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Testis Anion Transporter 1 (TAT1)

SLC26A8; Solute Carrier Family 26 Member 8; Anion exchange transporter

SLC26A8 is one member of a family of sulfate/anion transporter genes. Family members are well conserved in their genomic (number and size of exons) and protein (aa length among species) structures yet have markedly different tissue expression patterns. This gene is expressed primarily in spermatocytes. Two transcript variants encoding different isoforms have been found. The deduced 970-amino acid protein has a calculated molecular mass of 109 kD. SLC26A8 contains 14 putative transmembrane regions with cytoplasmic N- and C-termini. It also contains several N-glycosylation sites, 4 of which reside in the major predicted external loop. SLC26A8 shares 26% identity with pendrin (SLC26A4), and 28% identity with DRA (SLC26A3).

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Testis Anion Transporter 1 (TAT1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Testis Anion Transporter 1 (TAT1) Bioactivity
Antibodies MS323Hu21 Monoclonal Antibody to Testis Anion Transporter 1 (TAT1) WB; IHC; ICC; IP.
PS323Hu01 Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) Flow Cytometry;ICC/IF
Assay Kits KES323Hu ELISA Kit for Testis Anion Transporter 1 (TAT1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Testis Anion Transporter 1 (TAT1) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Testis Anion Transporter 1 (TAT1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Testis Anion Transporter 1 (TAT1) Bioactivity
Antibodies NONE Monoclonal Antibody to Testis Anion Transporter 1 (TAT1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Testis Anion Transporter 1 (TAT1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Testis Anion Transporter 1 (TAT1) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Testis Anion Transporter 1 (TAT1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Testis Anion Transporter 1 (TAT1) Bioactivity
Antibodies NONE Monoclonal Antibody to Testis Anion Transporter 1 (TAT1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Testis Anion Transporter 1 (TAT1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Testis Anion Transporter 1 (TAT1) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Testis Anion Transporter 1 (TAT1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Testis Anion Transporter 1 (TAT1) Bioactivity
Antibodies NONE Monoclonal Antibody to Testis Anion Transporter 1 (TAT1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Testis Anion Transporter 1 (TAT1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Testis Anion Transporter 1 (TAT1) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Testis Anion Transporter 1 (TAT1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Testis Anion Transporter 1 (TAT1) Bioactivity
Antibodies NONE Monoclonal Antibody to Testis Anion Transporter 1 (TAT1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Testis Anion Transporter 1 (TAT1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Testis Anion Transporter 1 (TAT1) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Testis Anion Transporter 1 (TAT1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Testis Anion Transporter 1 (TAT1) Bioactivity
Antibodies NONE Monoclonal Antibody to Testis Anion Transporter 1 (TAT1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Testis Anion Transporter 1 (TAT1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Testis Anion Transporter 1 (TAT1) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Testis Anion Transporter 1 (TAT1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Testis Anion Transporter 1 (TAT1) Bioactivity
Antibodies NONE Monoclonal Antibody to Testis Anion Transporter 1 (TAT1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Testis Anion Transporter 1 (TAT1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Testis Anion Transporter 1 (TAT1) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Testis Anion Transporter 1 (TAT1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Testis Anion Transporter 1 (TAT1) Bioactivity
Antibodies NONE Monoclonal Antibody to Testis Anion Transporter 1 (TAT1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Testis Anion Transporter 1 (TAT1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Testis Anion Transporter 1 (TAT1) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Testis Anion Transporter 1 (TAT1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Testis Anion Transporter 1 (TAT1) Bioactivity
Antibodies NONE Monoclonal Antibody to Testis Anion Transporter 1 (TAT1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Testis Anion Transporter 1 (TAT1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Testis Anion Transporter 1 (TAT1) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Testis Anion Transporter 1 (TAT1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Testis Anion Transporter 1 (TAT1) Bioactivity
Antibodies NONE Monoclonal Antibody to Testis Anion Transporter 1 (TAT1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Testis Anion Transporter 1 (TAT1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Testis Anion Transporter 1 (TAT1) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Testis Anion Transporter 1 (TAT1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Testis Anion Transporter 1 (TAT1) Bioactivity
Antibodies NONE Monoclonal Antibody to Testis Anion Transporter 1 (TAT1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Testis Anion Transporter 1 (TAT1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Testis Anion Transporter 1 (TAT1) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Testis Anion Transporter 1 (TAT1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Testis Anion Transporter 1 (TAT1) Bioactivity
Antibodies NONE Monoclonal Antibody to Testis Anion Transporter 1 (TAT1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Testis Anion Transporter 1 (TAT1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Testis Anion Transporter 1 (TAT1) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Testis Anion Transporter 1 (TAT1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Testis Anion Transporter 1 (TAT1) Bioactivity
Antibodies NONE Monoclonal Antibody to Testis Anion Transporter 1 (TAT1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Testis Anion Transporter 1 (TAT1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Testis Anion Transporter 1 (TAT1) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Testis Anion Transporter 1 (TAT1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Testis Anion Transporter 1 (TAT1) Bioactivity
Antibodies NONE Monoclonal Antibody to Testis Anion Transporter 1 (TAT1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Testis Anion Transporter 1 (TAT1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Testis Anion Transporter 1 (TAT1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Testis Anion Transporter 1 (TAT1) CLIA assay for Antigen Detection

Reference

"Tat1, a novel sulfate transporter specifically expressed in human male germ cells and potentially linked to rhogtpase signaling."
J. Biol. Chem. 276:20309-20315(2001) [PubMed] [Europe PMC] [Abstract].

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract].

"The testis anion transporter TAT1 (SLC26A8) physically and functionally interacts with the cystic fibrosis transmembrane conductance regulator channel: a potential role during sperm capacitation."
Hum. Mol. Genet. 21:1287-1298(2012) [PubMed] [Europe PMC] [Abstract]

"Mutational analysis of the human SLC26A8 gene: exclusion as a candidate for male infertility due to primary spermatogenic failure."
Mol. Hum. Reprod. 11:129-132(2005) [PubMed] [Europe PMC] [Abstract]

"The testis anion transporter 1 (Slc26a8) is required for sperm terminal differentiation and male fertility in the mouse."
Hum. Mol. Genet. 16:1783-1793(2007) [PubMed] [Europe PMC] [Abstract]

"Missense mutations in SLC26A8, encoding a sperm-specific activator of CFTR, are associated with human asthenozoospermia."
Am. J. Hum. Genet. 92:760-766(2013) [PubMed] [Europe PMC] [Abstract]