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Gasdermin D (GSDMD)
Gasdermin D (GSDMD)
GSDMDC1; DF5L; Gasdermin Domain Containing 1
Gasdermin D is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. Gasdermin D has been suggested to act as a tumor suppressor. Alternatively spliced transcript variants have been described.
GSDM showed apoptotic activity upon expression in a human gastric cancer cell line. LMO1, RUNX3, and TGF-beta receptor II (TGFBR2) were coexpressed with GSDM in pit cells, and both LMO1 and RUNX3 bound to the GSDM promoter in vitro. TGF-beta (TGFB1) upregulated LMO1 and GSDM expression and induced apoptosis, and induction of apoptosis was inhibited by suppression of LMO1, RUNX3, and GSDM expression.
Organism species: Homo sapiens (Human)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Gasdermin D (GSDMD) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Gasdermin D (GSDMD) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Gasdermin D (GSDMD) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Gasdermin D (GSDMD) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Gasdermin D (GSDMD) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Gasdermin D (GSDMD) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Gasdermin D (GSDMD) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Gasdermin D (GSDMD) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Gasdermin D (GSDMD) Flow Cytometry;ICC/IF
Assay Kits
KES272Hu
ELISA Kit for Gasdermin D (GSDMD) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Gasdermin D (GSDMD) CLIA assay for Antigen Detection
Organism species: Mus musculus (Mouse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Gasdermin D (GSDMD) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Gasdermin D (GSDMD) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Gasdermin D (GSDMD) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Gasdermin D (GSDMD) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Gasdermin D (GSDMD) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Gasdermin D (GSDMD) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Gasdermin D (GSDMD) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Gasdermin D (GSDMD) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Gasdermin D (GSDMD) Flow Cytometry;ICC/IF
Assay Kits
KES272Mu
ELISA Kit for Gasdermin D (GSDMD) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Gasdermin D (GSDMD) CLIA assay for Antigen Detection
Organism species: Rattus norvegicus (Rat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Gasdermin D (GSDMD) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Gasdermin D (GSDMD) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Gasdermin D (GSDMD) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Gasdermin D (GSDMD) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Gasdermin D (GSDMD) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Gasdermin D (GSDMD) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Gasdermin D (GSDMD) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Gasdermin D (GSDMD) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Gasdermin D (GSDMD) Flow Cytometry;ICC/IF
Assay Kits
KES272Ra
ELISA Kit for Gasdermin D (GSDMD) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Gasdermin D (GSDMD) CLIA assay for Antigen Detection
Organism species: Canis familiaris; Canine (Dog)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Gasdermin D (GSDMD) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Gasdermin D (GSDMD) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Gasdermin D (GSDMD) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Gasdermin D (GSDMD) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Gasdermin D (GSDMD) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Gasdermin D (GSDMD) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Gasdermin D (GSDMD) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Gasdermin D (GSDMD) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Gasdermin D (GSDMD) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Gasdermin D (GSDMD) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Gasdermin D (GSDMD) CLIA assay for Antigen Detection
Organism species: Sus scrofa; Porcine (Pig)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Gasdermin D (GSDMD) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Gasdermin D (GSDMD) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Gasdermin D (GSDMD) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Gasdermin D (GSDMD) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Gasdermin D (GSDMD) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Gasdermin D (GSDMD) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Gasdermin D (GSDMD) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Gasdermin D (GSDMD) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Gasdermin D (GSDMD) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Gasdermin D (GSDMD) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Gasdermin D (GSDMD) CLIA assay for Antigen Detection
Organism species: Bos taurus; Bovine (Cattle)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Gasdermin D (GSDMD) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Gasdermin D (GSDMD) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Gasdermin D (GSDMD) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Gasdermin D (GSDMD) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Gasdermin D (GSDMD) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Gasdermin D (GSDMD) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Gasdermin D (GSDMD) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Gasdermin D (GSDMD) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Gasdermin D (GSDMD) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Gasdermin D (GSDMD) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Gasdermin D (GSDMD) CLIA assay for Antigen Detection
Organism species: Rhesus monkey (Simian)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Gasdermin D (GSDMD) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Gasdermin D (GSDMD) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Gasdermin D (GSDMD) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Gasdermin D (GSDMD) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Gasdermin D (GSDMD) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Gasdermin D (GSDMD) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Gasdermin D (GSDMD) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Gasdermin D (GSDMD) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Gasdermin D (GSDMD) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Gasdermin D (GSDMD) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Gasdermin D (GSDMD) CLIA assay for Antigen Detection
Organism species: Chicken (Gallus)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Gasdermin D (GSDMD) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Gasdermin D (GSDMD) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Gasdermin D (GSDMD) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Gasdermin D (GSDMD) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Gasdermin D (GSDMD) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Gasdermin D (GSDMD) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Gasdermin D (GSDMD) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Gasdermin D (GSDMD) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Gasdermin D (GSDMD) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Gasdermin D (GSDMD) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Gasdermin D (GSDMD) CLIA assay for Antigen Detection
Organism species: Ovis aries; Ovine (Sheep)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Gasdermin D (GSDMD) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Gasdermin D (GSDMD) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Gasdermin D (GSDMD) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Gasdermin D (GSDMD) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Gasdermin D (GSDMD) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Gasdermin D (GSDMD) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Gasdermin D (GSDMD) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Gasdermin D (GSDMD) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Gasdermin D (GSDMD) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Gasdermin D (GSDMD) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Gasdermin D (GSDMD) CLIA assay for Antigen Detection
Organism species: Oryctolagus cuniculus (Rabbit)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Gasdermin D (GSDMD) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Gasdermin D (GSDMD) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Gasdermin D (GSDMD) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Gasdermin D (GSDMD) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Gasdermin D (GSDMD) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Gasdermin D (GSDMD) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Gasdermin D (GSDMD) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Gasdermin D (GSDMD) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Gasdermin D (GSDMD) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Gasdermin D (GSDMD) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Gasdermin D (GSDMD) CLIA assay for Antigen Detection
Organism species: Cavia (Guinea pig )
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Gasdermin D (GSDMD) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Gasdermin D (GSDMD) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Gasdermin D (GSDMD) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Gasdermin D (GSDMD) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Gasdermin D (GSDMD) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Gasdermin D (GSDMD) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Gasdermin D (GSDMD) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Gasdermin D (GSDMD) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Gasdermin D (GSDMD) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Gasdermin D (GSDMD) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Gasdermin D (GSDMD) CLIA assay for Antigen Detection
Organism species: Equus caballus; Equine (Horse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Gasdermin D (GSDMD) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Gasdermin D (GSDMD) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Gasdermin D (GSDMD) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Gasdermin D (GSDMD) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Gasdermin D (GSDMD) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Gasdermin D (GSDMD) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Gasdermin D (GSDMD) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Gasdermin D (GSDMD) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Gasdermin D (GSDMD) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Gasdermin D (GSDMD) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Gasdermin D (GSDMD) CLIA assay for Antigen Detection
Organism species: Capra hircus; Caprine (Goat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Gasdermin D (GSDMD) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Gasdermin D (GSDMD) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Gasdermin D (GSDMD) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Gasdermin D (GSDMD) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Gasdermin D (GSDMD) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Gasdermin D (GSDMD) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Gasdermin D (GSDMD) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Gasdermin D (GSDMD) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Gasdermin D (GSDMD) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Gasdermin D (GSDMD) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Gasdermin D (GSDMD) CLIA assay for Antigen Detection
Organism species: Pan-species (General)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Gasdermin D (GSDMD) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Gasdermin D (GSDMD) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Gasdermin D (GSDMD) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Gasdermin D (GSDMD) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Gasdermin D (GSDMD) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Gasdermin D (GSDMD) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Gasdermin D (GSDMD) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Gasdermin D (GSDMD) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Gasdermin D (GSDMD) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Gasdermin D (GSDMD) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Gasdermin D (GSDMD) CLIA assay for Antigen Detection
Reference
"Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed ] [Europe PMC ] [Abstract ]
"DNA sequence and analysis of human chromosome 8." Nature 439:331-335(2006) [PubMed ] [Europe PMC ] [Abstract ]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." Genome Res. 14:2121-2127(2004) [PubMed ] [Europe PMC ] [Abstract ]
"Identification and characterization of human DFNA5L, mouse Dfna5l, and rat Dfna5l genes in silico." PubMed ] [Europe PMC ] [Abstract ]
"Immunoaffinity profiling of tyrosine phosphorylation in cancer cells." Nat. Biotechnol. 23:94-101(2005) [PubMed ] [Europe PMC ] [Abstract ]
"A quantitative atlas of mitotic phosphorylation." Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed ] [Europe PMC ] [Abstract ]
"Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions." Sci. Signal. 2:RA46-RA46(2009) [PubMed ] [Europe PMC ] [Abstract ]
"Initial characterization of the human central proteome." BMC Syst. Biol. 5:17-17(2011) [PubMed ] [Europe PMC ] [Abstract ]
"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome." J. Proteomics 96:253-262(2014) [PubMed ] [Europe PMC ] [Abstract ]
