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Diacylglycerol Kinase Zeta (DGKz)

DAGK5; DAGK6; DGK-ZETA; hDGKzeta; Diglyceride kinase zeta

Diacylglycerol kinase zeta is an enzyme belongs to the eukaryotic diacylglycerol kinase family. It may attenuate protein kinase C activity by regulating diacylglycerol levels in intracellular signaling cascade and signal transduction. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified.
Human DGK-zeta contains 2 zinc fingers, an ATP-binding site, and 4 ankyrin repeats near the C terminus. A unique feature, as compared with other DGKs, is the presence of a sequence homologous to the MARCKS phosphorylation site domain. Northern blot analysis of multiple tissues showed that DGK-zeta is expressed at highest levels in brain and muscle.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Diacylglycerol Kinase Zeta (DGKz) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Diacylglycerol Kinase Zeta (DGKz) Bioactivity
Antibodies NONE Monoclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) WB; IHC; ICC; IP.
PR958Hu01 Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Diacylglycerol Kinase Zeta (DGKz) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Diacylglycerol Kinase Zeta (DGKz) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins R958Mu01 Recombinant Diacylglycerol Kinase Zeta (DGKz) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Diacylglycerol Kinase Zeta (DGKz) Bioactivity
Antibodies NONE Monoclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) WB; IHC; ICC; IP.
PR958Mu01 Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Diacylglycerol Kinase Zeta (DGKz) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Diacylglycerol Kinase Zeta (DGKz) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Diacylglycerol Kinase Zeta (DGKz) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Diacylglycerol Kinase Zeta (DGKz) Bioactivity
Antibodies NONE Monoclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Diacylglycerol Kinase Zeta (DGKz) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Diacylglycerol Kinase Zeta (DGKz) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Diacylglycerol Kinase Zeta (DGKz) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Diacylglycerol Kinase Zeta (DGKz) Bioactivity
Antibodies NONE Monoclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Diacylglycerol Kinase Zeta (DGKz) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Diacylglycerol Kinase Zeta (DGKz) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Diacylglycerol Kinase Zeta (DGKz) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Diacylglycerol Kinase Zeta (DGKz) Bioactivity
Antibodies NONE Monoclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Diacylglycerol Kinase Zeta (DGKz) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Diacylglycerol Kinase Zeta (DGKz) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Diacylglycerol Kinase Zeta (DGKz) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Diacylglycerol Kinase Zeta (DGKz) Bioactivity
Antibodies NONE Monoclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Diacylglycerol Kinase Zeta (DGKz) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Diacylglycerol Kinase Zeta (DGKz) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Diacylglycerol Kinase Zeta (DGKz) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Diacylglycerol Kinase Zeta (DGKz) Bioactivity
Antibodies NONE Monoclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Diacylglycerol Kinase Zeta (DGKz) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Diacylglycerol Kinase Zeta (DGKz) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Diacylglycerol Kinase Zeta (DGKz) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Diacylglycerol Kinase Zeta (DGKz) Bioactivity
Antibodies NONE Monoclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Diacylglycerol Kinase Zeta (DGKz) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Diacylglycerol Kinase Zeta (DGKz) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Diacylglycerol Kinase Zeta (DGKz) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Diacylglycerol Kinase Zeta (DGKz) Bioactivity
Antibodies NONE Monoclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Diacylglycerol Kinase Zeta (DGKz) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Diacylglycerol Kinase Zeta (DGKz) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Diacylglycerol Kinase Zeta (DGKz) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Diacylglycerol Kinase Zeta (DGKz) Bioactivity
Antibodies NONE Monoclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Diacylglycerol Kinase Zeta (DGKz) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Diacylglycerol Kinase Zeta (DGKz) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Diacylglycerol Kinase Zeta (DGKz) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Diacylglycerol Kinase Zeta (DGKz) Bioactivity
Antibodies NONE Monoclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Diacylglycerol Kinase Zeta (DGKz) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Diacylglycerol Kinase Zeta (DGKz) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Diacylglycerol Kinase Zeta (DGKz) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Diacylglycerol Kinase Zeta (DGKz) Bioactivity
Antibodies NONE Monoclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Diacylglycerol Kinase Zeta (DGKz) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Diacylglycerol Kinase Zeta (DGKz) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Diacylglycerol Kinase Zeta (DGKz) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Diacylglycerol Kinase Zeta (DGKz) Bioactivity
Antibodies NONE Monoclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Diacylglycerol Kinase Zeta (DGKz) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Diacylglycerol Kinase Zeta (DGKz) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Diacylglycerol Kinase Zeta (DGKz) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Diacylglycerol Kinase Zeta (DGKz) Bioactivity
Antibodies NONE Monoclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Diacylglycerol Kinase Zeta (DGKz) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Diacylglycerol Kinase Zeta (DGKz) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Diacylglycerol Kinase Zeta (DGKz) CLIA assay for Antigen Detection

Reference

"Molecular cloning and characterization of a novel human diacylglycerol kinase zeta."
J. Biol. Chem. 271:10230-10236(1996) [PubMed] [Europe PMC] [Abstract]

"Alternative splicing of the human diacylglycerol kinase zeta gene in muscle."
Proc. Natl. Acad. Sci. U.S.A. 94:5519-5524(1997) [PubMed] [Europe PMC] [Abstract]

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"Human chromosome 11 DNA sequence and analysis including novel gene identification."
Nature 440:497-500(2006) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Protein kinase C regulates the nuclear localization of diacylglycerol kinase-zeta."
Nature 394:697-700(1998) [PubMed] [Europe PMC] [Abstract]

"Interaction of gamma 1-syntrophin with diacylglycerol kinase-zeta. Regulation of nuclear localization by PDZ interactions."
J. Biol. Chem. 276:26526-26533(2001) [PubMed] [Europe PMC] [Abstract]

"Diacylglycerol kinase zeta regulates Ras activation by a novel mechanism."
J. Cell Biol. 152:1135-1143(2001) [PubMed] [Europe PMC] [Abstract]

"Proteomics identification of sorting nexin 27 as a diacylglycerol kinase zeta-associated protein: new diacylglycerol kinase roles in endocytic recycling."
Mol. Cell. Proteomics 6:1073-1087(2007) [PubMed] [Europe PMC] [Abstract]

"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]