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Tafazzin (TAZ)

CMD3A; EFE2; EFE; BTHS; XAP-2; G4.5; Barth syndrome; Endocardial Fibroelastosis 2; Cardiomyopathy,Dilated 3A(X-Linked)

Tafazzin a protein that is expressed at high levels in cardiac and skeletal muscle. Mutations in this gene have been associated with a number of clinical disorders including Barth syndrome, dilated cardiomyopathy (DCM), hypertrophic DCM, endocardial fibroelastosis, and left ventricular noncompaction (LVNC). Multiple transcript variants encoding different isoforms have been described.
A long form and a short form of each of these isoforms is produced; the short form lacks a hydrophobic leader sequence and may exist as a cytoplasmic protein rather than being membrane-bound. Other alternatively spliced transcripts have been described but the full-length nature of all these transcripts is not known.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins S237Hu01 Recombinant Tafazzin (TAZ) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Tafazzin (TAZ) Bioactivity
Antibodies MS237Hu21 Monoclonal Antibody to Tafazzin (TAZ) WB; IHC; ICC; IP.
PS237Hu01 Polyclonal Antibody to Tafazzin (TAZ) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Tafazzin (TAZ) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Tafazzin (TAZ) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Tafazzin (TAZ) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Tafazzin (TAZ) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Tafazzin (TAZ) Flow Cytometry;ICC/IF
Assay Kits KES237Hu ELISA Kit for Tafazzin (TAZ) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Tafazzin (TAZ) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Tafazzin (TAZ) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Tafazzin (TAZ) Bioactivity
Antibodies NONE Monoclonal Antibody to Tafazzin (TAZ) WB; IHC; ICC; IP.
PS237Mu01 Polyclonal Antibody to Tafazzin (TAZ) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Tafazzin (TAZ) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Tafazzin (TAZ) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Tafazzin (TAZ) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Tafazzin (TAZ) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Tafazzin (TAZ) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Tafazzin (TAZ) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Tafazzin (TAZ) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Tafazzin (TAZ) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Tafazzin (TAZ) Bioactivity
Antibodies NONE Monoclonal Antibody to Tafazzin (TAZ) WB; IHC; ICC; IP.
PS237Ra01 Polyclonal Antibody to Tafazzin (TAZ) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Tafazzin (TAZ) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Tafazzin (TAZ) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Tafazzin (TAZ) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Tafazzin (TAZ) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Tafazzin (TAZ) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Tafazzin (TAZ) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Tafazzin (TAZ) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Tafazzin (TAZ) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Tafazzin (TAZ) Bioactivity
Antibodies NONE Monoclonal Antibody to Tafazzin (TAZ) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Tafazzin (TAZ) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Tafazzin (TAZ) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Tafazzin (TAZ) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Tafazzin (TAZ) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Tafazzin (TAZ) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Tafazzin (TAZ) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Tafazzin (TAZ) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Tafazzin (TAZ) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Tafazzin (TAZ) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Tafazzin (TAZ) Bioactivity
Antibodies NONE Monoclonal Antibody to Tafazzin (TAZ) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Tafazzin (TAZ) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Tafazzin (TAZ) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Tafazzin (TAZ) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Tafazzin (TAZ) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Tafazzin (TAZ) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Tafazzin (TAZ) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Tafazzin (TAZ) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Tafazzin (TAZ) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Tafazzin (TAZ) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Tafazzin (TAZ) Bioactivity
Antibodies NONE Monoclonal Antibody to Tafazzin (TAZ) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Tafazzin (TAZ) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Tafazzin (TAZ) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Tafazzin (TAZ) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Tafazzin (TAZ) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Tafazzin (TAZ) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Tafazzin (TAZ) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Tafazzin (TAZ) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Tafazzin (TAZ) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Tafazzin (TAZ) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Tafazzin (TAZ) Bioactivity
Antibodies NONE Monoclonal Antibody to Tafazzin (TAZ) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Tafazzin (TAZ) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Tafazzin (TAZ) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Tafazzin (TAZ) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Tafazzin (TAZ) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Tafazzin (TAZ) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Tafazzin (TAZ) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Tafazzin (TAZ) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Tafazzin (TAZ) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Tafazzin (TAZ) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Tafazzin (TAZ) Bioactivity
Antibodies NONE Monoclonal Antibody to Tafazzin (TAZ) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Tafazzin (TAZ) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Tafazzin (TAZ) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Tafazzin (TAZ) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Tafazzin (TAZ) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Tafazzin (TAZ) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Tafazzin (TAZ) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Tafazzin (TAZ) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Tafazzin (TAZ) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Tafazzin (TAZ) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Tafazzin (TAZ) Bioactivity
Antibodies NONE Monoclonal Antibody to Tafazzin (TAZ) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Tafazzin (TAZ) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Tafazzin (TAZ) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Tafazzin (TAZ) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Tafazzin (TAZ) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Tafazzin (TAZ) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Tafazzin (TAZ) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Tafazzin (TAZ) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Tafazzin (TAZ) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Tafazzin (TAZ) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Tafazzin (TAZ) Bioactivity
Antibodies NONE Monoclonal Antibody to Tafazzin (TAZ) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Tafazzin (TAZ) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Tafazzin (TAZ) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Tafazzin (TAZ) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Tafazzin (TAZ) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Tafazzin (TAZ) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Tafazzin (TAZ) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Tafazzin (TAZ) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Tafazzin (TAZ) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Tafazzin (TAZ) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Tafazzin (TAZ) Bioactivity
Antibodies NONE Monoclonal Antibody to Tafazzin (TAZ) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Tafazzin (TAZ) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Tafazzin (TAZ) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Tafazzin (TAZ) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Tafazzin (TAZ) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Tafazzin (TAZ) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Tafazzin (TAZ) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Tafazzin (TAZ) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Tafazzin (TAZ) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Tafazzin (TAZ) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Tafazzin (TAZ) Bioactivity
Antibodies NONE Monoclonal Antibody to Tafazzin (TAZ) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Tafazzin (TAZ) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Tafazzin (TAZ) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Tafazzin (TAZ) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Tafazzin (TAZ) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Tafazzin (TAZ) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Tafazzin (TAZ) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Tafazzin (TAZ) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Tafazzin (TAZ) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Tafazzin (TAZ) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Tafazzin (TAZ) Bioactivity
Antibodies NONE Monoclonal Antibody to Tafazzin (TAZ) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Tafazzin (TAZ) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Tafazzin (TAZ) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Tafazzin (TAZ) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Tafazzin (TAZ) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Tafazzin (TAZ) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Tafazzin (TAZ) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Tafazzin (TAZ) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Tafazzin (TAZ) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Tafazzin (TAZ) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Tafazzin (TAZ) Bioactivity
Antibodies NONE Monoclonal Antibody to Tafazzin (TAZ) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Tafazzin (TAZ) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Tafazzin (TAZ) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Tafazzin (TAZ) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Tafazzin (TAZ) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Tafazzin (TAZ) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Tafazzin (TAZ) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Tafazzin (TAZ) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Tafazzin (TAZ) CLIA assay for Antigen Detection

Reference

"A novel X-linked gene, G4.5. is responsible for Barth syndrome."
Nat. Genet. 12:385-389(1996) [PubMed] [Europe PMC] [Abstract]

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence of the human X chromosome."
Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]

"Only one splice variant of the human TAZ gene encodes a functional protein with a role in cardiolipin metabolism."
J. Biol. Chem. 278:43089-43094(2003) [PubMed] [Europe PMC] [Abstract]

"Role of calcium-independent phospholipase A2 in the pathogenesis of Barth syndrome."
Proc. Natl. Acad. Sci. U.S.A. 106:2337-2341(2009) [PubMed] [Europe PMC] [Abstract]

"The X-linked gene G4.5 is responsible for different infantile dilated cardiomyopathies."
Am. J. Hum. Genet. 61:862-867(1997) [PubMed] [Europe PMC] [Abstract]

"Neonatal, lethal noncompaction of the left ventricular myocardium is allelic with Barth syndrome."
Am. J. Hum. Genet. 61:868-872(1997) [PubMed] [Europe PMC] [Abstract]

"Novel gene mutations in patients with left ventricular noncompaction or Barth syndrome."
Circulation 103:1256-1263(2001) [PubMed] [Europe PMC] [Abstract]

"Novel missense mutation (R94S) in the TAZ (G4.5) gene in a Japanese patient with Barth syndrome."
J. Hum. Genet. 47:229-231(2002) [PubMed] [Europe PMC] [Abstract]