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Diacylglycerol Kinase Epsilon (DGKe)

DAGK5; DGK; Diglyceride kinase epsilon

Diacylglycerol kinases are thought to be involved mainly in the regeneration of phosphatidylinositol (PI) from diacylglycerol in the PI-cycle during cell signal transduction. When expressed in mammalian cells, DGK-epsilon shows specificity for arachidonyl-containing diacylglycerol. DGK-epsilon is expressed predominantly in testis.A product with a novel sequence was identified and used to clone a 2.6-kb cDNA from an endothelial cell library. They named this gene DGK-epsilon. The cDNA encoded a 567-amino acid polypeptide with a predicted molecular weight of 64 kD. The catalytic region of DGK-epsilon shares 38 to 42% sequence identity with other DGKs, including DGK-alpha and DGK-delta. When expressed in mammalian cells, DGK-epsilon showed specificity for arachidonyl-containing diacylglycerol.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Diacylglycerol Kinase Epsilon (DGKe) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Diacylglycerol Kinase Epsilon (DGKe) Bioactivity
Antibodies NONE Monoclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) WB; IHC; ICC; IP.
PR964Hu01 Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Diacylglycerol Kinase Epsilon (DGKe) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Diacylglycerol Kinase Epsilon (DGKe) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Diacylglycerol Kinase Epsilon (DGKe) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Diacylglycerol Kinase Epsilon (DGKe) Bioactivity
Antibodies NONE Monoclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Diacylglycerol Kinase Epsilon (DGKe) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Diacylglycerol Kinase Epsilon (DGKe) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Diacylglycerol Kinase Epsilon (DGKe) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Diacylglycerol Kinase Epsilon (DGKe) Bioactivity
Antibodies NONE Monoclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Diacylglycerol Kinase Epsilon (DGKe) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Diacylglycerol Kinase Epsilon (DGKe) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Diacylglycerol Kinase Epsilon (DGKe) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Diacylglycerol Kinase Epsilon (DGKe) Bioactivity
Antibodies NONE Monoclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Diacylglycerol Kinase Epsilon (DGKe) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Diacylglycerol Kinase Epsilon (DGKe) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Diacylglycerol Kinase Epsilon (DGKe) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Diacylglycerol Kinase Epsilon (DGKe) Bioactivity
Antibodies NONE Monoclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Diacylglycerol Kinase Epsilon (DGKe) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Diacylglycerol Kinase Epsilon (DGKe) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Diacylglycerol Kinase Epsilon (DGKe) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Diacylglycerol Kinase Epsilon (DGKe) Bioactivity
Antibodies NONE Monoclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Diacylglycerol Kinase Epsilon (DGKe) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Diacylglycerol Kinase Epsilon (DGKe) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Diacylglycerol Kinase Epsilon (DGKe) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Diacylglycerol Kinase Epsilon (DGKe) Bioactivity
Antibodies NONE Monoclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Diacylglycerol Kinase Epsilon (DGKe) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Diacylglycerol Kinase Epsilon (DGKe) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Diacylglycerol Kinase Epsilon (DGKe) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Diacylglycerol Kinase Epsilon (DGKe) Bioactivity
Antibodies NONE Monoclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Diacylglycerol Kinase Epsilon (DGKe) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Diacylglycerol Kinase Epsilon (DGKe) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Diacylglycerol Kinase Epsilon (DGKe) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Diacylglycerol Kinase Epsilon (DGKe) Bioactivity
Antibodies NONE Monoclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Diacylglycerol Kinase Epsilon (DGKe) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Diacylglycerol Kinase Epsilon (DGKe) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Diacylglycerol Kinase Epsilon (DGKe) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Diacylglycerol Kinase Epsilon (DGKe) Bioactivity
Antibodies NONE Monoclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Diacylglycerol Kinase Epsilon (DGKe) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Diacylglycerol Kinase Epsilon (DGKe) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Diacylglycerol Kinase Epsilon (DGKe) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Diacylglycerol Kinase Epsilon (DGKe) Bioactivity
Antibodies NONE Monoclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Diacylglycerol Kinase Epsilon (DGKe) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Diacylglycerol Kinase Epsilon (DGKe) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Diacylglycerol Kinase Epsilon (DGKe) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Diacylglycerol Kinase Epsilon (DGKe) Bioactivity
Antibodies NONE Monoclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Diacylglycerol Kinase Epsilon (DGKe) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Diacylglycerol Kinase Epsilon (DGKe) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Diacylglycerol Kinase Epsilon (DGKe) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Diacylglycerol Kinase Epsilon (DGKe) Bioactivity
Antibodies NONE Monoclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Diacylglycerol Kinase Epsilon (DGKe) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Diacylglycerol Kinase Epsilon (DGKe) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Diacylglycerol Kinase Epsilon (DGKe) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Diacylglycerol Kinase Epsilon (DGKe) Bioactivity
Antibodies NONE Monoclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Diacylglycerol Kinase Epsilon (DGKe) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Diacylglycerol Kinase Epsilon (DGKe) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Diacylglycerol Kinase Epsilon (DGKe) CLIA assay for Antigen Detection

Reference

"Molecular cloning of a novel human diacylglycerol kinase highly selective for arachidonate-containing substrates."
J. Biol. Chem. 271:10237-10241(1996) [PubMed] [Europe PMC] [Abstract]

"DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage."
Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Characterization of the human diacylglycerol kinase epsilon gene and its assessment as a candidate for inherited retinitis pigmentosa."
Gene 239:185-192(1999) [PubMed] [Europe PMC] [Abstract]

"DGKE variants cause a glomerular microangiopathy that mimics membranoproliferative GN."
J. Am. Soc. Nephrol. 24:377-384(2013) [PubMed] [Europe PMC] [Abstract]

"Recessive mutations in DGKE cause atypical hemolytic-uremic syndrome."
Nat. Genet. 45:531-536(2013) [PubMed] [Europe PMC] [Abstract]

"The consensus coding sequences of human breast and colorectal cancers."
Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]