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Fascin 2 (FSCN2)

RFSN; RP30; Actin-Bundling Protein,Retinal,Strongylocentrotus Purpuratus

Fascin-2 is a member of the fascin protein family. Fascins crosslink actin into filamentous bundles within dynamic cell extensions. This family member is proposed to play a role in photoreceptor disk morphogenesis. A mutation in this gene results in one form of autosomal dominant retinitis pigmentosa and macular degeneration. Multiple transcript variants encoding different isoforms have been found for this gene.FSCN2 shares 56% amino acid identity with FSCN1 and 94% identity with bovine retinal fascin. The largest block of conserved sequence between human and bovine FSCN2 includes a putative phosphorylation site at ser39. FSCN2 also shares significant similarity with several other vertebrate and invertebrate fascins. Northern blot analysis of bovine tissues detected Fscn2 expression only in retina.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins S179Hu01 Recombinant Fascin 2 (FSCN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Fascin 2 (FSCN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Fascin 2 (FSCN2) WB; IHC; ICC; IP.
PS179Hu01 Polyclonal Antibody to Fascin 2 (FSCN2) WB; IHC; ICC; IF.
LS179Hu71 Biotin Linked-Polyclonal Antibody to Fascin 2 (FSCN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Fascin 2 (FSCN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Fascin 2 (FSCN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Fascin 2 (FSCN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Fascin 2 (FSCN2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Fascin 2 (FSCN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Fascin 2 (FSCN2) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins S179Mu01 Recombinant Fascin 2 (FSCN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Fascin 2 (FSCN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Fascin 2 (FSCN2) WB; IHC; ICC; IP.
PS179Mu01 Polyclonal Antibody to Fascin 2 (FSCN2) WB; IHC; ICC; IF.
LS179Mu71 Biotin Linked-Polyclonal Antibody to Fascin 2 (FSCN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Fascin 2 (FSCN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Fascin 2 (FSCN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Fascin 2 (FSCN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Fascin 2 (FSCN2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Fascin 2 (FSCN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Fascin 2 (FSCN2) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Fascin 2 (FSCN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Fascin 2 (FSCN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Fascin 2 (FSCN2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Fascin 2 (FSCN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Fascin 2 (FSCN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Fascin 2 (FSCN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Fascin 2 (FSCN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Fascin 2 (FSCN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Fascin 2 (FSCN2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Fascin 2 (FSCN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Fascin 2 (FSCN2) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Fascin 2 (FSCN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Fascin 2 (FSCN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Fascin 2 (FSCN2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Fascin 2 (FSCN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Fascin 2 (FSCN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Fascin 2 (FSCN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Fascin 2 (FSCN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Fascin 2 (FSCN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Fascin 2 (FSCN2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Fascin 2 (FSCN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Fascin 2 (FSCN2) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Fascin 2 (FSCN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Fascin 2 (FSCN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Fascin 2 (FSCN2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Fascin 2 (FSCN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Fascin 2 (FSCN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Fascin 2 (FSCN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Fascin 2 (FSCN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Fascin 2 (FSCN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Fascin 2 (FSCN2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Fascin 2 (FSCN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Fascin 2 (FSCN2) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Fascin 2 (FSCN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Fascin 2 (FSCN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Fascin 2 (FSCN2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Fascin 2 (FSCN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Fascin 2 (FSCN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Fascin 2 (FSCN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Fascin 2 (FSCN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Fascin 2 (FSCN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Fascin 2 (FSCN2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Fascin 2 (FSCN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Fascin 2 (FSCN2) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Fascin 2 (FSCN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Fascin 2 (FSCN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Fascin 2 (FSCN2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Fascin 2 (FSCN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Fascin 2 (FSCN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Fascin 2 (FSCN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Fascin 2 (FSCN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Fascin 2 (FSCN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Fascin 2 (FSCN2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Fascin 2 (FSCN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Fascin 2 (FSCN2) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Fascin 2 (FSCN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Fascin 2 (FSCN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Fascin 2 (FSCN2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Fascin 2 (FSCN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Fascin 2 (FSCN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Fascin 2 (FSCN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Fascin 2 (FSCN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Fascin 2 (FSCN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Fascin 2 (FSCN2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Fascin 2 (FSCN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Fascin 2 (FSCN2) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Fascin 2 (FSCN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Fascin 2 (FSCN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Fascin 2 (FSCN2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Fascin 2 (FSCN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Fascin 2 (FSCN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Fascin 2 (FSCN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Fascin 2 (FSCN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Fascin 2 (FSCN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Fascin 2 (FSCN2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Fascin 2 (FSCN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Fascin 2 (FSCN2) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Fascin 2 (FSCN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Fascin 2 (FSCN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Fascin 2 (FSCN2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Fascin 2 (FSCN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Fascin 2 (FSCN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Fascin 2 (FSCN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Fascin 2 (FSCN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Fascin 2 (FSCN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Fascin 2 (FSCN2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Fascin 2 (FSCN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Fascin 2 (FSCN2) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Fascin 2 (FSCN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Fascin 2 (FSCN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Fascin 2 (FSCN2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Fascin 2 (FSCN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Fascin 2 (FSCN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Fascin 2 (FSCN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Fascin 2 (FSCN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Fascin 2 (FSCN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Fascin 2 (FSCN2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Fascin 2 (FSCN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Fascin 2 (FSCN2) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Fascin 2 (FSCN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Fascin 2 (FSCN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Fascin 2 (FSCN2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Fascin 2 (FSCN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Fascin 2 (FSCN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Fascin 2 (FSCN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Fascin 2 (FSCN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Fascin 2 (FSCN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Fascin 2 (FSCN2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Fascin 2 (FSCN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Fascin 2 (FSCN2) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Fascin 2 (FSCN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Fascin 2 (FSCN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Fascin 2 (FSCN2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Fascin 2 (FSCN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Fascin 2 (FSCN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Fascin 2 (FSCN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Fascin 2 (FSCN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Fascin 2 (FSCN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Fascin 2 (FSCN2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Fascin 2 (FSCN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Fascin 2 (FSCN2) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Fascin 2 (FSCN2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Fascin 2 (FSCN2) Bioactivity
Antibodies NONE Monoclonal Antibody to Fascin 2 (FSCN2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Fascin 2 (FSCN2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Fascin 2 (FSCN2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Fascin 2 (FSCN2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Fascin 2 (FSCN2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Fascin 2 (FSCN2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Fascin 2 (FSCN2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Fascin 2 (FSCN2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Fascin 2 (FSCN2) CLIA assay for Antigen Detection

Reference

"Refinement of the RP17 locus for autosomal dominant retinitis pigmentosa, construction of a YAC contig and investigation of the candidate gene retinal fascin."
Eur. J. Hum. Genet. 7:332-338(1999) [PubMed] [Europe PMC] [Abstract]

"Characterization of human retinal fascin gene (FSCN2) at 17q25: close physical linkage of fascin and cytoplasmic actin genes."
Genomics 65:146-156(2000) [PubMed] [Europe PMC] [Abstract]

"DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage."
Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Retinal fascin: functional nature, subcellular distribution, and chromosomal localization."
Invest. Ophthalmol. Vis. Sci. 41:2087-2095(2000) [PubMed] [Europe PMC] [Abstract]

"Mutation of human retinal fascin gene (FSCN2) causes autosomal dominant retinitis pigmentosa."
Invest. Ophthalmol. Vis. Sci. 42:2395-2400(2001) [PubMed] [Europe PMC] [Abstract]