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Karyopherin Alpha 1 (KPNa1)

IPOA5; NPI-1; RCH2; SRP1; importin alpha 5; Nucleoprotein interactor 1; RAG cohort protein 2; SRP1-beta

Recombination activating proteins RAG1 and RAG2 regulate and mediate V(D)J recombination, the process by which genes for immunoglobulins and T-cell receptors are generated. Several other ubiquitously expressed proteins are thought to be recruited in the recombination process. Among these are the genes affected in severe combined immune deficiency and genes involved in ds-DNA break repair. KPNa1 interacts with RAG1 and may play a role in V(D)J recombination. The authors obtained human and mouse cDNA sequences which are 98% identical as proteins. When RAG1 and human SRP1 were cotransfected into 293T cells a stable complex of the 2 was observed. The authors speculated that because SRP1 appears to be bound to the nuclear envelope, the interaction with RAG1 may serve to localize that protein to the envelope as well.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Karyopherin Alpha 1 (KPNa1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Karyopherin Alpha 1 (KPNa1) Bioactivity
Antibodies NONE Monoclonal Antibody to Karyopherin Alpha 1 (KPNa1) WB; IHC; ICC; IP.
PS066Hu01 Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Karyopherin Alpha 1 (KPNa1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Karyopherin Alpha 1 (KPNa1) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Karyopherin Alpha 1 (KPNa1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Karyopherin Alpha 1 (KPNa1) Bioactivity
Antibodies NONE Monoclonal Antibody to Karyopherin Alpha 1 (KPNa1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Karyopherin Alpha 1 (KPNa1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Karyopherin Alpha 1 (KPNa1) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Karyopherin Alpha 1 (KPNa1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Karyopherin Alpha 1 (KPNa1) Bioactivity
Antibodies NONE Monoclonal Antibody to Karyopherin Alpha 1 (KPNa1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Karyopherin Alpha 1 (KPNa1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Karyopherin Alpha 1 (KPNa1) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Karyopherin Alpha 1 (KPNa1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Karyopherin Alpha 1 (KPNa1) Bioactivity
Antibodies NONE Monoclonal Antibody to Karyopherin Alpha 1 (KPNa1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Karyopherin Alpha 1 (KPNa1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Karyopherin Alpha 1 (KPNa1) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Karyopherin Alpha 1 (KPNa1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Karyopherin Alpha 1 (KPNa1) Bioactivity
Antibodies NONE Monoclonal Antibody to Karyopherin Alpha 1 (KPNa1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Karyopherin Alpha 1 (KPNa1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Karyopherin Alpha 1 (KPNa1) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Karyopherin Alpha 1 (KPNa1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Karyopherin Alpha 1 (KPNa1) Bioactivity
Antibodies NONE Monoclonal Antibody to Karyopherin Alpha 1 (KPNa1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Karyopherin Alpha 1 (KPNa1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Karyopherin Alpha 1 (KPNa1) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Karyopherin Alpha 1 (KPNa1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Karyopherin Alpha 1 (KPNa1) Bioactivity
Antibodies NONE Monoclonal Antibody to Karyopherin Alpha 1 (KPNa1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Karyopherin Alpha 1 (KPNa1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Karyopherin Alpha 1 (KPNa1) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Karyopherin Alpha 1 (KPNa1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Karyopherin Alpha 1 (KPNa1) Bioactivity
Antibodies NONE Monoclonal Antibody to Karyopherin Alpha 1 (KPNa1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Karyopherin Alpha 1 (KPNa1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Karyopherin Alpha 1 (KPNa1) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Karyopherin Alpha 1 (KPNa1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Karyopherin Alpha 1 (KPNa1) Bioactivity
Antibodies NONE Monoclonal Antibody to Karyopherin Alpha 1 (KPNa1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Karyopherin Alpha 1 (KPNa1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Karyopherin Alpha 1 (KPNa1) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Karyopherin Alpha 1 (KPNa1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Karyopherin Alpha 1 (KPNa1) Bioactivity
Antibodies NONE Monoclonal Antibody to Karyopherin Alpha 1 (KPNa1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Karyopherin Alpha 1 (KPNa1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Karyopherin Alpha 1 (KPNa1) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Karyopherin Alpha 1 (KPNa1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Karyopherin Alpha 1 (KPNa1) Bioactivity
Antibodies NONE Monoclonal Antibody to Karyopherin Alpha 1 (KPNa1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Karyopherin Alpha 1 (KPNa1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Karyopherin Alpha 1 (KPNa1) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Karyopherin Alpha 1 (KPNa1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Karyopherin Alpha 1 (KPNa1) Bioactivity
Antibodies NONE Monoclonal Antibody to Karyopherin Alpha 1 (KPNa1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Karyopherin Alpha 1 (KPNa1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Karyopherin Alpha 1 (KPNa1) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Karyopherin Alpha 1 (KPNa1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Karyopherin Alpha 1 (KPNa1) Bioactivity
Antibodies NONE Monoclonal Antibody to Karyopherin Alpha 1 (KPNa1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Karyopherin Alpha 1 (KPNa1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Karyopherin Alpha 1 (KPNa1) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Karyopherin Alpha 1 (KPNa1) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Karyopherin Alpha 1 (KPNa1) Bioactivity
Antibodies NONE Monoclonal Antibody to Karyopherin Alpha 1 (KPNa1) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Karyopherin Alpha 1 (KPNa1) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Karyopherin Alpha 1 (KPNa1) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Karyopherin Alpha 1 (KPNa1) CLIA assay for Antigen Detection

Reference

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"A nonconventional nuclear localization signal within the UL84 protein of human cytomegalovirus mediates nuclear import via the importin alpha/beta pathway."
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"Analysis of nuclear transport signals in the human apurinic/apyrimidinic endonuclease (APE1/Ref1)."
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"Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."
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