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C4 Binding Protein Alpha (C4BPa)

C4BP-a; PRP; C4BP; Complement Component 4 Binding Protein,Alpha; Proline-rich protein

C4b-binding protein is involved in regulation of the complement system. It is a multimeric protein comprising 7 identical alpha chains, encoded by C4BPA, and a single beta chain, encoded by C4BPB. The alpha and beta chains have molecular masses of 70 and 45 kD, respectively. Both subunits belong to a superfamily of proteins composed predominantly of tandemly arranged short consensus repeats (SCR) of approximately 60 amino acids in length (Aso et al., 1991).
Brodeur et al. (2003) identified a 23-kD protein that bound CD40 as C4BP-alpha. Flow cytometric analysis demonstrated binding of C4BP to human B-cell lines expressing CD40, but not to cells from CD40-deficient patients.Aso et al. (1991) found that the C4BPA gene comprises 12 exons and spans about 40 kb.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins R940Hu01 Recombinant C4 Binding Protein Alpha (C4BPa) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native C4 Binding Protein Alpha (C4BPa) Bioactivity
Antibodies MR940Hu22 Monoclonal Antibody to C4 Binding Protein Alpha (C4BPa) WB; IHC; ICC; IP.
PR940Hu01 Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) WB; IHC; ICC; IF.
LR940Hu71 Biotin Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) IHC, WB
NONE HRP Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) Flow Cytometry;ICC/IF
Assay Kits KER940Hu ELISA Kit for C4 Binding Protein Alpha (C4BPa) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for C4 Binding Protein Alpha (C4BPa) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins R940Mu02 Recombinant C4 Binding Protein Alpha (C4BPa) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native C4 Binding Protein Alpha (C4BPa) Bioactivity
Antibodies NONE Monoclonal Antibody to C4 Binding Protein Alpha (C4BPa) WB; IHC; ICC; IP.
PR940Mu01 Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) IHC, WB
NONE HRP Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for C4 Binding Protein Alpha (C4BPa) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for C4 Binding Protein Alpha (C4BPa) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins R940Ra01 Recombinant C4 Binding Protein Alpha (C4BPa) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native C4 Binding Protein Alpha (C4BPa) Bioactivity
Antibodies MR940Ra21 Monoclonal Antibody to C4 Binding Protein Alpha (C4BPa) WB; IHC; ICC; IP.
PR940Ra01 Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) IHC, WB
NONE HRP Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) Flow Cytometry;ICC/IF
Assay Kits KER940Ra ELISA Kit for C4 Binding Protein Alpha (C4BPa) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for C4 Binding Protein Alpha (C4BPa) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant C4 Binding Protein Alpha (C4BPa) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native C4 Binding Protein Alpha (C4BPa) Bioactivity
Antibodies NONE Monoclonal Antibody to C4 Binding Protein Alpha (C4BPa) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) IHC, WB
NONE HRP Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for C4 Binding Protein Alpha (C4BPa) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for C4 Binding Protein Alpha (C4BPa) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant C4 Binding Protein Alpha (C4BPa) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native C4 Binding Protein Alpha (C4BPa) Bioactivity
Antibodies NONE Monoclonal Antibody to C4 Binding Protein Alpha (C4BPa) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) IHC, WB
NONE HRP Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for C4 Binding Protein Alpha (C4BPa) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for C4 Binding Protein Alpha (C4BPa) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant C4 Binding Protein Alpha (C4BPa) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native C4 Binding Protein Alpha (C4BPa) Bioactivity
Antibodies NONE Monoclonal Antibody to C4 Binding Protein Alpha (C4BPa) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) IHC, WB
NONE HRP Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for C4 Binding Protein Alpha (C4BPa) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for C4 Binding Protein Alpha (C4BPa) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant C4 Binding Protein Alpha (C4BPa) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native C4 Binding Protein Alpha (C4BPa) Bioactivity
Antibodies NONE Monoclonal Antibody to C4 Binding Protein Alpha (C4BPa) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) IHC, WB
NONE HRP Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for C4 Binding Protein Alpha (C4BPa) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for C4 Binding Protein Alpha (C4BPa) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant C4 Binding Protein Alpha (C4BPa) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native C4 Binding Protein Alpha (C4BPa) Bioactivity
Antibodies NONE Monoclonal Antibody to C4 Binding Protein Alpha (C4BPa) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) IHC, WB
NONE HRP Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for C4 Binding Protein Alpha (C4BPa) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for C4 Binding Protein Alpha (C4BPa) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant C4 Binding Protein Alpha (C4BPa) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native C4 Binding Protein Alpha (C4BPa) Bioactivity
Antibodies NONE Monoclonal Antibody to C4 Binding Protein Alpha (C4BPa) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) IHC, WB
NONE HRP Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for C4 Binding Protein Alpha (C4BPa) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for C4 Binding Protein Alpha (C4BPa) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant C4 Binding Protein Alpha (C4BPa) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native C4 Binding Protein Alpha (C4BPa) Bioactivity
Antibodies NONE Monoclonal Antibody to C4 Binding Protein Alpha (C4BPa) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) IHC, WB
NONE HRP Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for C4 Binding Protein Alpha (C4BPa) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for C4 Binding Protein Alpha (C4BPa) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant C4 Binding Protein Alpha (C4BPa) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native C4 Binding Protein Alpha (C4BPa) Bioactivity
Antibodies NONE Monoclonal Antibody to C4 Binding Protein Alpha (C4BPa) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) IHC, WB
NONE HRP Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for C4 Binding Protein Alpha (C4BPa) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for C4 Binding Protein Alpha (C4BPa) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant C4 Binding Protein Alpha (C4BPa) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native C4 Binding Protein Alpha (C4BPa) Bioactivity
Antibodies NONE Monoclonal Antibody to C4 Binding Protein Alpha (C4BPa) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) IHC, WB
NONE HRP Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for C4 Binding Protein Alpha (C4BPa) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for C4 Binding Protein Alpha (C4BPa) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant C4 Binding Protein Alpha (C4BPa) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native C4 Binding Protein Alpha (C4BPa) Bioactivity
Antibodies NONE Monoclonal Antibody to C4 Binding Protein Alpha (C4BPa) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) IHC, WB
NONE HRP Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for C4 Binding Protein Alpha (C4BPa) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for C4 Binding Protein Alpha (C4BPa) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant C4 Binding Protein Alpha (C4BPa) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native C4 Binding Protein Alpha (C4BPa) Bioactivity
Antibodies NONE Monoclonal Antibody to C4 Binding Protein Alpha (C4BPa) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) IHC, WB
NONE HRP Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to C4 Binding Protein Alpha (C4BPa) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for C4 Binding Protein Alpha (C4BPa) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for C4 Binding Protein Alpha (C4BPa) CLIA assay for Antigen Detection

Reference

"Molecular cloning of the cDNA coding for proline-rich protein (PRP): identity of PRP as C4b-binding protein."
Biochem. Biophys. Res. Commun. 165:138-144(1989) [PubMed] [Europe PMC] [Abstract]

"Genomic organization of the alpha chain of the human C4b-binding protein gene."
Biochem. Biophys. Res. Commun. 174:222-227(1991) [PubMed] [Europe PMC] [Abstract]

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Derivation of the sequence of the signal peptide in human C4b-binding protein and interspecies cross-hybridisation of the C4bp cDNA sequence."
FEBS Lett. 232:328-332(1988) [PubMed] [Europe PMC] [Abstract]

"Studies on the structure of the human C4b-binding protein gene."
FEBS Lett. 204:77-81(1986) [PubMed] [Europe PMC] [Abstract]

"Molecular cloning and characterization of the cDNA coding for C4b-binding protein, a regulatory protein of the classical pathway of the human complement system."
Biochem. J. 230:133-141(1985) [PubMed] [Europe PMC] [Abstract]

"Amino acid sequence studies of human C4b-binding protein: N-terminal sequence analysis and alignment of the fragments produced by limited proteolysis with chymotrypsin and the peptides produced by cyanogen bromide treatment."
Mol. Immunol. 22:427-435(1985) [PubMed] [Europe PMC] [Abstract]

"Screening for N-glycosylated proteins by liquid chromatography mass spectrometry."
Proteomics 4:454-465(2004) [PubMed] [Europe PMC] [Abstract]

"Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."
J. Proteome Res. 4:2070-2080(2005) [PubMed] [Europe PMC] [Abstract]

"Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
J. Proteome Res. 8:651-661(2009) [PubMed] [Europe PMC] [Abstract]

"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]

"Visualization of human C4b-binding protein and its complexes with vitamin K-dependent protein S and complement protein C4b."
Proc. Natl. Acad. Sci. U.S.A. 80:3461-3465(1983) [PubMed] [Europe PMC] [Abstract]

"Human C4b-binding protein, structural basis for interaction with streptococcal M protein, a major bacterial virulence factor."
J. Biol. Chem. 281:3690-3697(2006) [PubMed] [Europe PMC] [Abstract]