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Colipase, Pancreatic (CLPS)
Colipase, Pancreatic (CLPS)
Colipase,Pancreatic(CLPS) is a cofactor needed by pancreatic lipase for efficient dietary lipid hydrolysis. It binds to the C-terminal, non-catalytic domain of lipase, thereby stabilizing an active conformation and considerably increasing the overall hydrophobic binding site. The gene product allows lipase to anchor noncovalently to the surface of lipid micelles, counteracting the destabilizing influence of intestinal bile salts. This cofactor is only expressed in pancreatic acinar cells, suggesting regulation of expression by tissue-specific elements. Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase.
Organism species: Homo sapiens (Human)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Colipase, Pancreatic (CLPS) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Colipase, Pancreatic (CLPS) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Colipase, Pancreatic (CLPS) WB; IHC; ICC; IP.
PS608Hu01
Polyclonal Antibody to Colipase, Pancreatic (CLPS) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Colipase, Pancreatic (CLPS) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Colipase, Pancreatic (CLPS) CLIA assay for Antigen Detection
Organism species: Mus musculus (Mouse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Colipase, Pancreatic (CLPS) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Colipase, Pancreatic (CLPS) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Colipase, Pancreatic (CLPS) WB; IHC; ICC; IP.
PS608Mu01
Polyclonal Antibody to Colipase, Pancreatic (CLPS) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Colipase, Pancreatic (CLPS) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Colipase, Pancreatic (CLPS) CLIA assay for Antigen Detection
Organism species: Rattus norvegicus (Rat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Colipase, Pancreatic (CLPS) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Colipase, Pancreatic (CLPS) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Colipase, Pancreatic (CLPS) WB; IHC; ICC; IP.
PS608Ra01
Polyclonal Antibody to Colipase, Pancreatic (CLPS) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Colipase, Pancreatic (CLPS) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Colipase, Pancreatic (CLPS) CLIA assay for Antigen Detection
Organism species: Canis familiaris; Canine (Dog)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Colipase, Pancreatic (CLPS) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Colipase, Pancreatic (CLPS) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Colipase, Pancreatic (CLPS) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Colipase, Pancreatic (CLPS) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Colipase, Pancreatic (CLPS) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Colipase, Pancreatic (CLPS) CLIA assay for Antigen Detection
Organism species: Sus scrofa; Porcine (Pig)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Colipase, Pancreatic (CLPS) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Colipase, Pancreatic (CLPS) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Colipase, Pancreatic (CLPS) WB; IHC; ICC; IP.
PS608Po01
Polyclonal Antibody to Colipase, Pancreatic (CLPS) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) Flow Cytometry;ICC/IF
Assay Kits
KES608Po
ELISA Kit for Colipase, Pancreatic (CLPS) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Colipase, Pancreatic (CLPS) CLIA assay for Antigen Detection
Organism species: Bos taurus; Bovine (Cattle)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Colipase, Pancreatic (CLPS) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Colipase, Pancreatic (CLPS) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Colipase, Pancreatic (CLPS) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Colipase, Pancreatic (CLPS) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Colipase, Pancreatic (CLPS) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Colipase, Pancreatic (CLPS) CLIA assay for Antigen Detection
Organism species: Rhesus monkey (Simian)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Colipase, Pancreatic (CLPS) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Colipase, Pancreatic (CLPS) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Colipase, Pancreatic (CLPS) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Colipase, Pancreatic (CLPS) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Colipase, Pancreatic (CLPS) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Colipase, Pancreatic (CLPS) CLIA assay for Antigen Detection
Organism species: Chicken (Gallus)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Colipase, Pancreatic (CLPS) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Colipase, Pancreatic (CLPS) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Colipase, Pancreatic (CLPS) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Colipase, Pancreatic (CLPS) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Colipase, Pancreatic (CLPS) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Colipase, Pancreatic (CLPS) CLIA assay for Antigen Detection
Organism species: Ovis aries; Ovine (Sheep)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Colipase, Pancreatic (CLPS) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Colipase, Pancreatic (CLPS) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Colipase, Pancreatic (CLPS) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Colipase, Pancreatic (CLPS) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Colipase, Pancreatic (CLPS) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Colipase, Pancreatic (CLPS) CLIA assay for Antigen Detection
Organism species: Oryctolagus cuniculus (Rabbit)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Colipase, Pancreatic (CLPS) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Colipase, Pancreatic (CLPS) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Colipase, Pancreatic (CLPS) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Colipase, Pancreatic (CLPS) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Colipase, Pancreatic (CLPS) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Colipase, Pancreatic (CLPS) CLIA assay for Antigen Detection
Organism species: Cavia (Guinea pig )
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Colipase, Pancreatic (CLPS) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Colipase, Pancreatic (CLPS) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Colipase, Pancreatic (CLPS) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Colipase, Pancreatic (CLPS) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Colipase, Pancreatic (CLPS) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Colipase, Pancreatic (CLPS) CLIA assay for Antigen Detection
Organism species: Equus caballus; Equine (Horse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Colipase, Pancreatic (CLPS) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Colipase, Pancreatic (CLPS) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Colipase, Pancreatic (CLPS) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Colipase, Pancreatic (CLPS) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Colipase, Pancreatic (CLPS) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Colipase, Pancreatic (CLPS) CLIA assay for Antigen Detection
Organism species: Capra hircus; Caprine (Goat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Colipase, Pancreatic (CLPS) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Colipase, Pancreatic (CLPS) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Colipase, Pancreatic (CLPS) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Colipase, Pancreatic (CLPS) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Colipase, Pancreatic (CLPS) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Colipase, Pancreatic (CLPS) CLIA assay for Antigen Detection
Organism species: Pan-species (General)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Colipase, Pancreatic (CLPS) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Colipase, Pancreatic (CLPS) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Colipase, Pancreatic (CLPS) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Colipase, Pancreatic (CLPS) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Colipase, Pancreatic (CLPS) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Colipase, Pancreatic (CLPS) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Colipase, Pancreatic (CLPS) CLIA assay for Antigen Detection
Reference
"Cloning and characterization of the human colipase cDNA." Biochemistry 29:823-828(1990) [PubMed ] [Europe PMC ] [Abstract ]
"The human colipase gene: isolation, chromosomal location, and tissue-specific expression." Biochemistry 31:7120-7125(1992) [PubMed ] [Europe PMC ] [Abstract ]
"The DNA sequence and analysis of human chromosome 6." Nature 425:805-811(2003) [PubMed ] [Europe PMC ] [Abstract ]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." Genome Res. 14:2121-2127(2004) [PubMed ] [Europe PMC ] [Abstract ]
"The primary sequence of human pancreatic colipase." Biochim. Biophys. Acta 784:75-80(1984) [PubMed ] [Europe PMC ] [Abstract ]
"Interfacial activation of the lipase-procolipase complex by mixed micelles revealed by X-ray crystallography." Nature 362:814-820(1993) [PubMed ] [Europe PMC ] [Abstract ]
"Putative association between a new polymorphism in exon 3 (Arg109Cys) of the pancreatic colipase gene and type 2 diabetes mellitus in two independent Caucasian study populations." Mol. Nutr. Food Res. 49:972-976(2005) [PubMed ] [Europe PMC ] [Abstract ]
