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Solute Carrier Family 30 Member 8 (SLC30A8)
Solute Carrier Family 30 Member 8 (SLC30A8)
ZNT8; Zinc Transporter 8
SLC30A8 is expressed at a high level only in the pancreas, particularly in islets of Langerhans. The protein colocalizes with insulin in the secretory pathway granules of the insulin-secreting INS-1 cells. Allelic variants of this gene exist that confer susceptibility to diabetes mellitus, noninsulin-dependent. Several transcript variants encoding different isoforms have been found for this gene.It was also expressed in fetal pancreas, islets of Langerhans, and an insulinoma cell line, but not in HeLa cells. Fluorescence-tagged ZNT8 was expressed in a punctate pattern in the cytoplasm of transfected insulinoma cells and HeLa cells. In insulinoma cells, ZNT8 expression overlapped that of insulin, suggesting that ZNT8 is associated with insulin granule secretion.
Organism species: Homo sapiens (Human)
Organism species: Mus musculus (Mouse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Solute Carrier Family 30 Member 8 (SLC30A8) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Solute Carrier Family 30 Member 8 (SLC30A8) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Solute Carrier Family 30 Member 8 (SLC30A8) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Solute Carrier Family 30 Member 8 (SLC30A8) CLIA assay for Antigen Detection
Organism species: Rattus norvegicus (Rat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Solute Carrier Family 30 Member 8 (SLC30A8) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Solute Carrier Family 30 Member 8 (SLC30A8) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Solute Carrier Family 30 Member 8 (SLC30A8) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Solute Carrier Family 30 Member 8 (SLC30A8) CLIA assay for Antigen Detection
Organism species: Canis familiaris; Canine (Dog)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Solute Carrier Family 30 Member 8 (SLC30A8) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Solute Carrier Family 30 Member 8 (SLC30A8) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Solute Carrier Family 30 Member 8 (SLC30A8) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Solute Carrier Family 30 Member 8 (SLC30A8) CLIA assay for Antigen Detection
Organism species: Sus scrofa; Porcine (Pig)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Solute Carrier Family 30 Member 8 (SLC30A8) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Solute Carrier Family 30 Member 8 (SLC30A8) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Solute Carrier Family 30 Member 8 (SLC30A8) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Solute Carrier Family 30 Member 8 (SLC30A8) CLIA assay for Antigen Detection
Organism species: Bos taurus; Bovine (Cattle)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Solute Carrier Family 30 Member 8 (SLC30A8) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Solute Carrier Family 30 Member 8 (SLC30A8) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Solute Carrier Family 30 Member 8 (SLC30A8) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Solute Carrier Family 30 Member 8 (SLC30A8) CLIA assay for Antigen Detection
Organism species: Rhesus monkey (Simian)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Solute Carrier Family 30 Member 8 (SLC30A8) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Solute Carrier Family 30 Member 8 (SLC30A8) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Solute Carrier Family 30 Member 8 (SLC30A8) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Solute Carrier Family 30 Member 8 (SLC30A8) CLIA assay for Antigen Detection
Organism species: Chicken (Gallus)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Solute Carrier Family 30 Member 8 (SLC30A8) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Solute Carrier Family 30 Member 8 (SLC30A8) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Solute Carrier Family 30 Member 8 (SLC30A8) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Solute Carrier Family 30 Member 8 (SLC30A8) CLIA assay for Antigen Detection
Organism species: Ovis aries; Ovine (Sheep)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Solute Carrier Family 30 Member 8 (SLC30A8) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Solute Carrier Family 30 Member 8 (SLC30A8) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Solute Carrier Family 30 Member 8 (SLC30A8) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Solute Carrier Family 30 Member 8 (SLC30A8) CLIA assay for Antigen Detection
Organism species: Oryctolagus cuniculus (Rabbit)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Solute Carrier Family 30 Member 8 (SLC30A8) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Solute Carrier Family 30 Member 8 (SLC30A8) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Solute Carrier Family 30 Member 8 (SLC30A8) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Solute Carrier Family 30 Member 8 (SLC30A8) CLIA assay for Antigen Detection
Organism species: Cavia (Guinea pig )
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Solute Carrier Family 30 Member 8 (SLC30A8) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Solute Carrier Family 30 Member 8 (SLC30A8) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Solute Carrier Family 30 Member 8 (SLC30A8) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Solute Carrier Family 30 Member 8 (SLC30A8) CLIA assay for Antigen Detection
Organism species: Equus caballus; Equine (Horse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Solute Carrier Family 30 Member 8 (SLC30A8) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Solute Carrier Family 30 Member 8 (SLC30A8) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Solute Carrier Family 30 Member 8 (SLC30A8) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Solute Carrier Family 30 Member 8 (SLC30A8) CLIA assay for Antigen Detection
Organism species: Capra hircus; Caprine (Goat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Solute Carrier Family 30 Member 8 (SLC30A8) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Solute Carrier Family 30 Member 8 (SLC30A8) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Solute Carrier Family 30 Member 8 (SLC30A8) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Solute Carrier Family 30 Member 8 (SLC30A8) CLIA assay for Antigen Detection
Organism species: Pan-species (General)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Solute Carrier Family 30 Member 8 (SLC30A8) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Solute Carrier Family 30 Member 8 (SLC30A8) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Solute Carrier Family 30 Member 8 (SLC30A8) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Solute Carrier Family 30 Member 8 (SLC30A8) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Solute Carrier Family 30 Member 8 (SLC30A8) CLIA assay for Antigen Detection
Reference
"Identification and cloning of a beta-cell-specific zinc transporter, ZnT-8, localized into insulin secretory granules." Diabetes 53:2330-2337(2004) [PubMed ] [Europe PMC ] [Abstract ]
"Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed ] [Europe PMC ] [Abstract ]
"The full-ORF clone resource of the German cDNA consortium." BMC Genomics 8:399-399(2007) [PubMed ] [Europe PMC ] [Abstract ]
"DNA sequence and analysis of human chromosome 8." Nature 439:331-335(2006) [PubMed ] [Europe PMC ] [Abstract ]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." Genome Res. 14:2121-2127(2004) [PubMed ] [Europe PMC ] [Abstract ]
"ZnT-8, a pancreatic beta-cell-specific zinc transporter." BioMetals 18:313-317(2005) [PubMed ] [Europe PMC ] [Abstract ]
"In vivo expression and functional characterization of the zinc transporter ZnT8 in glucose-induced insulin secretion." J. Cell Sci. 119:4199-4206(2006) [PubMed ] [Europe PMC ] [Abstract ]
"Zinc-transporter genes in human visceral and subcutaneous adipocytes: lean versus obese." Mol. Cell. Endocrinol. 264:68-73(2007) [PubMed ] [Europe PMC ] [Abstract ]
"Intracellular zinc homeostasis in leukocyte subsets is regulated by different expression of zinc exporters ZnT-1 to ZnT-9." J. Leukoc. Biol. 83:368-380(2008) [PubMed ] [Europe PMC ] [Abstract ]
"A genome-wide association study identifies novel risk loci for type 2 diabetes." Nature 445:881-885(2007) [PubMed ] [Europe PMC ] [Abstract ]
