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Sorting Nexin 17 (SNX17)

Sorting nexin-17 is a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members, but contains a B41 domain.
This protein interacts with the cytoplasmic domain of P-selectin, and may function in the intracellular trafficking of P-selectin.the deduced 470-amino acid SNX17 protein contains a PX domain that shares 28% sequence identity with the PX domain of sorting nexin-1 as well as a B41 (FERM) domain. Expression of a GFP-SNX17 fusion protein demonstrated localization of SNX17 in the cytosol and on membranes.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins R925Hu01 Recombinant Sorting Nexin 17 (SNX17) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Sorting Nexin 17 (SNX17) Bioactivity
Antibodies MR925Hu21 Monoclonal Antibody to Sorting Nexin 17 (SNX17) WB; IHC; ICC; IP.
PR925Hu01 Polyclonal Antibody to Sorting Nexin 17 (SNX17) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) Flow Cytometry;ICC/IF
Assay Kits KER925Hu ELISA Kit for Sorting Nexin 17 (SNX17) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Sorting Nexin 17 (SNX17) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Sorting Nexin 17 (SNX17) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Sorting Nexin 17 (SNX17) Bioactivity
Antibodies NONE Monoclonal Antibody to Sorting Nexin 17 (SNX17) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Sorting Nexin 17 (SNX17) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Sorting Nexin 17 (SNX17) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Sorting Nexin 17 (SNX17) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Sorting Nexin 17 (SNX17) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Sorting Nexin 17 (SNX17) Bioactivity
Antibodies NONE Monoclonal Antibody to Sorting Nexin 17 (SNX17) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Sorting Nexin 17 (SNX17) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Sorting Nexin 17 (SNX17) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Sorting Nexin 17 (SNX17) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Sorting Nexin 17 (SNX17) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Sorting Nexin 17 (SNX17) Bioactivity
Antibodies NONE Monoclonal Antibody to Sorting Nexin 17 (SNX17) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Sorting Nexin 17 (SNX17) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Sorting Nexin 17 (SNX17) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Sorting Nexin 17 (SNX17) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Sorting Nexin 17 (SNX17) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Sorting Nexin 17 (SNX17) Bioactivity
Antibodies NONE Monoclonal Antibody to Sorting Nexin 17 (SNX17) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Sorting Nexin 17 (SNX17) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Sorting Nexin 17 (SNX17) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Sorting Nexin 17 (SNX17) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Sorting Nexin 17 (SNX17) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Sorting Nexin 17 (SNX17) Bioactivity
Antibodies NONE Monoclonal Antibody to Sorting Nexin 17 (SNX17) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Sorting Nexin 17 (SNX17) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Sorting Nexin 17 (SNX17) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Sorting Nexin 17 (SNX17) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Sorting Nexin 17 (SNX17) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Sorting Nexin 17 (SNX17) Bioactivity
Antibodies NONE Monoclonal Antibody to Sorting Nexin 17 (SNX17) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Sorting Nexin 17 (SNX17) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Sorting Nexin 17 (SNX17) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Sorting Nexin 17 (SNX17) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Sorting Nexin 17 (SNX17) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Sorting Nexin 17 (SNX17) Bioactivity
Antibodies NONE Monoclonal Antibody to Sorting Nexin 17 (SNX17) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Sorting Nexin 17 (SNX17) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Sorting Nexin 17 (SNX17) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Sorting Nexin 17 (SNX17) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Sorting Nexin 17 (SNX17) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Sorting Nexin 17 (SNX17) Bioactivity
Antibodies NONE Monoclonal Antibody to Sorting Nexin 17 (SNX17) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Sorting Nexin 17 (SNX17) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Sorting Nexin 17 (SNX17) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Sorting Nexin 17 (SNX17) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Sorting Nexin 17 (SNX17) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Sorting Nexin 17 (SNX17) Bioactivity
Antibodies NONE Monoclonal Antibody to Sorting Nexin 17 (SNX17) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Sorting Nexin 17 (SNX17) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Sorting Nexin 17 (SNX17) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Sorting Nexin 17 (SNX17) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Sorting Nexin 17 (SNX17) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Sorting Nexin 17 (SNX17) Bioactivity
Antibodies NONE Monoclonal Antibody to Sorting Nexin 17 (SNX17) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Sorting Nexin 17 (SNX17) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Sorting Nexin 17 (SNX17) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Sorting Nexin 17 (SNX17) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Sorting Nexin 17 (SNX17) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Sorting Nexin 17 (SNX17) Bioactivity
Antibodies NONE Monoclonal Antibody to Sorting Nexin 17 (SNX17) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Sorting Nexin 17 (SNX17) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Sorting Nexin 17 (SNX17) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Sorting Nexin 17 (SNX17) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Sorting Nexin 17 (SNX17) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Sorting Nexin 17 (SNX17) Bioactivity
Antibodies NONE Monoclonal Antibody to Sorting Nexin 17 (SNX17) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Sorting Nexin 17 (SNX17) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Sorting Nexin 17 (SNX17) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Sorting Nexin 17 (SNX17) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Sorting Nexin 17 (SNX17) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Sorting Nexin 17 (SNX17) Bioactivity
Antibodies NONE Monoclonal Antibody to Sorting Nexin 17 (SNX17) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Sorting Nexin 17 (SNX17) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Sorting Nexin 17 (SNX17) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Sorting Nexin 17 (SNX17) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Sorting Nexin 17 (SNX17) CLIA assay for Antigen Detection

Reference

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Nat. Biotechnol. 21:566-569(2003) [PubMed] [Europe PMC] [Abstract]

"A new member of the sorting nexin family interacts with the C-terminus of P-selectin."
Biochem. Biophys. Res. Commun. 281:1045-1050(2001) [PubMed] [Europe PMC] [Abstract]

"Sorting motifs in the intracellular domain of the low density lipoprotein receptor interact with a novel domain of sorting nexin-17."
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"Sorting nexin 17 accelerates internalization yet retards degradation of P-selectin."
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"Functions of sorting nexin 17 domains and recognition motif for P-selectin trafficking."
J. Mol. Biol. 347:813-825(2005) [PubMed] [Europe PMC] [Abstract]

"Sorting nexin 17, a non-self-assembling and a PtdIns(3)P high class affinity protein, interacts with the cerebral cavernous malformation related protein KRIT1."
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"A quantitative atlas of mitotic phosphorylation."
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]

"Polarized traffic of LRP1 involves AP1B and SNX17 operating on Y-dependent sorting motifs in different pathways."
Mol. Biol. Cell 20:481-497(2009) [PubMed] [Europe PMC] [Abstract]

"Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
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"Initial characterization of the human central proteome."
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"System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
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"SNX17 protects integrins from degradation by sorting between lysosomal and recycling pathways."
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"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]

"Crystal structure of the PX domain of sorting nexin-17 (SNX17)."
Submitted (JAN-2009) to the PDB data bank

"Phox homology band 4.1/ezrin/radixin/moesin-like proteins function as molecular scaffolds that interact with cargo receptors and Ras GTPases."
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