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High Affinity Choline Transporter (ChT)
High Affinity Choline Transporter (ChT)
SLC5A7; hCHT, CHT1; Solute Carrier Family 5 Member 7,Choline Transporter; Hemicholinium-3-sensitive choline transporter
Choline is a direct precursor of acetylcholine (ACh), a neurotransmitter of the central and peripheral nervous system that regulates a variety of autonomic, cognitive, and motor functions. SLC5A7 is a Na(+)- and Cl(-)- dependent high-affinity transporter that mediates the uptake of choline for acetylcholine synthesis in cholinergic neurons.The deduced 580-amino acid protein has a calculated molecular mass of 63.2 kD.
CHT has 13 transmembrane (TM) domains, a short extracellular N terminus, and a long cytoplasmic C terminus. It contains 3 putative N-glycosylation sites and several phosphorylation sites. CHT shares 93% amino acid identity with rat Cht and 51% amino acid identity with its nematode homolog, Cho1.
Organism species: Homo sapiens (Human)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant High Affinity Choline Transporter (ChT) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native High Affinity Choline Transporter (ChT) Bioactivity
Antibodies
NONE
Monoclonal Antibody to High Affinity Choline Transporter (ChT) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to High Affinity Choline Transporter (ChT) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for High Affinity Choline Transporter (ChT) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for High Affinity Choline Transporter (ChT) CLIA assay for Antigen Detection
Organism species: Mus musculus (Mouse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant High Affinity Choline Transporter (ChT) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native High Affinity Choline Transporter (ChT) Bioactivity
Antibodies
NONE
Monoclonal Antibody to High Affinity Choline Transporter (ChT) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to High Affinity Choline Transporter (ChT) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for High Affinity Choline Transporter (ChT) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for High Affinity Choline Transporter (ChT) CLIA assay for Antigen Detection
Organism species: Rattus norvegicus (Rat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant High Affinity Choline Transporter (ChT) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native High Affinity Choline Transporter (ChT) Bioactivity
Antibodies
MS410Ra21
Monoclonal Antibody to High Affinity Choline Transporter (ChT) WB; IHC; ICC; IP.
PS410Ra01
Polyclonal Antibody to High Affinity Choline Transporter (ChT) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) Flow Cytometry;ICC/IF
Assay Kits
KES410Ra
ELISA Kit for High Affinity Choline Transporter (ChT) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for High Affinity Choline Transporter (ChT) CLIA assay for Antigen Detection
Organism species: Canis familiaris; Canine (Dog)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant High Affinity Choline Transporter (ChT) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native High Affinity Choline Transporter (ChT) Bioactivity
Antibodies
NONE
Monoclonal Antibody to High Affinity Choline Transporter (ChT) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to High Affinity Choline Transporter (ChT) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for High Affinity Choline Transporter (ChT) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for High Affinity Choline Transporter (ChT) CLIA assay for Antigen Detection
Organism species: Sus scrofa; Porcine (Pig)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant High Affinity Choline Transporter (ChT) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native High Affinity Choline Transporter (ChT) Bioactivity
Antibodies
NONE
Monoclonal Antibody to High Affinity Choline Transporter (ChT) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to High Affinity Choline Transporter (ChT) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for High Affinity Choline Transporter (ChT) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for High Affinity Choline Transporter (ChT) CLIA assay for Antigen Detection
Organism species: Bos taurus; Bovine (Cattle)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant High Affinity Choline Transporter (ChT) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native High Affinity Choline Transporter (ChT) Bioactivity
Antibodies
NONE
Monoclonal Antibody to High Affinity Choline Transporter (ChT) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to High Affinity Choline Transporter (ChT) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for High Affinity Choline Transporter (ChT) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for High Affinity Choline Transporter (ChT) CLIA assay for Antigen Detection
Organism species: Rhesus monkey (Simian)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant High Affinity Choline Transporter (ChT) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native High Affinity Choline Transporter (ChT) Bioactivity
Antibodies
NONE
Monoclonal Antibody to High Affinity Choline Transporter (ChT) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to High Affinity Choline Transporter (ChT) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for High Affinity Choline Transporter (ChT) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for High Affinity Choline Transporter (ChT) CLIA assay for Antigen Detection
Organism species: Chicken (Gallus)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant High Affinity Choline Transporter (ChT) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native High Affinity Choline Transporter (ChT) Bioactivity
Antibodies
NONE
Monoclonal Antibody to High Affinity Choline Transporter (ChT) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to High Affinity Choline Transporter (ChT) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for High Affinity Choline Transporter (ChT) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for High Affinity Choline Transporter (ChT) CLIA assay for Antigen Detection
Organism species: Ovis aries; Ovine (Sheep)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant High Affinity Choline Transporter (ChT) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native High Affinity Choline Transporter (ChT) Bioactivity
Antibodies
NONE
Monoclonal Antibody to High Affinity Choline Transporter (ChT) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to High Affinity Choline Transporter (ChT) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for High Affinity Choline Transporter (ChT) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for High Affinity Choline Transporter (ChT) CLIA assay for Antigen Detection
Organism species: Oryctolagus cuniculus (Rabbit)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant High Affinity Choline Transporter (ChT) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native High Affinity Choline Transporter (ChT) Bioactivity
Antibodies
NONE
Monoclonal Antibody to High Affinity Choline Transporter (ChT) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to High Affinity Choline Transporter (ChT) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for High Affinity Choline Transporter (ChT) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for High Affinity Choline Transporter (ChT) CLIA assay for Antigen Detection
Organism species: Cavia (Guinea pig )
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant High Affinity Choline Transporter (ChT) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native High Affinity Choline Transporter (ChT) Bioactivity
Antibodies
NONE
Monoclonal Antibody to High Affinity Choline Transporter (ChT) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to High Affinity Choline Transporter (ChT) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for High Affinity Choline Transporter (ChT) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for High Affinity Choline Transporter (ChT) CLIA assay for Antigen Detection
Organism species: Equus caballus; Equine (Horse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant High Affinity Choline Transporter (ChT) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native High Affinity Choline Transporter (ChT) Bioactivity
Antibodies
NONE
Monoclonal Antibody to High Affinity Choline Transporter (ChT) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to High Affinity Choline Transporter (ChT) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for High Affinity Choline Transporter (ChT) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for High Affinity Choline Transporter (ChT) CLIA assay for Antigen Detection
Organism species: Capra hircus; Caprine (Goat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant High Affinity Choline Transporter (ChT) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native High Affinity Choline Transporter (ChT) Bioactivity
Antibodies
NONE
Monoclonal Antibody to High Affinity Choline Transporter (ChT) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to High Affinity Choline Transporter (ChT) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for High Affinity Choline Transporter (ChT) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for High Affinity Choline Transporter (ChT) CLIA assay for Antigen Detection
Organism species: Pan-species (General)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant High Affinity Choline Transporter (ChT) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native High Affinity Choline Transporter (ChT) Bioactivity
Antibodies
NONE
Monoclonal Antibody to High Affinity Choline Transporter (ChT) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to High Affinity Choline Transporter (ChT) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to High Affinity Choline Transporter (ChT) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for High Affinity Choline Transporter (ChT) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for High Affinity Choline Transporter (ChT) CLIA assay for Antigen Detection
Reference
"Molecular cloning of a human, hemicholinium-3-sensitive choline transporter." Biochem. Biophys. Res. Commun. 276:862-867(2000) [PubMed ] [Europe PMC ] [Abstract ]
"Functional characterization of the human high-affinity choline transporter." FEBS Lett. 484:92-97(2000) [PubMed ] [Europe PMC ] [Abstract ]
"Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed ] [Europe PMC ] [Abstract ]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." Genome Res. 14:2121-2127(2004) [PubMed ] [Europe PMC ] [Abstract ]
"Defective presynaptic choline transport underlies hereditary motor neuropathy." Am. J. Hum. Genet. 91:1103-1107(2012) [PubMed ] [Europe PMC ] [Abstract ]
"Transmembrane topology and oligomeric structure of the high-affinity choline transporter." J. Biol. Chem. 287:42826-42834(2012) [PubMed ] [Europe PMC ] [Abstract ]
"Single nucleotide polymorphism of the human high affinity choline transporter alters transport rate." J. Biol. Chem. 277:45315-45322(2002) [PubMed ] [Europe PMC ] [Abstract ]
