Na-Cl Cotransporter (NCCT)
SLC12A3; TSC; NCC; Solute Carrier Family 12 Member 3,Sodium/Chloride Transporters; Thiazide-sensitive sodium-chloride cotransporter; Na-Cl symporter
SLC12A3 encodes a renal thiazide-sensitive sodium-chloride cotransporter that is important for electrolyte homeostasis. This cotransporter mediates sodium and chloride reabsorption in the distal convoluted tubule. Mutations in this gene cause Gitelman syndrome, a disease similar to Bartter's syndrome, that is characterized by hypokalemic alkalosis combined with hypomagnesemia, low urinary calcium, and increased renin activity associated with normal blood pressure. This cotransporter is the target for thiazide diuretics that are used for treating high blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene. The predicted protein sequence of 1,021 amino acids (112 kD) showed a structure common to other members of the Na-K-Cl cotransporter family.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | S429Hu01 | Recombinant Na-Cl Cotransporter (NCCT) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Na-Cl Cotransporter (NCCT) | Bioactivity | |
| Antibodies | MS429Hu21 | Monoclonal Antibody to Na-Cl Cotransporter (NCCT) | WB; IHC; ICC; IP. |
| PS429Hu01 | Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | WB; IHC; ICC; IF. | |
| LS429Hu71 | Biotin Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | Flow Cytometry;ICC/IF | |
| Assay Kits | KES429Hu | ELISA Kit for Na-Cl Cotransporter (NCCT) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Na-Cl Cotransporter (NCCT) | CLIA assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Na-Cl Cotransporter (NCCT) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Na-Cl Cotransporter (NCCT) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Na-Cl Cotransporter (NCCT) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Na-Cl Cotransporter (NCCT) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Na-Cl Cotransporter (NCCT) | CLIA assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Na-Cl Cotransporter (NCCT) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Na-Cl Cotransporter (NCCT) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Na-Cl Cotransporter (NCCT) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Na-Cl Cotransporter (NCCT) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Na-Cl Cotransporter (NCCT) | CLIA assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Na-Cl Cotransporter (NCCT) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Na-Cl Cotransporter (NCCT) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Na-Cl Cotransporter (NCCT) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Na-Cl Cotransporter (NCCT) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Na-Cl Cotransporter (NCCT) | CLIA assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Na-Cl Cotransporter (NCCT) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Na-Cl Cotransporter (NCCT) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Na-Cl Cotransporter (NCCT) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Na-Cl Cotransporter (NCCT) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Na-Cl Cotransporter (NCCT) | CLIA assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Na-Cl Cotransporter (NCCT) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Na-Cl Cotransporter (NCCT) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Na-Cl Cotransporter (NCCT) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Na-Cl Cotransporter (NCCT) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Na-Cl Cotransporter (NCCT) | CLIA assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Na-Cl Cotransporter (NCCT) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Na-Cl Cotransporter (NCCT) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Na-Cl Cotransporter (NCCT) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Na-Cl Cotransporter (NCCT) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Na-Cl Cotransporter (NCCT) | CLIA assay for Antigen Detection |
Organism species: Chicken (Gallus)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Na-Cl Cotransporter (NCCT) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Na-Cl Cotransporter (NCCT) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Na-Cl Cotransporter (NCCT) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Na-Cl Cotransporter (NCCT) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Na-Cl Cotransporter (NCCT) | CLIA assay for Antigen Detection |
Organism species: Ovis aries; Ovine (Sheep)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Na-Cl Cotransporter (NCCT) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Na-Cl Cotransporter (NCCT) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Na-Cl Cotransporter (NCCT) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Na-Cl Cotransporter (NCCT) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Na-Cl Cotransporter (NCCT) | CLIA assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Na-Cl Cotransporter (NCCT) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Na-Cl Cotransporter (NCCT) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Na-Cl Cotransporter (NCCT) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Na-Cl Cotransporter (NCCT) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Na-Cl Cotransporter (NCCT) | CLIA assay for Antigen Detection |
Organism species: Cavia (Guinea pig )
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Na-Cl Cotransporter (NCCT) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Na-Cl Cotransporter (NCCT) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Na-Cl Cotransporter (NCCT) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Na-Cl Cotransporter (NCCT) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Na-Cl Cotransporter (NCCT) | CLIA assay for Antigen Detection |
Organism species: Equus caballus; Equine (Horse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Na-Cl Cotransporter (NCCT) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Na-Cl Cotransporter (NCCT) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Na-Cl Cotransporter (NCCT) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Na-Cl Cotransporter (NCCT) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Na-Cl Cotransporter (NCCT) | CLIA assay for Antigen Detection |
Organism species: Capra hircus; Caprine (Goat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Na-Cl Cotransporter (NCCT) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Na-Cl Cotransporter (NCCT) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Na-Cl Cotransporter (NCCT) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Na-Cl Cotransporter (NCCT) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Na-Cl Cotransporter (NCCT) | CLIA assay for Antigen Detection |
Organism species: Pan-species (General)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | NONE | Recombinant Na-Cl Cotransporter (NCCT) | Positive Control; Immunogen; SDS-PAGE; WB. |
| NONE | Native Na-Cl Cotransporter (NCCT) | Bioactivity | |
| Antibodies | NONE | Monoclonal Antibody to Na-Cl Cotransporter (NCCT) | WB; IHC; ICC; IP. |
| NONE | Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | WB; IHC; ICC; IF. | |
| NONE | Biotin Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | ELISA(Det);IC; IH; IH(P); WB | |
| NONE | APC Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | IHC, WB | |
| NONE | HRP Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | Simple Western; WB | |
| NONE | PE Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | Flow Cytometry | |
| NONE | FITC Linked-Polyclonal Antibody to Na-Cl Cotransporter (NCCT) | Flow Cytometry;ICC/IF | |
| Assay Kits | NONE | ELISA Kit for Na-Cl Cotransporter (NCCT) | Enzyme-linked immunosorbent assay for Antigen Detection |
| NONE | CLIA kit for Na-Cl Cotransporter (NCCT) | CLIA assay for Antigen Detection |
Reference
"Gitelman's variant of Bartter's syndrome, inherited hypokalaemic alkalosis, is caused by mutations in the thiazide-sensitive Na-Cl cotransporter."
Nat. Genet. 12:24-30(1996) [PubMed] [Europe PMC] [Abstract]
"Molecular cloning, expression pattern, and chromosomal localization of the human Na-Cl thiazide-sensitive cotransporter (SLC12A3)."
Genomics 35:486-493(1996) [PubMed] [Europe PMC] [Abstract]
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
"The sequence and analysis of duplication-rich human chromosome 16."
Nature 432:988-994(2004) [PubMed] [Europe PMC] [Abstract]
"Similar Effects of all WNK3 Variants upon SLC12 Cotransporters."
Am. J. Physiol. 301:C601-C608(2011) [PubMed] [Europe PMC] [Abstract]
"Novel molecular variants of the Na-Cl cotransporter gene are responsible for Gitelman syndrome."
Am. J. Hum. Genet. 59:1019-1026(1996) [PubMed] [Europe PMC] [Abstract]
"KLHL3 mutations cause familial hyperkalemic hypertension by impairing ion transport in the distal nephron."
Nat. Genet. 44:456-460(2012) [PubMed] [Europe PMC] [Abstract]
"Association of a mutation in thiazide-sensitive Na-Cl cotransporter with familial Gitelman's syndrome."
J. Clin. Endocrinol. Metab. 81:4496-4499(1996) [PubMed] [Europe PMC] [Abstract]
"Novel mutations in the thiazide-sensitive NaCl cotransporter gene in patients with Gitelman syndrome with predominant localization to the C-terminal domain."
Kidney Int. 54:720-730(1998) [PubMed] [Europe PMC] [Abstract]
"Genetic variants of thiazide-sensitive NaCl-cotransporter in Gitelman's syndrome and primary hypertension."
Hypertension 36:389-394(2000) [PubMed] [Europe PMC] [Abstract]
"Novel mutations in thiazide-sensitive Na-Cl cotransporter gene of patients with Gitelman's syndrome."
J. Am. Soc. Nephrol. 11:65-70(2000) [PubMed] [Europe PMC] [Abstract]
"Gitelman's syndrome revisited: an evaluation of symptoms and health-related quality of life."
Kidney Int. 59:710-717(2001) [PubMed] [Europe PMC] [Abstract]
"Severe hypomagnesaemia-induced hypocalcaemia in a patient with Gitelman's syndrome."
Clin. Endocrinol. (Oxf.) 56:413-418(2002) [PubMed] [Europe PMC] [Abstract]
"Two novel mutations of thiazide-sensitive Na-Cl cotrans porter (TSC) gene in two sporadic Japanese patients with Gitelman syndrome."
Endocr. J. 49:91-96(2002) [PubMed] [Europe PMC] [Abstract]
"Identification of fifteen novel mutations in the SLC12A3 gene encoding the Na-Cl Co-transporter in Italian patients with Gitelman syndrome."
Hum. Mutat. 20:78-78(2002) [PubMed] [Europe PMC] [Abstract]
"Four novel mutations in the thiazide-sensitive Na-Cl co-transporter gene in Japanese patients with Gitelman's syndrome."
Nephrol. Dial. Transplant. 19:1761-1766(2004) [PubMed] [Europe PMC] [Abstract]
"Phenotype and genotype analysis in Chinese patients with Gitelman's syndrome."
J. Clin. Endocrinol. Metab. 90:2500-2507(2005) [PubMed] [Europe PMC] [Abstract]
"A novel mutation of the thiazide-sensitive sodium chloride cotransporter gene in a Japanese family with Gitelman syndrome."
Clin. Nephrol. 65:57-60(2006) [PubMed] [Europe PMC] [Abstract]
"Novel mutations in the SLC12A3 gene causing Gitelman's syndrome in Swedes."
DNA Seq. 18:395-399(2007) [PubMed] [Europe PMC] [Abstract]
"Two novel genotypes of the thiazide-sensitive Na-Cl cotransporter (SLC12A3) gene in patients with Gitelman's syndrome."
Endocrine 31:149-153(2007) [PubMed] [Europe PMC] [Abstract]
"Molecular variants of the thiazide-sensitive Na+-Cl- cotransporter in hypertensive families."
J. Hypertens. 25:2074-2081(2007) [PubMed] [Europe PMC] [Abstract]