5) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS657Mu01 | CLIA Kit for Ephrin Type A Receptor 5 (EPHA5) | CLIA assay for Antigen Detection |
| ELS657Mu01 | ELISA Kit for Ephrin Type A Receptor 5 (EPHA5) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS657Ra01 | Recombinant Ephrin Type A Receptor 5 (EPHA5) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS657Ra01 | Monoclonal Antibody to Ephrin Type A Receptor 5 (EPHA5) | WB; IHC; ICC; IP. |
| PAS657Ra01 | Polyclonal Antibody to Ephrin Type A Receptor 5 (EPHA5) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS657Ra01 | CLIA Kit for Ephrin Type A Receptor 5 (EPHA5) | CLIA assay for Antigen Detection |
| ELS657Ra01 | ELISA Kit for Ephrin Type A Receptor 5 (EPHA5) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS657Ca01 | Recombinant Ephrin Type A Receptor 5 (EPHA5) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS657Ca01 | Monoclonal Antibody to Ephrin Type A Receptor 5 (EPHA5) | WB; IHC; ICC; IP. |
| PAS657Ca01 | Polyclonal Antibody to Ephrin Type A Receptor 5 (EPHA5) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS657Ca01 | CLIA Kit for Ephrin Type A Receptor 5 (EPHA5) | CLIA assay for Antigen Detection |
| ELS657Ca01 | ELISA Kit for Ephrin Type A Receptor 5 (EPHA5) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS657Po01 | Recombinant Ephrin Type A Receptor 5 (EPHA5) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS657Po01 | Monoclonal Antibody to Ephrin Type A Receptor 5 (EPHA5) | WB; IHC; ICC; IP. |
| PAS657Po01 | Polyclonal Antibody to Ephrin Type A Receptor 5 (EPHA5) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS657Po01 | CLIA Kit for Ephrin Type A Receptor 5 (EPHA5) | CLIA assay for Antigen Detection |
| ELS657Po01 | ELISA Kit for Ephrin Type A Receptor 5 (EPHA5) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS657Bo01 | Recombinant Ephrin Type A Receptor 5 (EPHA5) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS657Bo01 | Monoclonal Antibody to Ephrin Type A Receptor 5 (EPHA5) | WB; IHC; ICC; IP. |
| PAS657Bo01 | Polyclonal Antibody to Ephrin Type A Receptor 5 (EPHA5) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS657Bo01 | CLIA Kit for Ephrin Type A Receptor 5 (EPHA5) | CLIA assay for Antigen Detection |
| ELS657Bo01 | ELISA Kit for Ephrin Type A Receptor 5 (EPHA5) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS657Rb01 | Recombinant Ephrin Type A Receptor 5 (EPHA5) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS657Rb01 | Monoclonal Antibody to Ephrin Type A Receptor 5 (EPHA5) | WB; IHC; ICC; IP. |
| PAS657Rb01 | Polyclonal Antibody to Ephrin Type A Receptor 5 (EPHA5) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS657Rb01 | CLIA Kit for Ephrin Type A Receptor 5 (EPHA5) | CLIA assay for Antigen Detection |
| ELS657Rb01 | ELISA Kit for Ephrin Type A Receptor 5 (EPHA5) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS657Mo01 | Recombinant Ephrin Type A Receptor 5 (EPHA5) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS657Mo01 | Monoclonal Antibody to Ephrin Type A Receptor 5 (EPHA5) | WB; IHC; ICC; IP. |
| PAS657Mo01 | Polyclonal Antibody to Ephrin Type A Receptor 5 (EPHA5) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS657Mo01 | CLIA Kit for Ephrin Type A Receptor 5 (EPHA5) | CLIA assay for Antigen Detection |
| ELS657Mo01 | ELISA Kit for Ephrin Type A Receptor 5 (EPHA5) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Extensive splice variation and localization of the EHK-1 receptor tyrosine kinase in adult human brain and glial tumors."
Brain Res. Mol. Brain Res. 46:17-24(1997) [PubMed] [Europe PMC] [Abstract]
"Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
"The full-ORF clone resource of the German cDNA consortium."
BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
"cDNA cloning and tissue distribution of five human EPH-like receptor protein-tyrosine kinases."
Oncogene 10:897-905(1995) [PubMed] [Europe PMC] [Abstract]
"Cloning of AL-1, a ligand for an Eph-related tyrosine kinase receptor involved in axon bundle formation."
Neuron 14:973-981(1995) [PubMed] [Europe PMC] [Abstract]
"Unified nomenclature for Eph family receptors and their ligands, the ephrins."
Cell 90:403-404(1997) [PubMed] [Europe PMC] [Abstract]
"Immunohistochemical localization of EphA5 in the adult human central nervous system."
J. Histochem. Cytochem. 47:855-861(1999) [PubMed] [Europe PMC] [Abstract]
"Patterns of somatic mutation in human cancer genomes."
Nature 446:153-158(2007) [PubMed] [Europe PMC] [Abstract]