Guanylate Binding Protein 3 (GBP3)

GTP-binding protein 3; Guanine nucleotide-binding protein 3

SPN	S136
HGNC	4184
UniProt	Q9H0R5

GBP3 encodes a member of the guanylate-binding protein (GBP) family. GBPs specifically bind guanine nucleotides (GMP, GDP, and GTP) and contain two of the three consensus motifs found in typical GTP-binding proteins. The encoded protein interacts with a member of the germinal center kinase family.
Olszewski et al. (2006) reported that the 595-amino acid GBP3 protein shares 88% and 76% identity with GBP1 and GBP2, respectively. All GBPs, including GBP3, have a conserved N-terminal globular GTP-binding domain containing 2 consensus sequences and a third T(L/V)RD sequence not found in other GTPases. GBP3 lacks the C-terminal CaaX isoprenylation motif found in GBP1, GBP2, and GBP5. EST database analysis indicated wide expression of GBP3 in human tissues.

Organism species: Homo sapiens (Human)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	S136Hu01	Recombinant Guanylate Binding Protein 3 (GBP3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Guanylate Binding Protein 3 (GBP3)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Guanylate Binding Protein 3 (GBP3)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Guanylate Binding Protein 3 (GBP3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Guanylate Binding Protein 3 (GBP3)	CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	S136Mu01	Recombinant Guanylate Binding Protein 3 (GBP3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Guanylate Binding Protein 3 (GBP3)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Guanylate Binding Protein 3 (GBP3)	WB; IHC; ICC; IP.
	PS136Mu01	Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Guanylate Binding Protein 3 (GBP3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Guanylate Binding Protein 3 (GBP3)	CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Guanylate Binding Protein 3 (GBP3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Guanylate Binding Protein 3 (GBP3)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Guanylate Binding Protein 3 (GBP3)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Guanylate Binding Protein 3 (GBP3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Guanylate Binding Protein 3 (GBP3)	CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Guanylate Binding Protein 3 (GBP3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Guanylate Binding Protein 3 (GBP3)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Guanylate Binding Protein 3 (GBP3)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Guanylate Binding Protein 3 (GBP3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Guanylate Binding Protein 3 (GBP3)	CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Guanylate Binding Protein 3 (GBP3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Guanylate Binding Protein 3 (GBP3)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Guanylate Binding Protein 3 (GBP3)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Guanylate Binding Protein 3 (GBP3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Guanylate Binding Protein 3 (GBP3)	CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Guanylate Binding Protein 3 (GBP3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Guanylate Binding Protein 3 (GBP3)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Guanylate Binding Protein 3 (GBP3)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Guanylate Binding Protein 3 (GBP3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Guanylate Binding Protein 3 (GBP3)	CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Guanylate Binding Protein 3 (GBP3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Guanylate Binding Protein 3 (GBP3)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Guanylate Binding Protein 3 (GBP3)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Guanylate Binding Protein 3 (GBP3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Guanylate Binding Protein 3 (GBP3)	CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Guanylate Binding Protein 3 (GBP3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Guanylate Binding Protein 3 (GBP3)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Guanylate Binding Protein 3 (GBP3)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Guanylate Binding Protein 3 (GBP3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Guanylate Binding Protein 3 (GBP3)	CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Guanylate Binding Protein 3 (GBP3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Guanylate Binding Protein 3 (GBP3)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Guanylate Binding Protein 3 (GBP3)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Guanylate Binding Protein 3 (GBP3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Guanylate Binding Protein 3 (GBP3)	CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Guanylate Binding Protein 3 (GBP3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Guanylate Binding Protein 3 (GBP3)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Guanylate Binding Protein 3 (GBP3)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Guanylate Binding Protein 3 (GBP3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Guanylate Binding Protein 3 (GBP3)	CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Guanylate Binding Protein 3 (GBP3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Guanylate Binding Protein 3 (GBP3)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Guanylate Binding Protein 3 (GBP3)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Guanylate Binding Protein 3 (GBP3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Guanylate Binding Protein 3 (GBP3)	CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Guanylate Binding Protein 3 (GBP3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Guanylate Binding Protein 3 (GBP3)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Guanylate Binding Protein 3 (GBP3)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Guanylate Binding Protein 3 (GBP3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Guanylate Binding Protein 3 (GBP3)	CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Guanylate Binding Protein 3 (GBP3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Guanylate Binding Protein 3 (GBP3)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Guanylate Binding Protein 3 (GBP3)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Guanylate Binding Protein 3 (GBP3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Guanylate Binding Protein 3 (GBP3)	CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE	CATALOG NO.	PRODUCT NAME	APPLICATIONS
Proteins	NONE	Recombinant Guanylate Binding Protein 3 (GBP3)	Positive Control; Immunogen; SDS-PAGE; WB.
Proteins	NONE	Native Guanylate Binding Protein 3 (GBP3)	Bioactivity
Antibodies	NONE	Monoclonal Antibody to Guanylate Binding Protein 3 (GBP3)	WB; IHC; ICC; IP.
	NONE	Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	WB; IHC; ICC; IF.
	NONE	Biotin Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	ELISA(Det);IC; IH; IH(P); WB
	NONE	APC Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	IHC, WB
	NONE	HRP Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	Simple Western; WB
	NONE	PE Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	Flow Cytometry
	NONE	FITC Linked-Polyclonal Antibody to Guanylate Binding Protein 3 (GBP3)	Flow Cytometry;ICC/IF
Assay Kits	NONE	ELISA Kit for Guanylate Binding Protein 3 (GBP3)	Enzyme-linked immunosorbent assay for Antigen Detection
Assay Kits	NONE	CLIA kit for Guanylate Binding Protein 3 (GBP3)	CLIA assay for Antigen Detection

Reference

"A new splice variant of the human guanylate-binding protein 3 mediates anti-influenza activity through inhibition of viral transcription and replication."
FASEB J. 26:1290-1300(2012) [PubMed] [Europe PMC] [Abstract]

"Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs."
Genome Res. 11:422-435(2001) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence and biological annotation of human chromosome 1."
Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Unique features of different members of the human guanylate-binding protein family."
J. Interferon Cytokine Res. 27:44-52(2007) [PubMed] [Europe PMC] [Abstract]