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Replication Factor C4 (RFC4)
Replication Factor C4 (RFC4)
RFC37; Activator 1 37 kDa subunit; Activator 1 subunit 4; Replication factor C 37 kDa subunit
The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD.
RFC4 encodes the 37 kD subunit. This subunit forms a core complex with the 36 and 40 kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system. Alternatively spliced transcript variants encoding the same protein have been reported. This subunit may be involved in the elongation of the multiprimed DNA template.
Organism species: Homo sapiens (Human)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
R724Hu01
Recombinant Replication Factor C4 (RFC4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Replication Factor C4 (RFC4) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Replication Factor C4 (RFC4) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Replication Factor C4 (RFC4) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Replication Factor C4 (RFC4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Replication Factor C4 (RFC4) CLIA assay for Antigen Detection
Organism species: Mus musculus (Mouse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
R724Mu01
Recombinant Replication Factor C4 (RFC4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Replication Factor C4 (RFC4) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Replication Factor C4 (RFC4) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Replication Factor C4 (RFC4) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Replication Factor C4 (RFC4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Replication Factor C4 (RFC4) CLIA assay for Antigen Detection
Organism species: Rattus norvegicus (Rat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Replication Factor C4 (RFC4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Replication Factor C4 (RFC4) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Replication Factor C4 (RFC4) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Replication Factor C4 (RFC4) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Replication Factor C4 (RFC4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Replication Factor C4 (RFC4) CLIA assay for Antigen Detection
Organism species: Canis familiaris; Canine (Dog)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Replication Factor C4 (RFC4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Replication Factor C4 (RFC4) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Replication Factor C4 (RFC4) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Replication Factor C4 (RFC4) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Replication Factor C4 (RFC4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Replication Factor C4 (RFC4) CLIA assay for Antigen Detection
Organism species: Sus scrofa; Porcine (Pig)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Replication Factor C4 (RFC4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Replication Factor C4 (RFC4) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Replication Factor C4 (RFC4) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Replication Factor C4 (RFC4) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Replication Factor C4 (RFC4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Replication Factor C4 (RFC4) CLIA assay for Antigen Detection
Organism species: Bos taurus; Bovine (Cattle)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Replication Factor C4 (RFC4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Replication Factor C4 (RFC4) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Replication Factor C4 (RFC4) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Replication Factor C4 (RFC4) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Replication Factor C4 (RFC4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Replication Factor C4 (RFC4) CLIA assay for Antigen Detection
Organism species: Rhesus monkey (Simian)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Replication Factor C4 (RFC4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Replication Factor C4 (RFC4) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Replication Factor C4 (RFC4) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Replication Factor C4 (RFC4) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Replication Factor C4 (RFC4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Replication Factor C4 (RFC4) CLIA assay for Antigen Detection
Organism species: Chicken (Gallus)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Replication Factor C4 (RFC4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Replication Factor C4 (RFC4) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Replication Factor C4 (RFC4) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Replication Factor C4 (RFC4) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Replication Factor C4 (RFC4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Replication Factor C4 (RFC4) CLIA assay for Antigen Detection
Organism species: Ovis aries; Ovine (Sheep)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Replication Factor C4 (RFC4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Replication Factor C4 (RFC4) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Replication Factor C4 (RFC4) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Replication Factor C4 (RFC4) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Replication Factor C4 (RFC4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Replication Factor C4 (RFC4) CLIA assay for Antigen Detection
Organism species: Oryctolagus cuniculus (Rabbit)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Replication Factor C4 (RFC4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Replication Factor C4 (RFC4) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Replication Factor C4 (RFC4) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Replication Factor C4 (RFC4) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Replication Factor C4 (RFC4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Replication Factor C4 (RFC4) CLIA assay for Antigen Detection
Organism species: Cavia (Guinea pig )
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Replication Factor C4 (RFC4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Replication Factor C4 (RFC4) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Replication Factor C4 (RFC4) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Replication Factor C4 (RFC4) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Replication Factor C4 (RFC4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Replication Factor C4 (RFC4) CLIA assay for Antigen Detection
Organism species: Equus caballus; Equine (Horse)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Replication Factor C4 (RFC4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Replication Factor C4 (RFC4) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Replication Factor C4 (RFC4) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Replication Factor C4 (RFC4) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Replication Factor C4 (RFC4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Replication Factor C4 (RFC4) CLIA assay for Antigen Detection
Organism species: Capra hircus; Caprine (Goat)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Replication Factor C4 (RFC4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Replication Factor C4 (RFC4) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Replication Factor C4 (RFC4) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Replication Factor C4 (RFC4) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Replication Factor C4 (RFC4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Replication Factor C4 (RFC4) CLIA assay for Antigen Detection
Organism species: Pan-species (General)
PRODUCT TYPE
CATALOG NO.
PRODUCT NAME
APPLICATIONS
Proteins
NONE
Recombinant Replication Factor C4 (RFC4) Positive Control; Immunogen; SDS-PAGE; WB.
NONE
Native Replication Factor C4 (RFC4) Bioactivity
Antibodies
NONE
Monoclonal Antibody to Replication Factor C4 (RFC4) WB; IHC; ICC; IP.
NONE
Polyclonal Antibody to Replication Factor C4 (RFC4) WB; IHC; ICC; IF.
NONE
Biotin Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) ELISA(Det);IC; IH; IH(P); WB
NONE
APC Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) IHC, WB
NONE
HRP Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) Simple Western; WB
NONE
PE Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) Flow Cytometry
NONE
FITC Linked-Polyclonal Antibody to Replication Factor C4 (RFC4) Flow Cytometry;ICC/IF
Assay Kits
NONE
ELISA Kit for Replication Factor C4 (RFC4) Enzyme-linked immunosorbent assay for Antigen Detection
NONE
CLIA kit for Replication Factor C4 (RFC4) CLIA assay for Antigen Detection
Reference
"Studies of the cloned 37-kDa subunit of activator 1 (replication factor C) of HeLa cells." Proc. Natl. Acad. Sci. U.S.A. 89:5211-5215(1992) [PubMed ] [Europe PMC ] [Abstract ]
"Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed ] [Europe PMC ] [Abstract ]
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." Genome Res. 14:2121-2127(2004) [PubMed ] [Europe PMC ] [Abstract ]
"Purification and characterization of human DNA damage checkpoint Rad complexes." Proc. Natl. Acad. Sci. U.S.A. 98:11236-11241(2001) [PubMed ] [Europe PMC ] [Abstract ]
"Lysine acetylation targets protein complexes and co-regulates major cellular functions." Science 325:834-840(2009) [PubMed ] [Europe PMC ] [Abstract ]
"Initial characterization of the human central proteome." BMC Syst. Biol. 5:17-17(2011) [PubMed ] [Europe PMC ] [Abstract ]
"N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB." Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed ] [Europe PMC ] [Abstract ]
"The consensus coding sequences of human breast and colorectal cancers." Science 314:268-274(2006) [PubMed ] [Europe PMC ] [Abstract ]
