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Interleukin 23 Receptor (IL23R)

Interleukin 23 receptor is a subunit of the receptor for IL23A/IL23. This protein pairs with the receptor molecule IL12RB1/IL12Rbeta1, and both are required for IL23A signaling.
This protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand-dependent manner.Expressed by monocytes, Th1, Th0, NK and dendritic cells. Isoform 1 is specifically expressed in NK cells.Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins S048Hu01 Recombinant Interleukin 23 Receptor (IL23R) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Interleukin 23 Receptor (IL23R) Bioactivity
Antibodies MS048Hu21 Monoclonal Antibody to Interleukin 23 Receptor (IL23R) WB; IHC; ICC; IP.
PS048Hu01 Polyclonal Antibody to Interleukin 23 Receptor (IL23R) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) Flow Cytometry;ICC/IF
Assay Kits KES048Hu ELISA Kit for Interleukin 23 Receptor (IL23R) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Interleukin 23 Receptor (IL23R) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Interleukin 23 Receptor (IL23R) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Interleukin 23 Receptor (IL23R) Bioactivity
Antibodies NONE Monoclonal Antibody to Interleukin 23 Receptor (IL23R) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Interleukin 23 Receptor (IL23R) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Interleukin 23 Receptor (IL23R) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Interleukin 23 Receptor (IL23R) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins S048Ra01 Recombinant Interleukin 23 Receptor (IL23R) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Interleukin 23 Receptor (IL23R) Bioactivity
Antibodies MS048Ra21 Monoclonal Antibody to Interleukin 23 Receptor (IL23R) WB; IHC; ICC; IP.
PS048Ra01 Polyclonal Antibody to Interleukin 23 Receptor (IL23R) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) Flow Cytometry;ICC/IF
Assay Kits KES048Ra ELISA Kit for Interleukin 23 Receptor (IL23R) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Interleukin 23 Receptor (IL23R) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Interleukin 23 Receptor (IL23R) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Interleukin 23 Receptor (IL23R) Bioactivity
Antibodies NONE Monoclonal Antibody to Interleukin 23 Receptor (IL23R) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Interleukin 23 Receptor (IL23R) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Interleukin 23 Receptor (IL23R) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Interleukin 23 Receptor (IL23R) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Interleukin 23 Receptor (IL23R) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Interleukin 23 Receptor (IL23R) Bioactivity
Antibodies NONE Monoclonal Antibody to Interleukin 23 Receptor (IL23R) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Interleukin 23 Receptor (IL23R) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Interleukin 23 Receptor (IL23R) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Interleukin 23 Receptor (IL23R) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Interleukin 23 Receptor (IL23R) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Interleukin 23 Receptor (IL23R) Bioactivity
Antibodies NONE Monoclonal Antibody to Interleukin 23 Receptor (IL23R) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Interleukin 23 Receptor (IL23R) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Interleukin 23 Receptor (IL23R) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Interleukin 23 Receptor (IL23R) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Interleukin 23 Receptor (IL23R) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Interleukin 23 Receptor (IL23R) Bioactivity
Antibodies NONE Monoclonal Antibody to Interleukin 23 Receptor (IL23R) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Interleukin 23 Receptor (IL23R) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Interleukin 23 Receptor (IL23R) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Interleukin 23 Receptor (IL23R) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Interleukin 23 Receptor (IL23R) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Interleukin 23 Receptor (IL23R) Bioactivity
Antibodies NONE Monoclonal Antibody to Interleukin 23 Receptor (IL23R) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Interleukin 23 Receptor (IL23R) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Interleukin 23 Receptor (IL23R) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Interleukin 23 Receptor (IL23R) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Interleukin 23 Receptor (IL23R) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Interleukin 23 Receptor (IL23R) Bioactivity
Antibodies NONE Monoclonal Antibody to Interleukin 23 Receptor (IL23R) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Interleukin 23 Receptor (IL23R) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Interleukin 23 Receptor (IL23R) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Interleukin 23 Receptor (IL23R) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Interleukin 23 Receptor (IL23R) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Interleukin 23 Receptor (IL23R) Bioactivity
Antibodies NONE Monoclonal Antibody to Interleukin 23 Receptor (IL23R) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Interleukin 23 Receptor (IL23R) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Interleukin 23 Receptor (IL23R) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Interleukin 23 Receptor (IL23R) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Interleukin 23 Receptor (IL23R) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Interleukin 23 Receptor (IL23R) Bioactivity
Antibodies NONE Monoclonal Antibody to Interleukin 23 Receptor (IL23R) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Interleukin 23 Receptor (IL23R) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Interleukin 23 Receptor (IL23R) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Interleukin 23 Receptor (IL23R) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Interleukin 23 Receptor (IL23R) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Interleukin 23 Receptor (IL23R) Bioactivity
Antibodies NONE Monoclonal Antibody to Interleukin 23 Receptor (IL23R) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Interleukin 23 Receptor (IL23R) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Interleukin 23 Receptor (IL23R) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Interleukin 23 Receptor (IL23R) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Interleukin 23 Receptor (IL23R) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Interleukin 23 Receptor (IL23R) Bioactivity
Antibodies NONE Monoclonal Antibody to Interleukin 23 Receptor (IL23R) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Interleukin 23 Receptor (IL23R) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Interleukin 23 Receptor (IL23R) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Interleukin 23 Receptor (IL23R) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Interleukin 23 Receptor (IL23R) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Interleukin 23 Receptor (IL23R) Bioactivity
Antibodies NONE Monoclonal Antibody to Interleukin 23 Receptor (IL23R) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Interleukin 23 Receptor (IL23R) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Interleukin 23 Receptor (IL23R) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Interleukin 23 Receptor (IL23R) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Interleukin 23 Receptor (IL23R) CLIA assay for Antigen Detection

Reference

"A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rbeta1 and a novel cytokine receptor subunit, IL-23R."
J. Immunol. 168:5699-5708(2002) [PubMed] [Europe PMC] [Abstract]

"Identification and expression analysis of alternatively spliced isoforms of human interleukin-23 receptor gene in normal lymphoid cells and selected tumor cells."
Immunogenetics 57:934-943(2006) [PubMed] [Europe PMC] [Abstract]

"The DNA sequence and biological annotation of human chromosome 1."
Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"A genome-wide association study identifies IL23R as an inflammatory bowel disease gene."
Science 314:1461-1463(2006) [PubMed] [Europe PMC] [Abstract]

"Sequence variants in the genes for the interleukin-23 receptor (IL23R) and its ligand (IL12B) confer protection against psoriasis."
Hum. Genet. 122:201-206(2007) [PubMed] [Europe PMC] [Abstract]

"Genome-wide association study for Crohn's disease in the Quebec founder population identifies multiple validated disease loci."
Proc. Natl. Acad. Sci. U.S.A. 104:14747-14752(2007) [PubMed] [Europe PMC] [Abstract]

"Genetic variants of the IL-23R pathway: association with psoriatic arthritis and psoriasis vulgaris, but no specific risk factor for arthritis."
J. Invest. Dermatol. 129:355-358(2009) [PubMed] [Europe PMC] [Abstract]

"Glycosylation analysis of interleukin-23 receptor: elucidation of glycosylation sites and characterization of attached glycan structures."
J. Mass Spectrom. 45:1416-1425(2010) [PubMed] [Europe PMC] [Abstract]