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Guanylate Binding Protein 5 (GBP5)
Guanylate Binding Protein 5 (GBP5)
GBP-TA antigen GTP-binding protein 5; Guanine nucleotide-binding protein 5
Like all GBPs, GBP5 has a conserved N-terminal globular GTP-binding domain containing 2 consensus sequences and a third T(L/V)RD sequence not found in other GTPases. Like GBP1 and GBP2, GBP5 has a C-terminal CaaX isoprenylation motif. EST database analysis indicated wide expression of GBP5 in human tissues. Immunofluorescence analysis demonstrated cytoplasmic expression of GBP5. Irrespective of stimulation, GBP5 was constitutively expressed in the Golgi apparatus.The GBP5ta splice variant lacks exons 11 and 12 leading to C-terminal deletion of 97 amino acids and loss of a putative isoprenylation site. The GBP5a variant lacks the noncoding exon 2.The deduced 586-amino acid protein has a predicted molecular mass of 67 kD and contains a guanylate-binding site composed of 3 motifs.
Organism species: Homo sapiens (Human)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
S137Hu01
Recombinant Guanylate Binding Protein 5 (GBP5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Guanylate Binding Protein 5 (GBP5) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Guanylate Binding Protein 5 (GBP5) WB; IHC; ICC; IP.
PS137Hu01
Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Guanylate Binding Protein 5 (GBP5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Guanylate Binding Protein 5 (GBP5) CLIA assay for Antigen Detection
Organism species: Mus musculus (Mouse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Guanylate Binding Protein 5 (GBP5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Guanylate Binding Protein 5 (GBP5) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Guanylate Binding Protein 5 (GBP5) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Guanylate Binding Protein 5 (GBP5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Guanylate Binding Protein 5 (GBP5) CLIA assay for Antigen Detection
Organism species: Rattus norvegicus (Rat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
S137Ra01
Recombinant Guanylate Binding Protein 5 (GBP5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Guanylate Binding Protein 5 (GBP5) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Guanylate Binding Protein 5 (GBP5) WB; IHC; ICC; IP.
PS137Ra01
Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Guanylate Binding Protein 5 (GBP5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Guanylate Binding Protein 5 (GBP5) CLIA assay for Antigen Detection
Organism species: Canis familiaris; Canine (Dog)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Guanylate Binding Protein 5 (GBP5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Guanylate Binding Protein 5 (GBP5) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Guanylate Binding Protein 5 (GBP5) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Guanylate Binding Protein 5 (GBP5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Guanylate Binding Protein 5 (GBP5) CLIA assay for Antigen Detection
Organism species: Sus scrofa; Porcine (Pig)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Guanylate Binding Protein 5 (GBP5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Guanylate Binding Protein 5 (GBP5) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Guanylate Binding Protein 5 (GBP5) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Guanylate Binding Protein 5 (GBP5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Guanylate Binding Protein 5 (GBP5) CLIA assay for Antigen Detection
Organism species: Bos taurus; Bovine (Cattle)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Guanylate Binding Protein 5 (GBP5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Guanylate Binding Protein 5 (GBP5) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Guanylate Binding Protein 5 (GBP5) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Guanylate Binding Protein 5 (GBP5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Guanylate Binding Protein 5 (GBP5) CLIA assay for Antigen Detection
Organism species: Rhesus monkey (Simian)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Guanylate Binding Protein 5 (GBP5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Guanylate Binding Protein 5 (GBP5) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Guanylate Binding Protein 5 (GBP5) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Guanylate Binding Protein 5 (GBP5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Guanylate Binding Protein 5 (GBP5) CLIA assay for Antigen Detection
Organism species: Chicken (Gallus)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Guanylate Binding Protein 5 (GBP5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Guanylate Binding Protein 5 (GBP5) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Guanylate Binding Protein 5 (GBP5) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Guanylate Binding Protein 5 (GBP5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Guanylate Binding Protein 5 (GBP5) CLIA assay for Antigen Detection
Organism species: Ovis aries; Ovine (Sheep)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Guanylate Binding Protein 5 (GBP5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Guanylate Binding Protein 5 (GBP5) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Guanylate Binding Protein 5 (GBP5) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Guanylate Binding Protein 5 (GBP5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Guanylate Binding Protein 5 (GBP5) CLIA assay for Antigen Detection
Organism species: Oryctolagus cuniculus (Rabbit)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Guanylate Binding Protein 5 (GBP5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Guanylate Binding Protein 5 (GBP5) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Guanylate Binding Protein 5 (GBP5) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Guanylate Binding Protein 5 (GBP5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Guanylate Binding Protein 5 (GBP5) CLIA assay for Antigen Detection
Organism species: Cavia (Guinea pig )
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Guanylate Binding Protein 5 (GBP5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Guanylate Binding Protein 5 (GBP5) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Guanylate Binding Protein 5 (GBP5) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Guanylate Binding Protein 5 (GBP5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Guanylate Binding Protein 5 (GBP5) CLIA assay for Antigen Detection
Organism species: Equus caballus; Equine (Horse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Guanylate Binding Protein 5 (GBP5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Guanylate Binding Protein 5 (GBP5) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Guanylate Binding Protein 5 (GBP5) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Guanylate Binding Protein 5 (GBP5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Guanylate Binding Protein 5 (GBP5) CLIA assay for Antigen Detection
Organism species: Capra hircus; Caprine (Goat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Guanylate Binding Protein 5 (GBP5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Guanylate Binding Protein 5 (GBP5) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Guanylate Binding Protein 5 (GBP5) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Guanylate Binding Protein 5 (GBP5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Guanylate Binding Protein 5 (GBP5) CLIA assay for Antigen Detection
Organism species: Pan-species (General)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Guanylate Binding Protein 5 (GBP5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Guanylate Binding Protein 5 (GBP5) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Guanylate Binding Protein 5 (GBP5) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Guanylate Binding Protein 5 (GBP5) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Guanylate Binding Protein 5 (GBP5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Guanylate Binding Protein 5 (GBP5) CLIA assay for Antigen Detection
Reference
"GBP-5 splicing variants: New guanylate-binding proteins with tumor-associated expression and antigenicity." J. Invest. Dermatol. 122:1510-1517(2004) [PubMed ] [Europe PMC ] [Abstract ]
"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Genome Res. 13:2265-2270(2003) [PubMed ] [Europe PMC ] [Abstract ]
"Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed ] [Europe PMC ] [Abstract ]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." Genome Res. 14:2121-2127(2004) [PubMed ] [Europe PMC ] [Abstract ]
"Unique features of different members of the human guanylate-binding protein family." J. Interferon Cytokine Res. 27:44-52(2007) [PubMed ] [Europe PMC ] [Abstract ]
"Intracellular trafficking of guanylate-binding proteins is regulated by heterodimerization in a hierarchical manner." PLoS ONE 5:E14246-E14246(2010) [PubMed ] [Europe PMC ] [Abstract ]
"GBP5 promotes NLRP3 inflammasome assembly and immunity in mammals." Science 336:481-485(2012) [PubMed ] [Europe PMC ] [Abstract ]
