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Tight Junction Protein 2 (TJP2)

X104; ZO-2; ZO2; Zona Occludens 2; Friedreich Ataxia Region Gene X104; Zona occludens protein 2; Zonula occludens protein 2

TJP2 encodes a zonula occluden that is a member of the membrane-associated guanylate kinase homolog family. The encoded protein functions as a component of the tight junction barrier in epithelial and endothelial cells and is necessary for proper assembly of tight junctions. Mutation in this gene have been identified in patients with hypercholanemia. Alternate splicing results in multiple transcript variants. This protein is found in epithelial cell junctions. Isoform A1 is abundant in the heart and brain whereas isoform C1 is expressed at high level in the kidney, pancreas, heart and placenta. In brain and skeletal muscle, only isoform A1 is detectable. Isoform C1 is found in normal as well as in most neoplastic tissues while isoform A1 is present almost exclusively in normal tissue.

Organism species: Homo sapiens (Human)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Tight Junction Protein 2 (TJP2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Tight Junction Protein 2 (TJP2) Bioactivity
Antibodies MR636Hu21 Monoclonal Antibody to Tight Junction Protein 2 (TJP2) WB; IHC; ICC; IP.
PR636Hu01 Polyclonal Antibody to Tight Junction Protein 2 (TJP2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) Flow Cytometry;ICC/IF
Assay Kits KER636Hu ELISA Kit for Tight Junction Protein 2 (TJP2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Tight Junction Protein 2 (TJP2) CLIA assay for Antigen Detection

Organism species: Mus musculus (Mouse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Tight Junction Protein 2 (TJP2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Tight Junction Protein 2 (TJP2) Bioactivity
Antibodies NONE Monoclonal Antibody to Tight Junction Protein 2 (TJP2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Tight Junction Protein 2 (TJP2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Tight Junction Protein 2 (TJP2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Tight Junction Protein 2 (TJP2) CLIA assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Tight Junction Protein 2 (TJP2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Tight Junction Protein 2 (TJP2) Bioactivity
Antibodies NONE Monoclonal Antibody to Tight Junction Protein 2 (TJP2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Tight Junction Protein 2 (TJP2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Tight Junction Protein 2 (TJP2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Tight Junction Protein 2 (TJP2) CLIA assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Tight Junction Protein 2 (TJP2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Tight Junction Protein 2 (TJP2) Bioactivity
Antibodies NONE Monoclonal Antibody to Tight Junction Protein 2 (TJP2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Tight Junction Protein 2 (TJP2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Tight Junction Protein 2 (TJP2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Tight Junction Protein 2 (TJP2) CLIA assay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Tight Junction Protein 2 (TJP2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Tight Junction Protein 2 (TJP2) Bioactivity
Antibodies NONE Monoclonal Antibody to Tight Junction Protein 2 (TJP2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Tight Junction Protein 2 (TJP2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Tight Junction Protein 2 (TJP2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Tight Junction Protein 2 (TJP2) CLIA assay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Tight Junction Protein 2 (TJP2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Tight Junction Protein 2 (TJP2) Bioactivity
Antibodies NONE Monoclonal Antibody to Tight Junction Protein 2 (TJP2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Tight Junction Protein 2 (TJP2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Tight Junction Protein 2 (TJP2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Tight Junction Protein 2 (TJP2) CLIA assay for Antigen Detection

Organism species: Rhesus monkey (Simian)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Tight Junction Protein 2 (TJP2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Tight Junction Protein 2 (TJP2) Bioactivity
Antibodies NONE Monoclonal Antibody to Tight Junction Protein 2 (TJP2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Tight Junction Protein 2 (TJP2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Tight Junction Protein 2 (TJP2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Tight Junction Protein 2 (TJP2) CLIA assay for Antigen Detection

Organism species: Chicken (Gallus)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Tight Junction Protein 2 (TJP2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Tight Junction Protein 2 (TJP2) Bioactivity
Antibodies NONE Monoclonal Antibody to Tight Junction Protein 2 (TJP2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Tight Junction Protein 2 (TJP2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Tight Junction Protein 2 (TJP2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Tight Junction Protein 2 (TJP2) CLIA assay for Antigen Detection

Organism species: Ovis aries; Ovine (Sheep)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Tight Junction Protein 2 (TJP2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Tight Junction Protein 2 (TJP2) Bioactivity
Antibodies NONE Monoclonal Antibody to Tight Junction Protein 2 (TJP2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Tight Junction Protein 2 (TJP2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Tight Junction Protein 2 (TJP2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Tight Junction Protein 2 (TJP2) CLIA assay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Tight Junction Protein 2 (TJP2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Tight Junction Protein 2 (TJP2) Bioactivity
Antibodies NONE Monoclonal Antibody to Tight Junction Protein 2 (TJP2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Tight Junction Protein 2 (TJP2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Tight Junction Protein 2 (TJP2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Tight Junction Protein 2 (TJP2) CLIA assay for Antigen Detection

Organism species: Cavia (Guinea pig )

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Tight Junction Protein 2 (TJP2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Tight Junction Protein 2 (TJP2) Bioactivity
Antibodies NONE Monoclonal Antibody to Tight Junction Protein 2 (TJP2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Tight Junction Protein 2 (TJP2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Tight Junction Protein 2 (TJP2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Tight Junction Protein 2 (TJP2) CLIA assay for Antigen Detection

Organism species: Equus caballus; Equine (Horse)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Tight Junction Protein 2 (TJP2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Tight Junction Protein 2 (TJP2) Bioactivity
Antibodies NONE Monoclonal Antibody to Tight Junction Protein 2 (TJP2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Tight Junction Protein 2 (TJP2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Tight Junction Protein 2 (TJP2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Tight Junction Protein 2 (TJP2) CLIA assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Tight Junction Protein 2 (TJP2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Tight Junction Protein 2 (TJP2) Bioactivity
Antibodies NONE Monoclonal Antibody to Tight Junction Protein 2 (TJP2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Tight Junction Protein 2 (TJP2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Tight Junction Protein 2 (TJP2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Tight Junction Protein 2 (TJP2) CLIA assay for Antigen Detection

Organism species: Pan-species (General)

PRODUCT TYPE CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NONE Recombinant Tight Junction Protein 2 (TJP2) Positive Control; Immunogen; SDS-PAGE; WB.
NONE Native Tight Junction Protein 2 (TJP2) Bioactivity
Antibodies NONE Monoclonal Antibody to Tight Junction Protein 2 (TJP2) WB; IHC; ICC; IP.
NONE Polyclonal Antibody to Tight Junction Protein 2 (TJP2) WB; IHC; ICC; IF.
NONE Biotin Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) ELISA(Det);IC; IH; IH(P); WB
NONE APC Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) IHC, WB
NONE HRP Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) Simple Western; WB
NONE PE Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) Flow Cytometry
NONE FITC Linked-Polyclonal Antibody to Tight Junction Protein 2 (TJP2) Flow Cytometry;ICC/IF
Assay Kits NONE ELISA Kit for Tight Junction Protein 2 (TJP2) Enzyme-linked immunosorbent assay for Antigen Detection
NONE CLIA kit for Tight Junction Protein 2 (TJP2) CLIA assay for Antigen Detection

Reference

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"Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
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"Phosphoproteome of resting human platelets."
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"A quantitative atlas of mitotic phosphorylation."
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"Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography."
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"Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
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"Characterization of the ubinuclein protein as a new member of the nuclear and adhesion complex components (NACos)."
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"Mutations in TJP2 cause progressive cholestatic liver disease."
Nat. Genet. 46:326-328(2014) [PubMed] [Europe PMC] [Abstract]

"Domain-swapped dimerization of the second PDZ domain of ZO2 may provide a structural basis for the polymerization of claudins."
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