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Replication Factor C5 (RFC5)

RFC36; Activator 1 36 kDa subunit; Activator 1 subunit 5; Replication factor C 36 kDa subunit

The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD.
RFC5 encodes the 36 kD subunit. This subunit can interact with the C-terminal region of PCNA. It forms a core complex with the 38 and 40 kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins R725Hu01 Recombinant Replication Factor C5 (RFC5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Replication Factor C5 (RFC5) Bioactivity
Antibodies NONE Monoclonal Antibody to Replication Factor C5 (RFC5) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Replication Factor C5 (RFC5) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Replication Factor C5 (RFC5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Replication Factor C5 (RFC5) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins R725Mu01 Recombinant Replication Factor C5 (RFC5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Replication Factor C5 (RFC5) Bioactivity
Antibodies NONE Monoclonal Antibody to Replication Factor C5 (RFC5) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Replication Factor C5 (RFC5) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Replication Factor C5 (RFC5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Replication Factor C5 (RFC5) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Replication Factor C5 (RFC5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Replication Factor C5 (RFC5) Bioactivity
Antibodies NONE Monoclonal Antibody to Replication Factor C5 (RFC5) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Replication Factor C5 (RFC5) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Replication Factor C5 (RFC5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Replication Factor C5 (RFC5) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Replication Factor C5 (RFC5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Replication Factor C5 (RFC5) Bioactivity
Antibodies NONE Monoclonal Antibody to Replication Factor C5 (RFC5) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Replication Factor C5 (RFC5) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Replication Factor C5 (RFC5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Replication Factor C5 (RFC5) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Replication Factor C5 (RFC5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Replication Factor C5 (RFC5) Bioactivity
Antibodies NONE Monoclonal Antibody to Replication Factor C5 (RFC5) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Replication Factor C5 (RFC5) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Replication Factor C5 (RFC5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Replication Factor C5 (RFC5) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Replication Factor C5 (RFC5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Replication Factor C5 (RFC5) Bioactivity
Antibodies NONE Monoclonal Antibody to Replication Factor C5 (RFC5) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Replication Factor C5 (RFC5) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Replication Factor C5 (RFC5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Replication Factor C5 (RFC5) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Replication Factor C5 (RFC5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Replication Factor C5 (RFC5) Bioactivity
Antibodies NONE Monoclonal Antibody to Replication Factor C5 (RFC5) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Replication Factor C5 (RFC5) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Replication Factor C5 (RFC5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Replication Factor C5 (RFC5) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Replication Factor C5 (RFC5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Replication Factor C5 (RFC5) Bioactivity
Antibodies NONE Monoclonal Antibody to Replication Factor C5 (RFC5) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Replication Factor C5 (RFC5) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Replication Factor C5 (RFC5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Replication Factor C5 (RFC5) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Replication Factor C5 (RFC5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Replication Factor C5 (RFC5) Bioactivity
Antibodies NONE Monoclonal Antibody to Replication Factor C5 (RFC5) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Replication Factor C5 (RFC5) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Replication Factor C5 (RFC5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Replication Factor C5 (RFC5) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Replication Factor C5 (RFC5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Replication Factor C5 (RFC5) Bioactivity
Antibodies NONE Monoclonal Antibody to Replication Factor C5 (RFC5) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Replication Factor C5 (RFC5) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Replication Factor C5 (RFC5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Replication Factor C5 (RFC5) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Replication Factor C5 (RFC5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Replication Factor C5 (RFC5) Bioactivity
Antibodies NONE Monoclonal Antibody to Replication Factor C5 (RFC5) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Replication Factor C5 (RFC5) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Replication Factor C5 (RFC5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Replication Factor C5 (RFC5) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Replication Factor C5 (RFC5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Replication Factor C5 (RFC5) Bioactivity
Antibodies NONE Monoclonal Antibody to Replication Factor C5 (RFC5) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Replication Factor C5 (RFC5) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Replication Factor C5 (RFC5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Replication Factor C5 (RFC5) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Replication Factor C5 (RFC5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Replication Factor C5 (RFC5) Bioactivity
Antibodies NONE Monoclonal Antibody to Replication Factor C5 (RFC5) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Replication Factor C5 (RFC5) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Replication Factor C5 (RFC5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Replication Factor C5 (RFC5) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Replication Factor C5 (RFC5) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Replication Factor C5 (RFC5) Bioactivity
Antibodies NONE Monoclonal Antibody to Replication Factor C5 (RFC5) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Replication Factor C5 (RFC5) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Replication Factor C5 (RFC5) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Replication Factor C5 (RFC5) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Replication Factor C5 (RFC5) CLIA assay for Antigen Detection

Reference

"Homology in accessory proteins of replicative polymerases -- E. coli to humans."
Nucleic Acids Res. 21:1-3(1993) [PubMed] [Europe PMC] [Abstract]

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

"The finished DNA sequence of human chromosome 12."
Nature 440:346-351(2006) [PubMed] [Europe PMC] [Abstract]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

"Replication factor C interacts with the C-terminal side of proliferating cell nuclear antigen."
J. Biol. Chem. 272:1769-1776(1997) [PubMed] [Europe PMC] [Abstract]

"Purification and characterization of human DNA damage checkpoint Rad complexes."
Proc. Natl. Acad. Sci. U.S.A. 98:11236-11241(2001) [PubMed] [Europe PMC] [Abstract]

"Initial characterization of the human central proteome."
BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

"N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."
Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]

"An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]