Interferon Gamma Inducible Protein 30 (IFI30)
GILT; IP30; Legumaturain; Gamma-Interferon-Inducible Lysosomal Thiol Reductase; Gamma-interferon-inducible lysosomal thiol reductase
Gamma-interferon-inducible lysosomal thiol reductase is a lysosomal thiol reductase that at low pH can reduce protein disulfide bonds. The enzyme is expressed constitutively in antigen-presenting cells and induced by gamma-interferon in other cell types. This enzyme has an important role in MHC class II-restricted antigen processing.
Arunachalam et al. (2000) described a lysosomal thiol reductase, which they called GILT, that was optimally active at low pH and capable of catalyzing disulfide bond reduction both in vivo and in vitro. They found that the GILT gene encodes a predicted 261-amino acid protein composed of a 37-amino acid signal peptide and a 224-amino acid proform.
Organism species: Homo sapiens (Human)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS051Hu01 | Recombinant Interferon Gamma Inducible Protein 30 (IFI30) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS051Hu01 | Monoclonal Antibody to Interferon Gamma Inducible Protein 30 (IFI30) | WB; IHC; ICC; IP. |
| PAS051Hu01 | Polyclonal Antibody to Interferon Gamma Inducible Protein 30 (IFI30) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS051Hu01 | CLIA Kit for Interferon Gamma Inducible Protein 30 (IFI30) | CLIA assay for Antigen Detection |
| ELS051Hu01 | ELISA Kit for Interferon Gamma Inducible Protein 30 (IFI30) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Mus musculus (Mouse)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS051Mu01 | Recombinant Interferon Gamma Inducible Protein 30 (IFI30) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS051Mu01 | Monoclonal Antibody to Interferon Gamma Inducible Protein 30 (IFI30) | WB; IHC; ICC; IP. |
| PAS051Mu01 | Polyclonal Antibody to Interferon Gamma Inducible Protein 30 (IFI30) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS051Mu01 | CLIA Kit for Interferon Gamma Inducible Protein 30 (IFI30) | CLIA assay for Antigen Detection |
| ELS051Mu01 | ELISA Kit for Interferon Gamma Inducible Protein 30 (IFI30) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rattus norvegicus (Rat)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS051Ra01 | Recombinant Interferon Gamma Inducible Protein 30 (IFI30) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS051Ra01 | Monoclonal Antibody to Interferon Gamma Inducible Protein 30 (IFI30) | WB; IHC; ICC; IP. |
| PAS051Ra01 | Polyclonal Antibody to Interferon Gamma Inducible Protein 30 (IFI30) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS051Ra01 | CLIA Kit for Interferon Gamma Inducible Protein 30 (IFI30) | CLIA assay for Antigen Detection |
| ELS051Ra01 | ELISA Kit for Interferon Gamma Inducible Protein 30 (IFI30) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Canis familiaris; Canine (Dog)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS051Ca01 | Recombinant Interferon Gamma Inducible Protein 30 (IFI30) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS051Ca01 | Monoclonal Antibody to Interferon Gamma Inducible Protein 30 (IFI30) | WB; IHC; ICC; IP. |
| PAS051Ca01 | Polyclonal Antibody to Interferon Gamma Inducible Protein 30 (IFI30) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS051Ca01 | CLIA Kit for Interferon Gamma Inducible Protein 30 (IFI30) | CLIA assay for Antigen Detection |
| ELS051Ca01 | ELISA Kit for Interferon Gamma Inducible Protein 30 (IFI30) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Sus scrofa; Porcine (Pig)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS051Po01 | Recombinant Interferon Gamma Inducible Protein 30 (IFI30) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS051Po01 | Monoclonal Antibody to Interferon Gamma Inducible Protein 30 (IFI30) | WB; IHC; ICC; IP. |
| PAS051Po01 | Polyclonal Antibody to Interferon Gamma Inducible Protein 30 (IFI30) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS051Po01 | CLIA Kit for Interferon Gamma Inducible Protein 30 (IFI30) | CLIA assay for Antigen Detection |
| ELS051Po01 | ELISA Kit for Interferon Gamma Inducible Protein 30 (IFI30) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Bos taurus; Bovine (Cattle)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS051Bo01 | Recombinant Interferon Gamma Inducible Protein 30 (IFI30) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS051Bo01 | Monoclonal Antibody to Interferon Gamma Inducible Protein 30 (IFI30) | WB; IHC; ICC; IP. |
| PAS051Bo01 | Polyclonal Antibody to Interferon Gamma Inducible Protein 30 (IFI30) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS051Bo01 | CLIA Kit for Interferon Gamma Inducible Protein 30 (IFI30) | CLIA assay for Antigen Detection |
| ELS051Bo01 | ELISA Kit for Interferon Gamma Inducible Protein 30 (IFI30) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Oryctolagus cuniculus (Rabbit)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS051Rb01 | Recombinant Interferon Gamma Inducible Protein 30 (IFI30) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS051Rb01 | Monoclonal Antibody to Interferon Gamma Inducible Protein 30 (IFI30) | WB; IHC; ICC; IP. |
| PAS051Rb01 | Polyclonal Antibody to Interferon Gamma Inducible Protein 30 (IFI30) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS051Rb01 | CLIA Kit for Interferon Gamma Inducible Protein 30 (IFI30) | CLIA assay for Antigen Detection |
| ELS051Rb01 | ELISA Kit for Interferon Gamma Inducible Protein 30 (IFI30) | Enzyme-linked immunosorbent assay for Antigen Detection |
Organism species: Rhesus monkey (Simian)
| PRODUCT TYPE | CATALOG NO. | PRODUCT NAME | APPLICATIONS |
|---|---|---|---|
| Proteins | RPS051Mo01 | Recombinant Interferon Gamma Inducible Protein 30 (IFI30) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | MAS051Mo01 | Monoclonal Antibody to Interferon Gamma Inducible Protein 30 (IFI30) | WB; IHC; ICC; IP. |
| PAS051Mo01 | Polyclonal Antibody to Interferon Gamma Inducible Protein 30 (IFI30) | WB; IHC; ICC; IF. | |
| Assay Kits | CLS051Mo01 | CLIA Kit for Interferon Gamma Inducible Protein 30 (IFI30) | CLIA assay for Antigen Detection |
| ELS051Mo01 | ELISA Kit for Interferon Gamma Inducible Protein 30 (IFI30) | Enzyme-linked immunosorbent assay for Antigen Detection |
Reference
"Molecular and biochemical characterization of a novel gamma-interferon-inducible protein."
J. Biol. Chem. 263:12036-12043(1988) [PubMed] [Europe PMC] [Abstract]
"Enzymatic reduction of disulfide bonds in lysosomes: characterization of a gamma-interferon-inducible lysosomal thiol reductase (GILT)."
Proc. Natl. Acad. Sci. U.S.A. 97:745-750(2000) [PubMed] [Europe PMC] [Abstract]
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
"The DNA sequence and biology of human chromosome 19."
Nature 428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
"Gamma-interferon-inducible lysosomal thiol reductase (GILT). Maturation, activity, and mechanism of action."
J. Biol. Chem. 275:25907-25914(2000) [PubMed] [Europe PMC] [Abstract]
"Initial characterization of the human central proteome."
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]