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Defensin Beta 103A (DEFb103A)
Defensin Beta 103A (DEFb103A)
DEFB103; DEFB3; HBD-3; HBD3; HBP-3; HBP3; Beta-defensin 3; Defensin-like protein
Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. Beta-defensin 103 has broad spectrum antimicrobial activity and may play an important role in innate epithelial defense.Highly expressed in skin and tonsils, and to a lesser extent in trachea, uterus, kidney, thymus, adenoid, pharynx and tongue. Low expression in salivary gland, bone marrow, colon, stomach, polyp and larynx. No expression in small intestine.Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistent E.faecium. No significant hemolytic activity was observed.
Organism species: Homo sapiens (Human)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Defensin Beta 103A (DEFb103A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Defensin Beta 103A (DEFb103A) Bioactivity
Antibodies
MS651Hu21
Monoclonal Antibody to Defensin Beta 103A (DEFb103A) WB; IHC; ICC; IP.
PS651Hu01
Polyclonal Antibody to Defensin Beta 103A (DEFb103A) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) Flow Cytometry;ICC/IF
Assay Kits
KES651Hu
ELISA Kit for Defensin Beta 103A (DEFb103A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Defensin Beta 103A (DEFb103A) CLIA assay for Antigen Detection
Organism species: Mus musculus (Mouse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Defensin Beta 103A (DEFb103A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Defensin Beta 103A (DEFb103A) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Defensin Beta 103A (DEFb103A) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Defensin Beta 103A (DEFb103A) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Defensin Beta 103A (DEFb103A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Defensin Beta 103A (DEFb103A) CLIA assay for Antigen Detection
Organism species: Rattus norvegicus (Rat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Defensin Beta 103A (DEFb103A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Defensin Beta 103A (DEFb103A) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Defensin Beta 103A (DEFb103A) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Defensin Beta 103A (DEFb103A) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Defensin Beta 103A (DEFb103A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Defensin Beta 103A (DEFb103A) CLIA assay for Antigen Detection
Organism species: Canis familiaris; Canine (Dog)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Defensin Beta 103A (DEFb103A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Defensin Beta 103A (DEFb103A) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Defensin Beta 103A (DEFb103A) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Defensin Beta 103A (DEFb103A) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Defensin Beta 103A (DEFb103A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Defensin Beta 103A (DEFb103A) CLIA assay for Antigen Detection
Organism species: Sus scrofa; Porcine (Pig)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Defensin Beta 103A (DEFb103A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Defensin Beta 103A (DEFb103A) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Defensin Beta 103A (DEFb103A) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Defensin Beta 103A (DEFb103A) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Defensin Beta 103A (DEFb103A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Defensin Beta 103A (DEFb103A) CLIA assay for Antigen Detection
Organism species: Bos taurus; Bovine (Cattle)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Defensin Beta 103A (DEFb103A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Defensin Beta 103A (DEFb103A) Bioactivity
Antibodies
MS651Bo21
Monoclonal Antibody to Defensin Beta 103A (DEFb103A) WB; IHC; ICC; IP.
PS651Bo01
Polyclonal Antibody to Defensin Beta 103A (DEFb103A) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Defensin Beta 103A (DEFb103A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Defensin Beta 103A (DEFb103A) CLIA assay for Antigen Detection
Organism species: Rhesus monkey (Simian)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Defensin Beta 103A (DEFb103A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Defensin Beta 103A (DEFb103A) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Defensin Beta 103A (DEFb103A) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Defensin Beta 103A (DEFb103A) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Defensin Beta 103A (DEFb103A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Defensin Beta 103A (DEFb103A) CLIA assay for Antigen Detection
Organism species: Chicken (Gallus)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Defensin Beta 103A (DEFb103A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Defensin Beta 103A (DEFb103A) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Defensin Beta 103A (DEFb103A) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Defensin Beta 103A (DEFb103A) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Defensin Beta 103A (DEFb103A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Defensin Beta 103A (DEFb103A) CLIA assay for Antigen Detection
Organism species: Ovis aries; Ovine (Sheep)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Defensin Beta 103A (DEFb103A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Defensin Beta 103A (DEFb103A) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Defensin Beta 103A (DEFb103A) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Defensin Beta 103A (DEFb103A) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Defensin Beta 103A (DEFb103A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Defensin Beta 103A (DEFb103A) CLIA assay for Antigen Detection
Organism species: Oryctolagus cuniculus (Rabbit)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Defensin Beta 103A (DEFb103A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Defensin Beta 103A (DEFb103A) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Defensin Beta 103A (DEFb103A) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Defensin Beta 103A (DEFb103A) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Defensin Beta 103A (DEFb103A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Defensin Beta 103A (DEFb103A) CLIA assay for Antigen Detection
Organism species: Cavia (Guinea pig )
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Defensin Beta 103A (DEFb103A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Defensin Beta 103A (DEFb103A) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Defensin Beta 103A (DEFb103A) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Defensin Beta 103A (DEFb103A) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Defensin Beta 103A (DEFb103A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Defensin Beta 103A (DEFb103A) CLIA assay for Antigen Detection
Organism species: Equus caballus; Equine (Horse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Defensin Beta 103A (DEFb103A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Defensin Beta 103A (DEFb103A) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Defensin Beta 103A (DEFb103A) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Defensin Beta 103A (DEFb103A) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Defensin Beta 103A (DEFb103A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Defensin Beta 103A (DEFb103A) CLIA assay for Antigen Detection
Organism species: Capra hircus; Caprine (Goat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Defensin Beta 103A (DEFb103A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Defensin Beta 103A (DEFb103A) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Defensin Beta 103A (DEFb103A) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Defensin Beta 103A (DEFb103A) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Defensin Beta 103A (DEFb103A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Defensin Beta 103A (DEFb103A) CLIA assay for Antigen Detection
Organism species: Pan-species (General)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Defensin Beta 103A (DEFb103A) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Defensin Beta 103A (DEFb103A) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Defensin Beta 103A (DEFb103A) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Defensin Beta 103A (DEFb103A) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Defensin Beta 103A (DEFb103A) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Defensin Beta 103A (DEFb103A) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Defensin Beta 103A (DEFb103A) CLIA assay for Antigen Detection
Reference
"Isolation and characterization of human beta-defensin-3, a novel human inducible peptide antibiotic." J. Biol. Chem. 276:5707-5713(2001) [PubMed ] [Europe PMC ] [Abstract ]
"Identification of a novel, multifunctional beta-defensin (human beta-defensin 3) with specific antimicrobial activity. Its interaction with plasma membranes of Xenopus oocytes and the induction of macrophage chemoattraction." Cell Tissue Res. 306:257-264(2001) [PubMed ] [Europe PMC ] [Abstract ]
"Discovery of new human beta-defensins using a genomics-based approach." Gene 263:211-218(2001) [PubMed ] [Europe PMC ] [Abstract ]
"The solution structures of the human beta-defensins lead to a better understanding of the potent bactericidal activity of HBD3 against Staphylococcus aureus." J. Biol. Chem. 277:8279-8289(2002) [PubMed ] [Europe PMC ] [Abstract ]
