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Ras Homolog Gene Family, Member Q (RHOQ)

ARHQ; RASL7A; TC10; TC10A; Ras-like protein family member 7A

TC10 is a member of the RAS superfamily of small GTP-binding proteins involved in insulin-stimulated glucose uptake.TC10 is a member of the Rho group of RAS-related genes, encoding proteins thought to play a role in the control of microfilament assembly. TC10 exhibits approximately 60% nucleotide sequence homology to TC25 and to other RHO genes. Drivas et al. (1990) detected TC10 expression in human 293 cells and mouse NIH 3T3 cells, but not in HeLa or Jurkat T-cell lines.The stimulation of glucose uptake by insulin in muscle and adipose tissue requires translocation of the GLUT4 glucose transporter from intracellular storage sites to the cell surface. Activation of phosphatidylinositol-3-OH kinase (PI3K) is required for this trafficking event, but it is not sufficient to produce GLUT4 translocation

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPS456Hu01 Recombinant Ras Homolog Gene Family, Member Q (RHOQ) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAS456Hu01 Monoclonal Antibody to Ras Homolog Gene Family, Member Q (RHOQ) WB; IHC; ICC; IP.
PAS456Hu01 Polyclonal Antibody to Ras Homolog Gene Family, Member Q (RHOQ) WB; IHC; ICC; IF.
Assay Kits CLS456Hu01 CLIA Kit for Ras Homolog Gene Family, Member Q (RHOQ) CLIA assay for Antigen Detection
ELS456Hu01 ELISA Kit for Ras Homolog Gene Family, Member Q (RHOQ) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPS456Mu01 Recombinant Ras Homolog Gene Family, Member Q (RHOQ) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAS456Mu01 Monoclonal Antibody to Ras Homolog Gene Family, Member Q (RHOQ) WB; IHC; ICC; IP.
PAS456Mu01 Polyclonal Antibody to Ras Homolog Gene Family, Member Q (RHOQ) WB; IHC; ICC; IF.
Assay Kits CLS456Mu01 CLIA Kit for Ras Homolog Gene Family, Member Q (RHOQ) CLIA assay for Antigen Detection
ELS456Mu01 ELISA Kit for Ras Homolog Gene Family, Member Q (RHOQ) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPS456Ra01 Recombinant Ras Homolog Gene Family, Member Q (RHOQ) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAS456Ra01 Monoclonal Antibody to Ras Homolog Gene Family, Member Q (RHOQ) WB; IHC; ICC; IP.
PAS456Ra01 Polyclonal Antibody to Ras Homolog Gene Family, Member Q (RHOQ) WB; IHC; ICC; IF.
Assay Kits CLS456Ra01 CLIA Kit for Ras Homolog Gene Family, Member Q (RHOQ) CLIA assay for Antigen Detection
ELS456Ra01 ELISA Kit for Ras Homolog Gene Family, Member Q (RHOQ) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPS456Ca01 Recombinant Ras Homolog Gene Family, Member Q (RHOQ) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAS456Ca01 Monoclonal Antibody to Ras Homolog Gene Family, Member Q (RHOQ) WB; IHC; ICC; IP.
PAS456Ca01 Polyclonal Antibody to Ras Homolog Gene Family, Member Q (RHOQ) WB; IHC; ICC; IF.
Assay Kits CLS456Ca01 CLIA Kit for Ras Homolog Gene Family, Member Q (RHOQ) CLIA assay for Antigen Detection
ELS456Ca01 ELISA Kit for Ras Homolog Gene Family, Member Q (RHOQ) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPS456Po01 Recombinant Ras Homolog Gene Family, Member Q (RHOQ) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAS456Po01 Monoclonal Antibody to Ras Homolog Gene Family, Member Q (RHOQ) WB; IHC; ICC; IP.
PAS456Po01 Polyclonal Antibody to Ras Homolog Gene Family, Member Q (RHOQ) WB; IHC; ICC; IF.
Assay Kits CLS456Po01 CLIA Kit for Ras Homolog Gene Family, Member Q (RHOQ) CLIA assay for Antigen Detection
ELS456Po01 ELISA Kit for Ras Homolog Gene Family, Member Q (RHOQ) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPS456Bo01 Recombinant Ras Homolog Gene Family, Member Q (RHOQ) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAS456Bo01 Monoclonal Antibody to Ras Homolog Gene Family, Member Q (RHOQ) WB; IHC; ICC; IP.
PAS456Bo01 Polyclonal Antibody to Ras Homolog Gene Family, Member Q (RHOQ) WB; IHC; ICC; IF.
Assay Kits CLS456Bo01 CLIA Kit for Ras Homolog Gene Family, Member Q (RHOQ) CLIA assay for Antigen Detection
ELS456Bo01 ELISA Kit for Ras Homolog Gene Family, Member Q (RHOQ) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPS456Rb01 Recombinant Ras Homolog Gene Family, Member Q (RHOQ) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAS456Rb01 Monoclonal Antibody to Ras Homolog Gene Family, Member Q (RHOQ) WB; IHC; ICC; IP.
PAS456Rb01 Polyclonal Antibody to Ras Homolog Gene Family, Member Q (RHOQ) WB; IHC; ICC; IF.
Assay Kits CLS456Rb01 CLIA Kit for Ras Homolog Gene Family, Member Q (RHOQ) CLIA assay for Antigen Detection
ELS456Rb01 ELISA Kit for Ras Homolog Gene Family, Member Q (RHOQ) Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPS456Mo01 Recombinant Ras Homolog Gene Family, Member Q (RHOQ) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAS456Mo01 Monoclonal Antibody to Ras Homolog Gene Family, Member Q (RHOQ) WB; IHC; ICC; IP.
PAS456Mo01 Polyclonal Antibody to Ras Homolog Gene Family, Member Q (RHOQ) WB; IHC; ICC; IF.
Assay Kits CLS456Mo01 CLIA Kit for Ras Homolog Gene Family, Member Q (RHOQ) CLIA assay for Antigen Detection
ELS456Mo01 ELISA Kit for Ras Homolog Gene Family, Member Q (RHOQ) Enzyme-linked immunosorbent assay for Antigen Detection

Reference

"Characterization of four novel ras-like genes expressed in a human teratocarcinoma cell line."
Mol. Cell. Biol. 10:1793-1798(1990) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence and analysis of human chromosome 14."
Nature 421:601-607(2003) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"The Borgs, a new family of Cdc42 and TC10 GTPase-interacting proteins."
Mol. Cell. Biol. 19:6585-6597(1999) [PubMed] [Europe PMC] [Abstract]

"The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42."
Nat. Cell Biol. 2:531-539(2000) [PubMed] [Europe PMC] [Abstract]

"PIST: a novel PDZ/coiled-coil domain binding partner for the rho-family GTPase TC10."
Biochem. Biophys. Res. Commun. 280:541-547(2001) [PubMed] [Europe PMC] [Abstract]

"Regulation of cystic fibrosis transmembrane regulator trafficking and protein expression by a Rho family small GTPase TC10."
J. Biol. Chem. 280:3731-3739(2005) [PubMed] [Europe PMC] [Abstract]